ITMI20121996A1 - WATER EXTRACT FOR BURNS TREATMENT - Google Patents

WATER EXTRACT FOR BURNS TREATMENT Download PDF

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Publication number
ITMI20121996A1
ITMI20121996A1 IT001996A ITMI20121996A ITMI20121996A1 IT MI20121996 A1 ITMI20121996 A1 IT MI20121996A1 IT 001996 A IT001996 A IT 001996A IT MI20121996 A ITMI20121996 A IT MI20121996A IT MI20121996 A1 ITMI20121996 A1 IT MI20121996A1
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IT
Italy
Prior art keywords
wild
extract
cistus
helichrysum
extract according
Prior art date
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IT001996A
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Italian (it)
Inventor
Bruno Alberto Chessa
Irene Chessa
Original Assignee
Bruno Alberto Chessa
Irene Chessa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Bruno Alberto Chessa, Irene Chessa filed Critical Bruno Alberto Chessa
Priority to IT001996A priority Critical patent/ITMI20121996A1/en
Publication of ITMI20121996A1 publication Critical patent/ITMI20121996A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Physical Water Treatments (AREA)

Description

Descrizione del brevetto per invenzione industriale avente per titolo: Description of the patent for industrial invention entitled:

“ESTRATTO ACQUOSO PER IL TRATTAMENTO DELLE USTIONI†⠀ œWATER EXTRACT FOR THE TREATMENT OF BURNSâ €

Campo dell’invenzione Field of invention

La presente invenzione riguarda un estratto acquoso di Camomilla selvatica, Cisto marino, Trifoglio selvatico, Prezzemolo, Elicriso utile nel trattamento delle ustioni. The present invention relates to an aqueous extract of wild chamomile, sea cistus, wild clover, parsley, helichrysum useful in the treatment of burns.

Stato dell’arte State of the art

La Camomilla selvatica (Matricaria chamomilla L.) Ã ̈ una pianta erbacea annuale appartenente della famiglia delle Asteraceae. Wild Chamomile (Matricaria chamomilla L.) is an annual herbaceous plant belonging to the Asteraceae family.

La Camomilla à ̈ nota per le sue proprietà antinfiammatorie, digestive, toniche, sedative, antinevralgiche. Chamomile is known for its anti-inflammatory, digestive, tonic, sedative, anti-neuralgic properties.

Il Cisto marino (Cistus monspeliensis L.) Ã ̈ un arbusto appartenente alla famiglia delle Cistaceae. The marine cistus (Cistus monspeliensis L.) is a shrub belonging to the Cistaceae family.

Dal Cisto marino viene normalmente estratta una resina chiamata ladano che trova impiego principalmente in profumeria dove viene utilizzata come fissativo. A resin called ladano is normally extracted from the marine cistus and is mainly used in perfumery where it is used as a fixative.

Il Trifoglio selvatico (Trifolium campestre) Ã ̈ una pianta erbacea appartenete alla famiglia Fabaceae (ovvero leguminose). The wild clover (Trifolium campestre) is a herbaceous plant belonging to the Fabaceae family (or legumes).

Dal trifoglio si possono estrarre ormoni vegetali, fitormoni, in particolare estrogeni, che si sono dimostrati utili nel rallentare l'invecchiamento della cute e delle mucose. Tali ormoni si sono inoltre dimostrati efficaci nel trattamento dei disturbi tipici associati alla menopausa, quali vampate, depressione, osteoporosi, malattie cardiovascolari. Recentemente, gli ormoni estratti dal trifoglio si sono rivelati utili anche contro l’ipertrofia prostatica. Vegetable hormones, phytohormones, in particular estrogens, can be extracted from clover, which have been shown to be useful in slowing the aging of the skin and mucous membranes. These hormones have also proved effective in the treatment of typical disorders associated with menopause, such as hot flashes, depression, osteoporosis, cardiovascular diseases. Recently, the hormones extracted from clover have also proved useful against prostatic hypertrophy.

Il Prezzemolo (Petroselinum hortense) Ã ̈ una pianta che appartiene alla famiglia delle Ombrellifere. Parsley (Petroselinum hortense) is a plant that belongs to the Umbelliferae family.

Principalmente il prezzemolo viene impiegato come diuretico, depurativo ed aforetico (le radici), emmenagogo (i semi), antisettico e antispasmodico. Mainly parsley is used as a diuretic, purifying and aphoretic (the roots), emmenagogue (the seeds), antiseptic and antispasmodic.

L'impacco di foglie pestate può essere usato per lenire punture di insetti, contusioni e mal di denti. The crushed leaf pack can be used to soothe insect bites, bruises and toothaches.

L’Elicriso (Helichrysum italicum L.) à ̈ una pianta appartenente alla famiglia delle Asteraceae. Helichrysum (Helichrysum italicum L.) is a plant belonging to the Asteraceae family.

Viene utilizzato come sedativo, bechico e stimolante della circolazione sanguigna. It is used as a sedative, bechico and stimulant of blood circulation.

Sussiste la necessità di individuare preparazioni utili nel trattamento topico in particolare delle ustioni. There is a need to identify preparations useful in the topical treatment of burns in particular.

Sommario dell’invenzione Summary of the invention

La presente invenzione à ̈ relativa a un estratto acquoso di una composizione comprendente: The present invention relates to an aqueous extract of a composition comprising:

a) Camomilla selvatica, a) Wild chamomile,

b) Cisto marino, b) Sea cistus,

c) Trifoglio selvatico, c) Wild clover,

d) Prezzemolo, d) Parsley,

e) Elicriso. e) Helichrysum.

L’invenzione si riferisce inoltre all’uso dell’estratto acquoso come medicamento. The invention also refers to the use of the aqueous extract as a medicine.

Descrizione dell’invenzione Description of the invention

Si à ̈ sorprendentemente trovato che un estratto acquoso di Camomilla selvatica, Cisto marino, Trifoglio selvatico, Prezzemolo e Elicriso à ̈ utile nel trattamento topico delle ustioni. Surprisingly, an aqueous extract of Wild Chamomile, Sea Cistus, Wild Clover, Parsley and Helichrysum has been found to be useful in the topical treatment of burns.

Pertanto la presente invenzione à ̈ relativa a un estratto acquoso di una composizione consistente nelle seguenti piante: Therefore the present invention relates to an aqueous extract of a composition consisting of the following plants:

a) Camomilla selvatica (Matricaria chamomilla L.), a) Wild chamomile (Matricaria chamomilla L.),

b) Cisto marino (Cistus monspeliensis L.), b) Marine cistus (Cistus monspeliensis L.),

c) Trifoglio selvatico (Trifolium campestre), c) Wild clover (Trifolium campestre),

d) Prezzemolo (Petroselinum hortense), d) Parsley (Petroselinum hortense),

e) Elicriso (Helichrysum italicum L.). e) Helichrysum (Helichrysum italicum L.).

Secondo un aspetto preferito dell’invenzione, le piante possono essere presenti nelle composizioni entro i seguenti intervalli in peso preferiti: According to a preferred aspect of the invention, plants can be present in the compositions within the following preferred weight ranges:

a) Camomilla selvatica da 450 g a 600 g, a) Wild chamomile from 450g to 600g,

b) Cisto marino da 700 g a 800 g, b) Marine cistus from 700 g to 800 g,

c) Trifoglio selvatico da 450 g a 600 g, c) Wild clover from 450g to 600g,

d) Prezzemolo da 450 g a 600 g, d) Parsley from 450 g to 600 g,

e) Elicriso da 700 g a 800 g. e) Helichrysum from 700 g to 800 g.

Secondo un aspetto particolarmente preferito dell’invenzione, le piante possono essere presenti nelle composizioni con le seguenti quantità in peso: According to a particularly preferred aspect of the invention, plants can be present in the compositions with the following quantities by weight:

a) Camomilla selvatica 500 g, a) Wild chamomile 500 g,

b) Cisto marino 750 g, b) Marine cistus 750 g,

c) Trifoglio selvatico 500 g, c) Wild clover 500 g,

d) Prezzemolo 500 g, d) Parsley 500 g,

e) Elicriso 750 g. e) Helichrysum 750 g.

L’estratto à ̈ preferibilmente un infuso o un decotto. The extract is preferably an infusion or a decoction.

L’estratto può essere preparato secondo tecniche convenzionali note; in particolare per infusione o per decozione, come previsto, ad esempio, dalla Farmacopea. The extract can be prepared according to known conventional techniques; in particular by infusion or by decoction, as required, for example, by the Pharmacopoeia.

L’estratto dell’invenzione si à ̈ dimostrato efficace nel trattamento topico delle ustioni. The extract of the invention has proven effective in the topical treatment of burns.

In particolare, secondo un aspetto dell’invenzione, le ustioni possono essere ustioni di primo grado, ustioni di secondo grado, ustioni di terzo grado. In particular, according to one aspect of the invention, burns can be first degree burns, second degree burns, third degree burns.

L’estratto secondo la presente invenzione consente, oltre al trattamento delle ustioni, di prevenire la formazione di cicatrici. The extract according to the present invention allows, in addition to the treatment of burns, to prevent the formation of scars.

Secondo un ulteriore aspetto dell’invenzione, l’estratto può essere utilizzato topicamente per il trattamento di abrasioni cutanee, e dell’Herpes zoster (fuoco di Sant’Antonio). According to a further aspect of the invention, the extract can be used topically for the treatment of skin abrasions, and Herpes zoster (St. Anthony's fire).

Si riporta di seguito un esempio che illustra ulteriormente l’invenzione. Below is an example that further illustrates the invention.

Esempio - Preparazione dell’estratto Example - Preparation of the extract

L’estratto può essere preparato a partire da una composizione costituita da: The extract can be prepared starting from a composition consisting of:

• Cisto marino 750 g, â € ¢ Marine cistus 750 g,

• Elicriso 750 g, â € ¢ Helichrysum 750 g,

• Camomilla selvatica 500 g, â € ¢ Wild chamomile 500 g,

• Trifoglio selvatico 500 g, â € ¢ Wild clover 500 g,

• Prezzemolo 500 g. â € ¢ Parsley 500 g.

Eccipienti: Excipients:

• Acqua 2 litri. â € ¢ Water 2 liters.

La composizione viene posta in acqua, si porta ad ebollizione e si mantiene ad ebollizione per 30 minuti a fuoco lento mescolando costantemente. The composition is placed in water, brought to a boil and kept at a boil for 30 minutes on low heat, stirring constantly.

Si lascia raffreddare. It is left to cool.

Il prodotto così ottenuto viene pressato con un torchio, il prodotto derivante viene filtrato a dare l’estratto di colore marroncino/verdastro. The product thus obtained is pressed with a press, the resulting product is filtered to give the extract of a brownish / greenish color.

Claims (9)

RIVENDICAZIONI 1. Estratto acquoso di una composizione consistente nelle seguenti piante: a) Camomilla selvatica (Matricaria chamomilla L.), b) Cisto marino (Cistus monspeliensis L.), c) Trifoglio selvatico (Trifolium campestre), d) Prezzemolo (Petroselinum hortense), e) Elicriso (Helichrysum italicum L.). CLAIMS 1. Aqueous extract of a composition consisting of the following plants: a) Wild chamomile (Matricaria chamomilla L.), b) Marine cistus (Cistus monspeliensis L.), c) Wild clover (Trifolium campestre), d) Parsley (Petroselinum hortense), e) Helichrysum (Helichrysum italicum L.). 2. Estratto secondo la rivendicazione 1, in cui dette piante variano entro i seguenti intervalli in peso: a) Camomilla selvatica da 450 g a 600 g, b) Cisto marino da 700 g a 800 g, c) Trifoglio selvatico da 450 g a 600 g, d) Prezzemolo da 450 g a 600 g, e) Elicriso da 700 g a 800 g. 2. Extract according to claim 1, wherein said plants vary within the following weight ranges: a) Wild chamomile from 450g to 600g, b) Marine cistus from 700 g to 800 g, c) Wild clover from 450g to 600g, d) Parsley from 450 g to 600 g, e) Helichrysum from 700 g to 800 g. 3. Estratto secondo le rivendicazioni 1 o 2, in cui la composizione consiste in: a) Camomilla selvatica 500 g, b) Cisto marino 750 g, c) Trifoglio selvatico 500 g, d) Prezzemolo 500 g, e) Elicriso 750 g. 3. Extract according to claims 1 or 2, wherein the composition consists of: a) Wild chamomile 500 g, b) Marine cistus 750 g, c) Wild clover 500 g, d) Parsley 500 g, e) Helichrysum 750 g. 4. Estratto secondo le rivendicazioni 1-3, per l’uso come medicamento. 4. Extract according to claims 1-3, for use as a medicament. 5. Estratto secondo le rivendicazioni 1-3, per l’uso topico nel trattamento di ustioni. 5. Extract according to claims 1-3, for topical use in the treatment of burns. 6. Estratto per l’uso secondo la rivendicazione 5, in cui le ustioni sono di primo, secondo o terzo grado. 6. Extract for use according to claim 5, wherein the burns are of first, second or third degree. 7. Estratto secondo le rivendicazioni 1-3, per l’uso topico nella prevenzione di cicatrici. 7. Extract according to claims 1-3, for topical use in the prevention of scars. 8. Estratto secondo le rivendicazioni 1-3, per l’uso topico nel trattamento di abrasioni cutanee. 8. Extract according to claims 1-3, for topical use in the treatment of skin abrasions. 9. Estratto secondo le rivendicazioni 1-3, per l’uso topico nel trattamento dell’Herpes zoster.9. Extract according to claims 1-3, for topical use in the treatment of Herpes zoster.
IT001996A 2012-11-23 2012-11-23 WATER EXTRACT FOR BURNS TREATMENT ITMI20121996A1 (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3135205A1 (en) * 2022-05-09 2023-11-10 Pierre Fabre Dermo-Cosmetique CISTUS MONSPELIENSIS EXTRACT AND COMPOSITIONS COMPRISING IT TO PROMOTE HEALING AND REPAIR OF SKIN LESIONS

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008053246A1 (en) * 2006-10-30 2008-05-08 Reckitt & Colman (Overseas) Limited Acne treatment
WO2010145655A1 (en) * 2009-06-19 2010-12-23 Rexcure V/Jan Enggaard Herbal extract composition comprising petroselinum and ocimum extract
WO2012033422A1 (en) * 2010-09-06 2012-03-15 Aleksandar Pavlov Medical cosmetic herbal composition on the basis of herbal mixture and the procedure for its obtention

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008053246A1 (en) * 2006-10-30 2008-05-08 Reckitt & Colman (Overseas) Limited Acne treatment
WO2010145655A1 (en) * 2009-06-19 2010-12-23 Rexcure V/Jan Enggaard Herbal extract composition comprising petroselinum and ocimum extract
WO2012033422A1 (en) * 2010-09-06 2012-03-15 Aleksandar Pavlov Medical cosmetic herbal composition on the basis of herbal mixture and the procedure for its obtention

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
AMIR HOSSEIN ABDOLGHAFFARI ET AL: "Wound healing effect of Rosemary and Chamomile combination in rat", PHARMACOLOGYONLINE, vol. 3, 1 January 2010 (2010-01-01), pages 139 - 145, XP055055842 *
F. ARANITI ET AL: "Screening of Mediterranean wild plant species for allelopathic activity and their use as bio-herbicides", ALLELOPATHY JOURNAL, vol. 29, no. 1, 1 January 2012 (2012-01-01), pages 107 - 124, XP055055827 *
SALA A ET AL: "ANTI-INFLAMMATORY AND ANTIOXIDANT PROPERTIES OF HELICHRYSUM ITALICUM", JOURNAL OF PHARMACY AND PHARMACOLOGY, JOHN WILEY & SONS LTD, LONDON; GB, vol. 54, no. 3, 1 March 2002 (2002-03-01), pages 365 - 371, XP008025203, ISSN: 0022-3573, DOI: 10.1211/0022357021778600 *
WU Q ET AL: "Determination of isoflavones in red clover and related species by high-performance liquid chromatography combined with ultraviolet and mass spectrometric detection", JOURNAL OF CHROMATOGRAPHY, ELSEVIER SCIENCE PUBLISHERS B.V, NL, vol. 1016, no. 2, 24 October 2003 (2003-10-24), pages 195 - 209, XP004458187, ISSN: 0021-9673, DOI: 10.1016/J.CHROMA.2003.08.001 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3135205A1 (en) * 2022-05-09 2023-11-10 Pierre Fabre Dermo-Cosmetique CISTUS MONSPELIENSIS EXTRACT AND COMPOSITIONS COMPRISING IT TO PROMOTE HEALING AND REPAIR OF SKIN LESIONS
EP4275695A1 (en) * 2022-05-09 2023-11-15 Pierre Fabre Dermo-Cosmétique Cistus monspeliensis extract and compositions comprising same for promoting wound healing and repair of skin lesions

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