ITMI20020146A1 - AMORPHOUS MONOSODIUM ALENDRONATE AND PROCESS FOR ITS PREPARATION - Google Patents

AMORPHOUS MONOSODIUM ALENDRONATE AND PROCESS FOR ITS PREPARATION

Info

Publication number
ITMI20020146A1
ITMI20020146A1 IT2002MI000146A ITMI20020146A ITMI20020146A1 IT MI20020146 A1 ITMI20020146 A1 IT MI20020146A1 IT 2002MI000146 A IT2002MI000146 A IT 2002MI000146A IT MI20020146 A ITMI20020146 A IT MI20020146A IT MI20020146 A1 ITMI20020146 A1 IT MI20020146A1
Authority
IT
Italy
Prior art keywords
preparation
monosodium alendronate
amorphous monosodium
amorphous
alendronate
Prior art date
Application number
IT2002MI000146A
Other languages
Italian (it)
Inventor
Simona Grassi
Anna Volante
Original Assignee
Lyogen Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lyogen Ltd filed Critical Lyogen Ltd
Priority to IT2002MI000146A priority Critical patent/ITMI20020146A1/en
Publication of ITMI20020146A0 publication Critical patent/ITMI20020146A0/en
Priority to PCT/EP2002/007066 priority patent/WO2003064438A1/en
Publication of ITMI20020146A1 publication Critical patent/ITMI20020146A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
IT2002MI000146A 2002-01-29 2002-01-29 AMORPHOUS MONOSODIUM ALENDRONATE AND PROCESS FOR ITS PREPARATION ITMI20020146A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT2002MI000146A ITMI20020146A1 (en) 2002-01-29 2002-01-29 AMORPHOUS MONOSODIUM ALENDRONATE AND PROCESS FOR ITS PREPARATION
PCT/EP2002/007066 WO2003064438A1 (en) 2002-01-29 2002-06-26 Amorphous monosodium alendronate and preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2002MI000146A ITMI20020146A1 (en) 2002-01-29 2002-01-29 AMORPHOUS MONOSODIUM ALENDRONATE AND PROCESS FOR ITS PREPARATION

Publications (2)

Publication Number Publication Date
ITMI20020146A0 ITMI20020146A0 (en) 2002-01-29
ITMI20020146A1 true ITMI20020146A1 (en) 2003-07-29

Family

ID=11449012

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2002MI000146A ITMI20020146A1 (en) 2002-01-29 2002-01-29 AMORPHOUS MONOSODIUM ALENDRONATE AND PROCESS FOR ITS PREPARATION

Country Status (2)

Country Link
IT (1) ITMI20020146A1 (en)
WO (1) WO2003064438A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2172192A1 (en) 2001-12-24 2010-04-07 Teva Pharmaceutical Industries Ltd. Dosage form with a core tablet of active ingredient sheathed in a compressed annular body of powder of granular material, and process and tooling for producing it
CZ297262B6 (en) * 2004-12-28 2006-10-11 Zentiva, A. S. Trisodium salt of 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4922007A (en) * 1989-06-09 1990-05-01 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof
DK0833643T3 (en) * 1995-06-06 2005-05-30 Merck & Co Inc Formulations of anhydrous monosodium salt of alendronate and their use in the treatment of bone disorders
IL141423A (en) * 1998-08-27 2005-09-25 Teva Pharma Hydrate forms of alendronate sodium, processes for manufacture thereof, and pharmaceutical compositions thereof
WO2000034293A1 (en) * 1998-12-10 2000-06-15 Aesgen, Inc. Method for preparation of disodium pamidronate
GB2383042A (en) * 2001-10-18 2003-06-18 Cipla Ltd Amorphous alendronate sodium

Also Published As

Publication number Publication date
ITMI20020146A0 (en) 2002-01-29
WO2003064438A1 (en) 2003-08-07

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