ITMI912225A0 - QUATERNARY AMMONIUM DERIVATIVES OF (-) AND (+)-3-(10 H-PHENOTHIAZIN-10-ILMETHYL)-L-AZABICICLE (2.2.2.)OCTANE - Google Patents

QUATERNARY AMMONIUM DERIVATIVES OF (-) AND (+)-3-(10 H-PHENOTHIAZIN-10-ILMETHYL)-L-AZABICICLE (2.2.2.)OCTANE

Info

Publication number
ITMI912225A0
ITMI912225A0 IT91MI2225A ITMI912225A ITMI912225A0 IT MI912225 A0 ITMI912225 A0 IT MI912225A0 IT 91MI2225 A IT91MI2225 A IT 91MI2225A IT MI912225 A ITMI912225 A IT MI912225A IT MI912225 A0 ITMI912225 A0 IT MI912225A0
Authority
IT
Italy
Prior art keywords
azabicicle
ilmethyl
phenothiazin
octane
quaternary ammonium
Prior art date
Application number
IT91MI2225A
Other languages
Italian (it)
Inventor
Raffaele Giorgi
Alessandro Subissi
Luigi Turbanti
Original Assignee
Lab Guidotti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lab Guidotti filed Critical Lab Guidotti
Publication of ITMI912225A0 publication Critical patent/ITMI912225A0/en
Priority to ITMI912225A priority Critical patent/IT1251161B/en
Priority to HU9400273A priority patent/HUT66570A/en
Priority to BR9206339A priority patent/BR9206339A/en
Priority to MA22900A priority patent/MA22611A1/en
Priority to JP5503276A priority patent/JPH06509570A/en
Priority to PCT/EP1992/001759 priority patent/WO1993003029A1/en
Priority to EP92916942A priority patent/EP0599896A1/en
Priority to CS94248A priority patent/CZ24894A3/en
Priority to CA002114844A priority patent/CA2114844A1/en
Priority to AU24173/92A priority patent/AU2417392A/en
Priority to SK115-94A priority patent/SK11594A3/en
Priority to EC1992000859A priority patent/ECSP920859A/en
Priority to ZA925852A priority patent/ZA925852B/en
Priority to TNTNSN92073A priority patent/TNSN92073A1/en
Priority to MX9204539A priority patent/MX9204539A/en
Priority to CN92109021A priority patent/CN1071667A/en
Priority to PT100765A priority patent/PT100765A/en
Publication of ITMI912225A1 publication Critical patent/ITMI912225A1/en
Priority to NO940366A priority patent/NO940366D0/en
Priority to FI940530A priority patent/FI940530A/en
Priority to BG98439A priority patent/BG98439A/en
Application granted granted Critical
Publication of IT1251161B publication Critical patent/IT1251161B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ITMI912225A 1991-08-07 1991-08-07 QUATERNARY AMMONIUM DERIVATIVES OF (-) AND (+) - 3- (10 H-PHENOTHIAZIN-10-ILMETHYL) -L-AZABICYCLE (2.2.2.) OCT AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IT1251161B (en)

Priority Applications (20)

Application Number Priority Date Filing Date Title
ITMI912225A IT1251161B (en) 1991-08-07 1991-08-07 QUATERNARY AMMONIUM DERIVATIVES OF (-) AND (+) - 3- (10 H-PHENOTHIAZIN-10-ILMETHYL) -L-AZABICYCLE (2.2.2.) OCT AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
SK115-94A SK11594A3 (en) 1991-08-07 1992-08-03 (+) and (-) 10-(1-azabicyclo (2.2.2.) oct-3-yl methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for their preparation
BR9206339A BR9206339A (en) 1991-08-07 1992-08-03 (-) and (+) 10- (1-azabicycles (2.2.2) OCT-3-IL-Methyl) -10 H- Ammonia derivatives of quaternary phenothiazine, pharmaceutical compositions containing them and process for obtaining them
MA22900A MA22611A1 (en) 1991-08-07 1992-08-03 QUATERNARY AMMONIUM DERIVATIVES OF (+) AND (-) 10- (1-AZABICYCLO (2,2,2) OCT-3-YL-METHYL) -10-H-PHENO-THIAZINE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND METHOD FOR THEIR PREPARATION.
JP5503276A JPH06509570A (en) 1991-08-07 1992-08-03 Pharmaceutical compositions having (-) and (+) 10-(1-azabicyclo[2.2.2.]oct-3-yl-methyl)-10H-phenothiazine quaternary ammonium derivatives and their formulation process
PCT/EP1992/001759 WO1993003029A1 (en) 1991-08-07 1992-08-03 (-) and (+) 10-(1-azabicyclo[2.2.2.]oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for their preparation
EP92916942A EP0599896A1 (en) 1991-08-07 1992-08-03 (-) and (+) 10-(1-azabicyclo 2.2.2.]oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for their preparation
CS94248A CZ24894A3 (en) 1991-08-07 1992-08-03 Quaternary ammonium derivatives (-) and (+)-10- (azabicyclo/2.2.2/-oct-3-yl-methyl)-10h-phenothiazine, process of their preparation and pharmaceutical preparations in which they are comprised
CA002114844A CA2114844A1 (en) 1991-08-07 1992-08-03 (-) and (+) 10-(1-azabicyclo[2.2.2.]oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for their preparation
AU24173/92A AU2417392A (en) 1991-08-07 1992-08-03 (-) and (+) 10-(1-azabicyclo{2.2.2.}oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for their preparation
HU9400273A HUT66570A (en) 1991-08-07 1992-08-03 (-) and (+) 10-(1-azabicyclo[2,2,2]oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for producing them
ZA925852A ZA925852B (en) 1991-08-07 1992-08-04 (-) and (+) 10-(1-azabicyclo(2.2.2.)oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for their preparation.
EC1992000859A ECSP920859A (en) 1991-08-07 1992-08-04 QUATERNARY AMMONIUM DERIVATIVES (-) AND (+) 10- (1 - AZABICICLO [2.2.2] OCT - 3 - IL - METHYL) - 10 H- PHENOTIAZINE, PROCEDURE TO OBTAIN THEM AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
TNTNSN92073A TNSN92073A1 (en) 1991-08-07 1992-08-05 QUATERNARY AMMONIUM DERIVATIVES OF (+) AND (-) 10- (1-AZABICYCLO [2,2,2] OCT-3-YL-METHYL) -10-H-PHENOTHIAZINE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION
MX9204539A MX9204539A (en) 1991-08-07 1992-08-05 QUATERNARY AMMONIUM DERIVATIVES (-) AND (+) 10- (1-AZABICICLO (2.2.2) OCT-3-IL-METHYL) -10 H-PHENOTIAZINE, PROCEDURE TO OBTAIN THEM AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
CN92109021A CN1071667A (en) 1991-08-07 1992-08-06 Phenothiazine quaternary ammonium derivative and process for preparing composition thereof
PT100765A PT100765A (en) 1991-08-07 1992-08-07 (+) 10- (1-AZABICYCLO (2.2.2.) OCT-3-IL-METHYL) -10H-PHENOTIAZINE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION
NO940366A NO940366D0 (en) 1991-08-07 1994-02-04 Quaternary (-) and (Q) 10- (1-azabicyclo (2.2.2. Oct-3-yl-methyl) -10-H-phenothiazine ammonium derivatives, pharmaceutical preparations containing them, and methods for their preparation
FI940530A FI940530A (en) 1991-08-07 1994-02-04 (-) and (+) 10- (1-Azabicyclo (2.2.2.) oct-3-yl-methyl) -10H-phenothiazine quaternary ammonium derivatives, pharmaceutical compounds containing them and process for preparing them
BG98439A BG98439A (en) 1991-08-07 1994-02-07 Quaternary ammonium derivatives of (-) and (+) 10-(1-azobicyclo /2.2.2/oct-3-il-methyl)-1oh-phenothiazine, pharmaceutical compositions on their basis and method for their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912225A IT1251161B (en) 1991-08-07 1991-08-07 QUATERNARY AMMONIUM DERIVATIVES OF (-) AND (+) - 3- (10 H-PHENOTHIAZIN-10-ILMETHYL) -L-AZABICYCLE (2.2.2.) OCT AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (3)

Publication Number Publication Date
ITMI912225A0 true ITMI912225A0 (en) 1991-08-07
ITMI912225A1 ITMI912225A1 (en) 1993-02-08
IT1251161B IT1251161B (en) 1995-05-04

Family

ID=11360550

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI912225A IT1251161B (en) 1991-08-07 1991-08-07 QUATERNARY AMMONIUM DERIVATIVES OF (-) AND (+) - 3- (10 H-PHENOTHIAZIN-10-ILMETHYL) -L-AZABICYCLE (2.2.2.) OCT AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (19)

Country Link
EP (1) EP0599896A1 (en)
JP (1) JPH06509570A (en)
CN (1) CN1071667A (en)
AU (1) AU2417392A (en)
BG (1) BG98439A (en)
BR (1) BR9206339A (en)
CA (1) CA2114844A1 (en)
CZ (1) CZ24894A3 (en)
EC (1) ECSP920859A (en)
FI (1) FI940530A (en)
HU (1) HUT66570A (en)
IT (1) IT1251161B (en)
MA (1) MA22611A1 (en)
MX (1) MX9204539A (en)
PT (1) PT100765A (en)
SK (1) SK11594A3 (en)
TN (1) TNSN92073A1 (en)
WO (1) WO1993003029A1 (en)
ZA (1) ZA925852B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1216353C (en) * 1996-10-18 2005-08-24 雅马哈株式会社 Music teaching system, method and storing media for performing programme
US20050220888A1 (en) * 2002-01-31 2005-10-06 Lakahmi Putcha Controlled release compositions and methods for using same
FR2910814B1 (en) * 2006-12-28 2011-06-17 Pf Medicament USE OF 10- (R3) -1-AZABICYCLO2.2.2-OCT-3-YLMETHYL-10H-PHENOTHIAZINE FOR THE PREPARATION OF A MEDICAMENT EXERCISING SELECTIVE INHIBITION OF M1,2,3 MUSCARINIC RECEPTORS
FR2911606B1 (en) * 2007-01-18 2009-04-17 Pierre Fabre Medicament Sa NEW QUINUCLIDINE DERIVATIVE USEFUL IN THE PREPARATION OF MEQUITAZINE
FR2924344B1 (en) * 2007-12-04 2010-04-16 Pf Medicament USE OF MEQUITAZINE IN THE FORM OF RACEMATE OR ENANTIOMERS FOR THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OR PREVENTION OF PATHOLOGIES INVOLVING HISTAMIC RECEPTORS H4.
FR2970255B1 (en) 2011-01-10 2013-09-06 Pf Medicament VINYL QUINUCLIDINE USEFUL AS A SYNTHETIC INTERMEDIARY IN THE PREPARATION OF (R) -MEQUITAZINE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2522660A1 (en) * 1982-03-05 1983-09-09 Pharmuka Lab MEQUITAZINE LEVOGYER ISOMER, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME
FR2526433B1 (en) * 1982-05-04 1985-10-18 Pharmuka Lab DEXTROGYRIC ISOMERS OF AZA-1 BICYCLO (2,2,2) OCTANE DERIVATIVES, THEIR PREPARATION METHOD AND MEDICAMENTS CONTAINING THEM
IT1173445B (en) * 1984-03-16 1987-06-24 Guidotti & C Spa Labor AGENTS WITH ANTIBRONCOSPASTIC ACTIVITY AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM

Also Published As

Publication number Publication date
ECSP920859A (en) 1993-08-03
BR9206339A (en) 1994-11-08
CN1071667A (en) 1993-05-05
HU9400273D0 (en) 1994-05-30
JPH06509570A (en) 1994-10-27
AU2417392A (en) 1993-03-02
IT1251161B (en) 1995-05-04
FI940530A0 (en) 1994-02-04
CZ24894A3 (en) 1994-07-13
PT100765A (en) 1993-10-29
EP0599896A1 (en) 1994-06-08
TNSN92073A1 (en) 1993-06-08
BG98439A (en) 1994-09-30
ZA925852B (en) 1993-03-05
MX9204539A (en) 1993-02-01
HUT66570A (en) 1994-12-28
SK11594A3 (en) 1994-12-07
MA22611A1 (en) 1993-04-01
WO1993003029A1 (en) 1993-02-18
FI940530A (en) 1994-02-04
ITMI912225A1 (en) 1993-02-08
CA2114844A1 (en) 1993-02-18

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970828