ITTO20120837A1 - INNOVATIVE DEVICE BY MEANS OF HEALING SCREW ON DENTAL IMPLANT FOR CONTROLLED RELEASE OF DRUGS AND / OR ANTIBIOTICS, UNIVERSAL, APPLICABLE TO ALL TYPES OF PLANTS. - Google Patents
INNOVATIVE DEVICE BY MEANS OF HEALING SCREW ON DENTAL IMPLANT FOR CONTROLLED RELEASE OF DRUGS AND / OR ANTIBIOTICS, UNIVERSAL, APPLICABLE TO ALL TYPES OF PLANTS. Download PDFInfo
- Publication number
- ITTO20120837A1 ITTO20120837A1 IT000837A ITTO20120837A ITTO20120837A1 IT TO20120837 A1 ITTO20120837 A1 IT TO20120837A1 IT 000837 A IT000837 A IT 000837A IT TO20120837 A ITTO20120837 A IT TO20120837A IT TO20120837 A1 ITTO20120837 A1 IT TO20120837A1
- Authority
- IT
- Italy
- Prior art keywords
- healing
- cap
- screw
- antibiotics
- bone
- Prior art date
Links
- 230000035876 healing Effects 0.000 title claims description 13
- 239000003814 drug Substances 0.000 title claims description 8
- 229940079593 drug Drugs 0.000 title claims description 8
- 239000003242 anti bacterial agent Substances 0.000 title claims description 6
- 229940088710 antibiotic agent Drugs 0.000 title claims description 6
- 239000004053 dental implant Substances 0.000 title claims description 6
- 238000013270 controlled release Methods 0.000 title description 2
- 210000000988 bone and bone Anatomy 0.000 claims description 11
- 230000003115 biocidal effect Effects 0.000 claims description 3
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 2
- 239000000499 gel Substances 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 230000011164 ossification Effects 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims description 2
- 229910052719 titanium Inorganic materials 0.000 claims description 2
- 239000010936 titanium Substances 0.000 claims description 2
- 239000000560 biocompatible material Substances 0.000 claims 1
- 238000009792 diffusion process Methods 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 239000007943 implant Substances 0.000 description 11
- 238000002360 preparation method Methods 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 208000006386 Bone Resorption Diseases 0.000 description 1
- 208000037408 Device failure Diseases 0.000 description 1
- 206010013710 Drug interaction Diseases 0.000 description 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
- 206010018785 Gingival infections Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 210000002805 bone matrix Anatomy 0.000 description 1
- 230000024279 bone resorption Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000002744 extracellular matrix Anatomy 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000009103 reabsorption Effects 0.000 description 1
- 230000002784 sclerotic effect Effects 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/008—Healing caps or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C19/00—Dental auxiliary appliances
- A61C19/06—Implements for therapeutic treatment
- A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
Landscapes
- Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dentistry (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dental Prosthetics (AREA)
Description
DESCRIZIONE DESCRIPTION
Descrizione dell’invenzione industriale dal titolo: Description of the industrial invention entitled:
Dispositivo innovativo mediante vite di guarigione su impianto dentale per il rilascio controllato di farmaci e/o antibiotici, universale, applicabile a tutte le tipologie di impianti Innovative device using a healing screw on a dental implant for the controlled release of drugs and / or antibiotics, universal, applicable to all types of implants
Il dispositivo oggetto del brevetto consente di utilizzare farmaci o antibiotici rispettivamente nella zona gengivale e nella zona in cui l’impianto è a contatto con l’osso. The device covered by the patent allows the use of drugs or antibiotics respectively in the gum area and in the area where the implant is in contact with the bone.
I dosaggi ed i tempi di rilascio in loco delle sostanze contenute nel tappo di guarigione possono essere controllate modulando opportunamente la porosità di tali materiali oppure la grandezza dei fori di rilascio, f II tappo di guarigione può essere applicato a tute le tipologie di impianti già disponibili sui mercato. Le case produttrici di impianti non hanno mai affrontato il caso dell’ interazione farmacologica con il sistemi circostante con cui vanno ad interagire. Più in dettaglio (vedi figura 1), le modifiche in questione riguardano la zona apicale dell’impianto a contato con l’osso, ed il tappo di guarigione. The dosages and on-site release times of the substances contained in the healing cap can be controlled by appropriately modulating the porosity of these materials or the size of the release holes, f The healing cap can be applied to all types of implants already available on the market. The manufacturers of implants have never faced the case of drug interaction with the surrounding systems with which they interact. In more detail (see Figure 1), the changes in question concern the apical area of the implant in contact with the bone, and the healing cap.
Il tappo di guarigione, sulla parte superiore dell’impianto, viene reso cavo in modo da ospitare al suo interno (fig. la) un farmaco atto al rilascio di antibiotici e/o stimolatori di ricrescita tessutali. II contatto del farmaco con l’esterno è assicurato dalla presenza su di esso di fori di grandezza variabile tipicamente 0,2 mm e disposti lungo tutto il perimetro. The healing cap, on the upper part of the implant, is made hollow in order to house (fig. La) a drug suitable for the release of antibiotics and / or tissue regrowth stimulators. The contact of the drug with the outside is ensured by the presence on it of holes of variable size typically 0.2 mm and arranged along the entire perimeter.
I! caricamento del farmaco o antibiotico è anche oggetto del seguente brevetto. La vite può essere riempita mediante siringa con ago smusso, precedentemente fornita al dentista, con il preparato a base antibiotica. In questo caso l’implantologo avrà la possibilità di avere il preparato sempre fresco e disponibile. THE! Loading the drug or antibiotic is also the subject of the following patent. The screw can be filled by means of a syringe with a blunt needle, previously supplied to the dentist, with the antibiotic-based preparation. In this case, the implantologist will have the opportunity to always have the preparation fresh and available.
La preparazione del composto applicabile nel tappo di guarigione può avere diverse tipologie c i realizzazione. The preparation of the compound applicable in the healing cap can have different types and realization.
Si va da composti su base acquosa (gel) a preparati in polvere. They range from water-based compounds (gels) to powder preparations.
’insuccesso di un impianto dentale può essere causato da una non perfetta stabilizzazione all’ato dell'intervento, ma anche da fenomeni di riassorbimento osseo che si manifestano in tempi successivi all’ inserimento. La perdita di tessuto osseo alveolare, che funge da sostegno per gli impianti dentali, piò avvenire sia per motivi fisiologici legati all’età avanzata del paziente, sia per necrosi conseguente ad ùn eccessivo carico da compressione, che può essere determinata da infiammazioni ed infezioni che si originalo sulla superficie della gengiva e che si spingono, nella loro evoluzione successiva, sempre più in profondità verso l’osso. Quest’ultimo caso può verificarsi anche nell’eventualità in cui l’intervento chirurgico sia st^to eseguito correttamente ed in condizione di sterilità perimplantare, poiché le infezioni gengivali possono nascere nel decorso post operatorio. Failure of a dental implant can be caused by an imperfect stabilization at the time of the intervention, but also by bone resorption phenomena that occur after the insertion. The loss of alveolar bone tissue, which acts as a support for dental implants, can occur both for physiological reasons related to the patient's advanced age, and for necrosis resulting from an excessive compression load, which can be caused by inflammation and infections that originates on the surface of the gum and which, in their subsequent evolution, are pushed deeper and deeper into the bone. The latter case can also occur in the event that the surgery has been performed correctly and in a condition of peri-implant sterility, since gum infections can arise in the postoperative course.
In entrambe le eventualità, il risultato finale consiste in un aumento dei processi di riassorbiménto dèlia matrice ossea, che si contrappongono all’attività di neoformazione ossea attorno all’impianto. In questo caso ne consegue una perdita sia di matrice extracellulare, che di componente minerale nonché una diminuzione della densità e della resistenza del tessuto osseo. In both cases, the final result consists in an increase in the processes of reabsorption of the bone matrix, which are opposed to the activity of new bone formation around the implant. In this case it follows a loss of both the extracellular matrix and the mineral component as well as a decrease in the density and strength of the bone tissue.
Un’ulteriore possibilità di fallimento dell’impianto dentale risiede nella grande differenza del modulo elastico tra l’osso (modulo elastico 17.4 GPa) e il titanio di cui è costituita rimpianto (il cui mò i dulo elast ;ico è di circa 105 GPa, contro i 19.8 GPa del dente). Questa rilevante discontinuità elastica tra impianto ed osso sì ripercuote negativamente su quest’ultimo, quando sottoposto a sollecitazioni, producendo micro traumi e micronecrosi che tendono a sclerotizzare l'osso indebolendone la struttura meccanica: la conseguenza ultima è la mobilità dell’impianto. Per fronteggiare efficacemente i problemi esposti, diventa importanti la protezione della zona perimplantare dallo sviluppo di infezioni in maniera continua dopo l’intervento, e favorire la ricrescita ossea e la sua integrazione alla protesi in tempi più rapidi possibili. A further possibility of dental implant failure lies in the great difference in the elastic modulus between the bone (elastic modulus 17.4 GPa) and the titanium of which it is made up of regret (whose elastic modulus is about 105 GPa, against 19.8 GPa of the tooth). This significant elastic discontinuity between implant and bone has a negative impact on the latter, when subjected to stress, producing micro trauma and micronecrosis that tend to sclerotic the bone weakening its mechanical structure: the ultimate consequence is the mobility of the implant. To effectively deal with the problems exposed, it is important to protect the peri-implant area from the development of infections continuously after surgery, and to promote bone regrowth and its integration into the prosthesis as quickly as possible.
Claims (5)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000837A ITTO20120837A1 (en) | 2012-09-27 | 2012-09-27 | INNOVATIVE DEVICE BY MEANS OF HEALING SCREW ON DENTAL IMPLANT FOR CONTROLLED RELEASE OF DRUGS AND / OR ANTIBIOTICS, UNIVERSAL, APPLICABLE TO ALL TYPES OF PLANTS. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000837A ITTO20120837A1 (en) | 2012-09-27 | 2012-09-27 | INNOVATIVE DEVICE BY MEANS OF HEALING SCREW ON DENTAL IMPLANT FOR CONTROLLED RELEASE OF DRUGS AND / OR ANTIBIOTICS, UNIVERSAL, APPLICABLE TO ALL TYPES OF PLANTS. |
Publications (1)
Publication Number | Publication Date |
---|---|
ITTO20120837A1 true ITTO20120837A1 (en) | 2012-12-27 |
Family
ID=47633385
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT000837A ITTO20120837A1 (en) | 2012-09-27 | 2012-09-27 | INNOVATIVE DEVICE BY MEANS OF HEALING SCREW ON DENTAL IMPLANT FOR CONTROLLED RELEASE OF DRUGS AND / OR ANTIBIOTICS, UNIVERSAL, APPLICABLE TO ALL TYPES OF PLANTS. |
Country Status (1)
Country | Link |
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IT (1) | ITTO20120837A1 (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0864299A1 (en) * | 1997-03-10 | 1998-09-16 | Stiftung für klinische Forschung (SKF) zur Förderung der oralen Gesundheit | Device for use with dental implants for applying medicament |
WO2001045585A1 (en) * | 1999-12-21 | 2001-06-28 | Consiglio Nazionale Delle Ricerche | Dental prosthesis with means for the release of active substances |
-
2012
- 2012-09-27 IT IT000837A patent/ITTO20120837A1/en unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0864299A1 (en) * | 1997-03-10 | 1998-09-16 | Stiftung für klinische Forschung (SKF) zur Förderung der oralen Gesundheit | Device for use with dental implants for applying medicament |
WO2001045585A1 (en) * | 1999-12-21 | 2001-06-28 | Consiglio Nazionale Delle Ricerche | Dental prosthesis with means for the release of active substances |
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