ITPA20110004A1 - INTRACAMERULAR INJECTION FOR ANESTHESIA AND PUPILAR DILATION (MIDRIASI). - Google Patents
INTRACAMERULAR INJECTION FOR ANESTHESIA AND PUPILAR DILATION (MIDRIASI). Download PDFInfo
- Publication number
- ITPA20110004A1 ITPA20110004A1 IT000004A ITPA20110004A ITPA20110004A1 IT PA20110004 A1 ITPA20110004 A1 IT PA20110004A1 IT 000004 A IT000004 A IT 000004A IT PA20110004 A ITPA20110004 A IT PA20110004A IT PA20110004 A1 ITPA20110004 A1 IT PA20110004A1
- Authority
- IT
- Italy
- Prior art keywords
- injection
- anesthesia
- intracamerular
- dilation
- midriasi
- Prior art date
Links
- 206010002091 Anaesthesia Diseases 0.000 title claims description 4
- 230000037005 anaesthesia Effects 0.000 title claims description 4
- 230000010339 dilation Effects 0.000 title claims description 4
- 239000007924 injection Substances 0.000 title claims description 3
- 238000002347 injection Methods 0.000 title claims description 3
- 230000001179 pupillary effect Effects 0.000 claims description 5
- 208000006550 Mydriasis Diseases 0.000 claims description 4
- 230000036592 analgesia Effects 0.000 claims description 3
- 230000000202 analgesic effect Effects 0.000 claims description 2
- 230000003110 anti-inflammatory effect Effects 0.000 claims description 2
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims description 2
- 239000004327 boric acid Substances 0.000 claims description 2
- 229960000710 cyclopentolate hydrochloride Drugs 0.000 claims description 2
- RHKZVMUBMXGOLL-UHFFFAOYSA-N cyclopentolate hydrochloride Chemical compound Cl.C1CCCC1(O)C(C(=O)OCCN(C)C)C1=CC=CC=C1 RHKZVMUBMXGOLL-UHFFFAOYSA-N 0.000 claims description 2
- 229940079593 drug Drugs 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims description 2
- 229960004393 lidocaine hydrochloride Drugs 0.000 claims description 2
- YECIFGHRMFEPJK-UHFFFAOYSA-N lidocaine hydrochloride monohydrate Chemical compound O.[Cl-].CC[NH+](CC)CC(=O)NC1=C(C)C=CC=C1C YECIFGHRMFEPJK-UHFFFAOYSA-N 0.000 claims description 2
- 229960003733 phenylephrine hydrochloride Drugs 0.000 claims description 2
- OCYSGIYOVXAGKQ-FVGYRXGTSA-N phenylephrine hydrochloride Chemical compound [H+].[Cl-].CNC[C@H](O)C1=CC=CC(O)=C1 OCYSGIYOVXAGKQ-FVGYRXGTSA-N 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- 239000008227 sterile water for injection Substances 0.000 claims description 2
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 230000000694 effects Effects 0.000 claims 1
- 230000000144 pharmacologic effect Effects 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 208000002177 Cataract Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 210000002159 anterior chamber Anatomy 0.000 description 1
- 239000003889 eye drop Substances 0.000 description 1
- 229940012356 eye drops Drugs 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Description
Descrizione dell’invenzione industriale dal titolo: INIEZIONE INTRACAMERULA RE PER ANESTESIA E DILATAZIONE PUPILLARE Description of the industrial invention entitled: INTRACAMERULA RE INJECTION FOR ANESTHESIA AND PUPILLARY EXPANSION
(MIDRIASI) (MIDRIASIS)
DESCRIZIONE DESCRIPTION
Fa presente invenzione ha per oggetto una preparazione galenica sterile di farmaco iniettabile di 10 mi, per uso chirurgico intraoculare, composta da: The present invention relates to a sterile galenic preparation of injectable drug of 10 ml, for intraocular surgical use, consisting of:
Ciclopentolato idrocloruro mg 2, Fenilefrina ldrocloruto mg 30, Lidocaina Idrocloruro mg 20, Edta sodico mg 2, Acido borico polvere mg 7,7 e Acqua sterile iniettabile mi 2, finalizzata al conseguimento della dilatazione pupillare (midriasi fannacologica), analgesia e effetto antalgico e antiflogistico. Cyclopentolate hydrochloride mg 2, Phenylephrine hydrochloride mg 30, Lidocaine hydrochloride mg 20, Edta sodium mg 2, Boric acid powder mg 7.7 and Sterile water for injection 2 ml, aimed at achieving pupillary dilation (mydriasis fannacologica), analgesia and analgesic effect and anti-inflammatory.
Nell’ambito della chirurgia oculare, tradizionalmente, la dilatazione pupillare e l’analgesia vengono ottenute tramite instillazione pre-operatoria di colliri topici ad uso esterno, necessitando dei tempi di attesa di efficacia dei principi attivi degli stessi. L’invenzione, che verrà ora spiegata, semplifica e riduce i tempi pre-operatori in ambito di chirurgia oculare di cataratta o di altro intervento in camera anteriore o posteriore che necessiti di midriasi. In the field of eye surgery, traditionally, pupillary dilation and analgesia are obtained through pre-operative instillation of topical eye drops for external use, requiring waiting times for the effectiveness of the active ingredients of the same. The invention, which will now be explained, simplifies and reduces pre-operative times in the field of eye cataract surgery or other anterior or posterior chamber surgery that requires mydriasis.
Dopo avere eseguito il tunnel corneale, con una sola manovra operatoria, è sufficiente iniettare in camera anteriore 1 mi della preparazione in questione, per ottenere immediata e prolungata midriasi, garantire l’anestesia occorrente per tutta la durata dell’intervento e ridurre la flogosi (infiammazione post chirurgica). After having performed the corneal tunnel, with a single operative maneuver, it is sufficient to inject 1 ml of the preparation in question into the anterior chamber, to obtain immediate and prolonged mydriasis, guarantee the necessary anesthesia for the entire duration of the operation and reduce inflammation ( post surgical inflammation).
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000004A ITPA20110004A1 (en) | 2011-02-23 | 2011-02-23 | INTRACAMERULAR INJECTION FOR ANESTHESIA AND PUPILAR DILATION (MIDRIASI). |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000004A ITPA20110004A1 (en) | 2011-02-23 | 2011-02-23 | INTRACAMERULAR INJECTION FOR ANESTHESIA AND PUPILAR DILATION (MIDRIASI). |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITPA20110004A1 true ITPA20110004A1 (en) | 2012-08-24 |
Family
ID=43976255
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT000004A ITPA20110004A1 (en) | 2011-02-23 | 2011-02-23 | INTRACAMERULAR INJECTION FOR ANESTHESIA AND PUPILAR DILATION (MIDRIASI). |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | ITPA20110004A1 (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6218428B1 (en) * | 2000-04-28 | 2001-04-17 | Emil Chynn | Ophthalmic composition |
| WO2004010894A2 (en) * | 2002-07-30 | 2004-02-05 | Omeros Corporation | Ophthalmologic irrigation solutions and method |
| WO2006095095A1 (en) * | 2005-03-09 | 2006-09-14 | Laboratoires Thea | Ophthalmologic compositions and use mode thereof |
| US20090215735A1 (en) * | 2002-02-25 | 2009-08-27 | Alcon, Inc. | Topical solution formulations containing a corticosteroid and a cyclodextrin |
-
2011
- 2011-02-23 IT IT000004A patent/ITPA20110004A1/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6218428B1 (en) * | 2000-04-28 | 2001-04-17 | Emil Chynn | Ophthalmic composition |
| US20090215735A1 (en) * | 2002-02-25 | 2009-08-27 | Alcon, Inc. | Topical solution formulations containing a corticosteroid and a cyclodextrin |
| WO2004010894A2 (en) * | 2002-07-30 | 2004-02-05 | Omeros Corporation | Ophthalmologic irrigation solutions and method |
| WO2006095095A1 (en) * | 2005-03-09 | 2006-09-14 | Laboratoires Thea | Ophthalmologic compositions and use mode thereof |
Non-Patent Citations (1)
| Title |
|---|
| BEHNDIG A ET AL: "Evaluation of surgical performance with intracameral mydriatics in phacoemulsification surgery", ACTA OPHTHALMOLOGICA SCANDINAVICA, HVIDOVRE, DK, vol. 82, no. 2, 1 January 2004 (2004-01-01), pages 144 - 147, XP002350415, ISSN: 1395-3907, DOI: 10.1111/J.1600-0420.2004.00241.X * |
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