ITPD940011A1 - Rivestimento di oggetti biomedicali mediante microsfere ottenute da polimeri biocompatibili - Google Patents
Rivestimento di oggetti biomedicali mediante microsfere ottenute da polimeri biocompatibiliInfo
- Publication number
- ITPD940011A1 ITPD940011A1 IT94PD000011A ITPD940011A ITPD940011A1 IT PD940011 A1 ITPD940011 A1 IT PD940011A1 IT 94PD000011 A IT94PD000011 A IT 94PD000011A IT PD940011 A ITPD940011 A IT PD940011A IT PD940011 A1 ITPD940011 A1 IT PD940011A1
- Authority
- IT
- Italy
- Prior art keywords
- coating
- biocompatible polymers
- microspheres obtained
- microspheres
- biomedical objects
- Prior art date
Links
- 239000011248 coating agent Substances 0.000 title abstract 3
- 238000000576 coating method Methods 0.000 title abstract 3
- 239000004005 microsphere Substances 0.000 title abstract 3
- 229920000249 biocompatible polymer Polymers 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
- C08J5/12—Bonding of a preformed macromolecular material to the same or other solid material such as metal, glass, leather, e.g. using adhesives
- C08J5/124—Bonding of a preformed macromolecular material to the same or other solid material such as metal, glass, leather, e.g. using adhesives using adhesives based on a macromolecular component
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
- C08J5/12—Bonding of a preformed macromolecular material to the same or other solid material such as metal, glass, leather, e.g. using adhesives
- C08J5/122—Bonding of a preformed macromolecular material to the same or other solid material such as metal, glass, leather, e.g. using adhesives using low molecular chemically inert solvents, swelling or softening agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Manufacturing & Machinery (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Materials Engineering (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Paints Or Removers (AREA)
Abstract
La presente invenzione si riferisce ad un nuovo processo per la preparazione di un coating (rivestimento) della superficie esterna di oggetti biomedicali aventi caratteristiche chimico/fisiche complesse, come una elevata elasticità, mediante l'impiego di microsfere da polimeri biocompatibili e/o bioassorbibili, quali ad esempio gli esteri dell'acido ialuronico. Le microsfere possono anche incorporare principi attivi quali antibiotici, antibatterici, antimicotici, antimicrobici e agenti proteici.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT94PD000011A ITPD940011A1 (it) | 1994-01-28 | 1994-01-28 | Rivestimento di oggetti biomedicali mediante microsfere ottenute da polimeri biocompatibili |
AU16628/95A AU1662895A (en) | 1994-01-28 | 1995-01-27 | Coating of biomedical objects with microspheres obtained with biocompatible polymers |
PCT/EP1995/000316 WO1995020381A1 (en) | 1994-01-28 | 1995-01-27 | Coating of biomedical objects with microspheres obtained with biocompatible polymers |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT94PD000011A ITPD940011A1 (it) | 1994-01-28 | 1994-01-28 | Rivestimento di oggetti biomedicali mediante microsfere ottenute da polimeri biocompatibili |
Publications (2)
Publication Number | Publication Date |
---|---|
ITPD940011A0 ITPD940011A0 (it) | 1994-01-28 |
ITPD940011A1 true ITPD940011A1 (it) | 1995-07-28 |
Family
ID=11390531
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT94PD000011A ITPD940011A1 (it) | 1994-01-28 | 1994-01-28 | Rivestimento di oggetti biomedicali mediante microsfere ottenute da polimeri biocompatibili |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU1662895A (it) |
IT (1) | ITPD940011A1 (it) |
WO (1) | WO1995020381A1 (it) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6335383B1 (en) * | 1994-10-18 | 2002-01-01 | Ethicon, Inc. | Microdispersions for coating surgical devices |
US5837752A (en) * | 1997-07-17 | 1998-11-17 | Massachusetts Institute Of Technology | Semi-interpenetrating polymer networks |
DE10025803A1 (de) * | 2000-05-24 | 2001-12-20 | Jms Co Ltd | Polymeroberfläche mit biologisch aktiven Eigenschaften und Verfahren zu ihrer Herstellung |
CA2457564C (en) | 2001-10-05 | 2009-04-07 | Surmodics, Inc. | Particle immobilized coatings and uses thereof |
CN102068324B (zh) * | 2011-01-21 | 2013-06-19 | 南京师范大学 | 一种具有抗凝血效果的心脏或血管补片的制备方法 |
CN102068323B (zh) * | 2011-01-21 | 2014-03-26 | 南京师范大学 | 一种具有抗凝血效果的心脏或血管补片 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69111245T2 (de) * | 1990-08-14 | 1995-11-23 | Howmedica | Knochenwachstumsstimulator. |
IT1259100B (it) * | 1992-05-20 | 1996-03-11 | Lanfranco Callegaro | Uso di idrogeli per il bloccaggio di sistemi protesici |
US5395666A (en) * | 1993-01-08 | 1995-03-07 | Lrc Products Ltd. | Flexible elastomeric article with enhanced lubricity |
GB9300746D0 (en) * | 1993-01-15 | 1993-03-03 | Univ Southampton | Prosthesis |
-
1994
- 1994-01-28 IT IT94PD000011A patent/ITPD940011A1/it not_active IP Right Cessation
-
1995
- 1995-01-27 AU AU16628/95A patent/AU1662895A/en not_active Abandoned
- 1995-01-27 WO PCT/EP1995/000316 patent/WO1995020381A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
AU1662895A (en) | 1995-08-15 |
WO1995020381A1 (en) | 1995-08-03 |
ITPD940011A0 (it) | 1994-01-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2273907A1 (en) | Composition of a surface-treatment agent used for metallic material and the treating method | |
IT1271406B (it) | Procedimento per la preparazione di polimeri dell'etilene e prodotti ottenuti | |
EP1181903A3 (en) | A stent for angioplasty and associated production process | |
AU3147095A (en) | Incorporation of biologically active molecules into bioactive glasses | |
CA2230492A1 (en) | Human growth hormone variants | |
CA2211118A1 (en) | Stable lipid-comprising drug delivery complexes and methods for their production | |
CA2468916A1 (en) | A stable oxaliplatin solution formulation | |
MY107267A (en) | Wound gel compositions and methods of using them. | |
HUP9800467A3 (en) | Use of hyaluronic acid for producing pharmaceutical compns. for the treatment of interstitial cystitis | |
HU913776D0 (en) | Process for the production of heparosane-n,o-sulphates, and medical preparations containing them as active agents | |
MX9603465A (es) | N-pirazolilanilinas y n-pirazolilaminopiridinas como agentes pesticidas. | |
ITPD940011A1 (it) | Rivestimento di oggetti biomedicali mediante microsfere ottenute da polimeri biocompatibili | |
ITRM910144A1 (it) | Fibra di ceramica, metallo o carbonio rivestita e procedimento diproduzione | |
AU1384995A (en) | Human circulating cytokine cc-1 | |
GB2336537A (en) | Stannous fluoride gel with improved stand-up | |
CA2011008A1 (en) | Egf variants and pharmaceutical use thereof | |
BG102342A (en) | Optical active derivative of phenylpyrimidine as an anlgesics | |
AU634003B2 (en) | 4-benzyl-5-phenyl-2,4-dihydro-3h-1,2,4-triazol-3-ones and their use as anticonvulsants | |
IT1247884B (it) | Esteri arilalchilici dell'acido 4,5 diidrossi-9,10-diidro-9,10-diosso 2-antracencarbossilico ad azione terapeutica | |
ES2166800T3 (es) | Procedimiento para la preparacion de o,s-acetales de 2,2-difluoroceteno sililo y o,s-esteres del acido alfa,alfa-difluoro-beta-sililoxi-1,3-dioxolan-4-propanoico. | |
IE870577L (en) | Topical amide preparation | |
ITCA950005A0 (it) | Pirazolo - derivati ad attivita' antitumorale, processo per la loro preparazione e composizioni farmaceutiche che li contengono , e inter-medi di tale processo. | |
TW372873B (en) | A novel anti-neoplastic cytokine | |
ITMI911877A0 (it) | Enzimi fibrinolitici ammidati e loro precursori, e processi per la loro preparazione | |
ITMI922018A0 (it) | Bassi polimeri dell'n-vinilpirrolidone monofunzionalizzati ad un estremo per la preparazione di coniugati con enzimi, polipeptidi farmaci |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
0003 | Withdrawn |