ITRM20050085A1 - METHOD FOR THE SIMULTANEOUS DETERMINATION OF PURINE AND PYRIMIDINE DERIVATIVES, N-ACETYLATED AMINO ACIDS AND DICARBOSSYLIC ACIDS IN A BIOLOGICAL SAMPLE BY LIQUID CHROMATOGRAPHY AT HIGH PERFORMANCE (HPLC) AND ITS KIT. - Google Patents

METHOD FOR THE SIMULTANEOUS DETERMINATION OF PURINE AND PYRIMIDINE DERIVATIVES, N-ACETYLATED AMINO ACIDS AND DICARBOSSYLIC ACIDS IN A BIOLOGICAL SAMPLE BY LIQUID CHROMATOGRAPHY AT HIGH PERFORMANCE (HPLC) AND ITS KIT.

Info

Publication number
ITRM20050085A1
ITRM20050085A1 ITRM20050085A ITRM20050085A1 IT RM20050085 A1 ITRM20050085 A1 IT RM20050085A1 IT RM20050085 A ITRM20050085 A IT RM20050085A IT RM20050085 A1 ITRM20050085 A1 IT RM20050085A1
Authority
IT
Italy
Prior art keywords
acids
dicarbossylic
purine
hplc
kit
Prior art date
Application number
Other languages
Italian (it)
Inventor
Angela Maria Amorini
Bruno Giardina
Giuseppe Lazzarino
Paola Leone
Barbara Tavazzi
Original Assignee
Angela Maria Amorini
Bruno Giardina
Giuseppe Lazzarino
Paola Leone
Barbara Tavazzi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angela Maria Amorini, Bruno Giardina, Giuseppe Lazzarino, Paola Leone, Barbara Tavazzi filed Critical Angela Maria Amorini
Priority to ITRM20050085 priority Critical patent/ITRM20050085A1/en
Priority to PCT/IT2006/000116 priority patent/WO2006090428A2/en
Publication of ITRM20050085A1 publication Critical patent/ITRM20050085A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/366—Ion-pair, e.g. ion-pair reversed phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/62—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving urea
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • B01D15/426—Specific type of solvent

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ITRM20050085 2005-02-28 2005-02-28 METHOD FOR THE SIMULTANEOUS DETERMINATION OF PURINE AND PYRIMIDINE DERIVATIVES, N-ACETYLATED AMINO ACIDS AND DICARBOSSYLIC ACIDS IN A BIOLOGICAL SAMPLE BY LIQUID CHROMATOGRAPHY AT HIGH PERFORMANCE (HPLC) AND ITS KIT. ITRM20050085A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ITRM20050085 ITRM20050085A1 (en) 2005-02-28 2005-02-28 METHOD FOR THE SIMULTANEOUS DETERMINATION OF PURINE AND PYRIMIDINE DERIVATIVES, N-ACETYLATED AMINO ACIDS AND DICARBOSSYLIC ACIDS IN A BIOLOGICAL SAMPLE BY LIQUID CHROMATOGRAPHY AT HIGH PERFORMANCE (HPLC) AND ITS KIT.
PCT/IT2006/000116 WO2006090428A2 (en) 2005-02-28 2006-02-28 Method for the separation and simultaneous direct determination of compounds belonging to at least one of the groups chosen among purines and pyrimidines, n- acetylated amino acids, mono and dicarboxylic acids, sulphurylated compounds, nitrosylated compounds, bifunctional aldehydes, vitamins of group b, and derivatives ther

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM20050085 ITRM20050085A1 (en) 2005-02-28 2005-02-28 METHOD FOR THE SIMULTANEOUS DETERMINATION OF PURINE AND PYRIMIDINE DERIVATIVES, N-ACETYLATED AMINO ACIDS AND DICARBOSSYLIC ACIDS IN A BIOLOGICAL SAMPLE BY LIQUID CHROMATOGRAPHY AT HIGH PERFORMANCE (HPLC) AND ITS KIT.

Publications (1)

Publication Number Publication Date
ITRM20050085A1 true ITRM20050085A1 (en) 2006-09-01

Family

ID=36691766

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM20050085 ITRM20050085A1 (en) 2005-02-28 2005-02-28 METHOD FOR THE SIMULTANEOUS DETERMINATION OF PURINE AND PYRIMIDINE DERIVATIVES, N-ACETYLATED AMINO ACIDS AND DICARBOSSYLIC ACIDS IN A BIOLOGICAL SAMPLE BY LIQUID CHROMATOGRAPHY AT HIGH PERFORMANCE (HPLC) AND ITS KIT.

Country Status (2)

Country Link
IT (1) ITRM20050085A1 (en)
WO (1) WO2006090428A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
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EP1962097A1 (en) * 2007-02-23 2008-08-27 SeQuant AB Mass spectrometric quantitative detection of methyl malonic acid and succinic acid using hilic on a zwitterionic stationary phase
ITRM20070200A1 (en) * 2007-04-06 2008-10-07 Angela Maria Amorini AUTOMATED SYSTEM FOR COLLECTING, DETECTION AND ANALYSIS OF BIOLOGICAL LIQUIDS FOR THE BIOCHEMICAL-CLINICAL MONITORING OF A PATIENT PREFERABLY IN INTENSIVE THERAPY.
HRP20080563A2 (en) * 2008-11-05 2010-08-31 Institut Ruđer Bošković Proteomics profiles and detection methods of proteins in blood plasma
CN102226795A (en) * 2011-03-31 2011-10-26 宁波双伟制药有限公司 Method for determining content of vitamin B12 in complex vitamin B and diclofenac sodium tablet through high performance liquid chromatography
RU2495425C1 (en) * 2012-06-13 2013-10-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет Министерства здравоохранения и социального развития Российской Федерации" Method of extracting azathioprine from biological fluids
CN103091442A (en) * 2012-11-13 2013-05-08 江苏艾兰得营养品有限公司 Chromatographic method for determination of vitamin B12 content
CN103823009B (en) * 2014-03-14 2015-02-18 国家烟草质量监督检验中心 Application of liquid chromatography tandem mass spectrogram method in biological monitoring of 3-alkylation adenine in mass smokers
CN103808836B (en) * 2014-03-14 2015-01-07 国家烟草质量监督检验中心 Determination method of 3-alkylated adenine DNA adducts in urine
CN103869037B (en) * 2014-03-14 2015-06-24 国家烟草质量监督检验中心 Application of liquid chromatography-tandem mass spectrometry to biological monitoring of 3-methyladenine in large-scale smoker samples
CN103822991B (en) * 2014-03-14 2015-02-11 国家烟草质量监督检验中心 Application of liquid chromatography tandem mass spectrometry method in biological monitoring on 3-ethyl adenines among samples of large-scale smokers
CA2990681A1 (en) * 2015-07-13 2017-01-19 General Electric Company Amines analysis by ion chromatography
CN105136930A (en) * 2015-09-02 2015-12-09 湖南科伦制药有限公司 Detection method for thymosin for injection
RU2617176C1 (en) * 2016-03-10 2017-04-21 Государственное бюджетное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет" Министерства здравоохранения Российской Федерации Method for determination of 2,6-bis-[bis-(beta-oxyethyl)-amino]-4,8-di-n-piperidino-pyrimido(5,4-d)pyrimidine in biological material
US11099162B2 (en) 2016-09-30 2021-08-24 Shimadzu Corporation Method for analyzing active ingredients of cannabis and control program for liquid chromatograph
CN106940350A (en) * 2017-02-28 2017-07-11 淮安市第人民医院 A kind of method for determining multiple water-soluble vitamin in dimension belladonna solution again
CN107515265A (en) * 2017-08-31 2017-12-26 未名生物医药有限公司 A kind of assay method of urate oxidase activity
CN107860847A (en) * 2017-11-14 2018-03-30 济南维瑞医药科技开发有限公司 Vitamin B in one kind detection multivitamin preparation12Method about material
CN108333289B (en) * 2018-02-07 2020-03-20 吉林师范大学 Method for controlling grub content through multi-component detection
CN109142564A (en) * 2018-07-26 2019-01-04 内蒙古蒙牛乳业（集团）股份有限公司 Method that is a kind of while detecting vitamin A. D. E
CN109580858A (en) * 2019-01-31 2019-04-05 中山大学 The extraction of 5 kinds of gradient elutions and its content assaying method in a kind of wide dragon
CN111157667B (en) * 2019-12-25 2022-09-20 新绎健康科技有限公司 Method for simultaneously detecting malonaldehyde, uric acid, nucleotide and derivatives thereof
CN111426762B (en) * 2020-03-31 2022-04-12 湖北航天化学技术研究所 Method for measuring content of aminoguanidine nitrate and diaminoguanidine nitrate
CN112858518A (en) * 2021-01-29 2021-05-28 上海体育学院 Method for extracting acadesine from urine and detection method
CN113916809A (en) * 2021-09-06 2022-01-11 首都儿科研究所附属儿童医院 POCT (Point of Care testing) detection method for hypoxanthine content in urine and application
CN114487243B (en) * 2021-12-29 2023-04-18 北京康仁堂药业有限公司 Characteristic map of ground beetle water extract and preparation thereof and construction method of characteristic map

Also Published As

Publication number Publication date
WO2006090428A2 (en) 2006-08-31
WO2006090428A3 (en) 2006-09-28

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