ITLE20130014A1 - COMPOSITION FOR SOOTHING CREAM - Google Patents
COMPOSITION FOR SOOTHING CREAMInfo
- Publication number
- ITLE20130014A1 ITLE20130014A1 IT000014A ITLE20130014A ITLE20130014A1 IT LE20130014 A1 ITLE20130014 A1 IT LE20130014A1 IT 000014 A IT000014 A IT 000014A IT LE20130014 A ITLE20130014 A IT LE20130014A IT LE20130014 A1 ITLE20130014 A1 IT LE20130014A1
- Authority
- IT
- Italy
- Prior art keywords
- cream
- itching
- intimate
- symptoms
- treatment
- Prior art date
Links
- 239000006071 cream Substances 0.000 title claims description 13
- 239000000203 mixture Substances 0.000 title description 3
- 208000003251 Pruritus Diseases 0.000 claims description 25
- 230000007803 itching Effects 0.000 claims description 19
- 238000011282 treatment Methods 0.000 claims description 9
- 208000024891 symptom Diseases 0.000 claims description 8
- 239000000739 antihistaminic agent Substances 0.000 claims description 5
- FUFLCEKSBBHCMO-UHFFFAOYSA-N 11-dehydrocorticosterone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)C(=O)CO)C4C3CCC2=C1 FUFLCEKSBBHCMO-UHFFFAOYSA-N 0.000 claims description 3
- MFYSYFVPBJMHGN-ZPOLXVRWSA-N Cortisone Chemical compound O=C1CC[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 MFYSYFVPBJMHGN-ZPOLXVRWSA-N 0.000 claims description 3
- MFYSYFVPBJMHGN-UHFFFAOYSA-N Cortisone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)(O)C(=O)CO)C4C3CCC2=C1 MFYSYFVPBJMHGN-UHFFFAOYSA-N 0.000 claims description 3
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 claims description 3
- 230000003444 anaesthetic effect Effects 0.000 claims description 3
- 230000001387 anti-histamine Effects 0.000 claims description 3
- 229960004544 cortisone Drugs 0.000 claims description 3
- 239000004480 active ingredient Substances 0.000 claims description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 4
- KBPLFHHGFOOTCA-UHFFFAOYSA-N 1-Octanol Chemical compound CCCCCCCCO KBPLFHHGFOOTCA-UHFFFAOYSA-N 0.000 claims 2
- 235000004433 Simmondsia californica Nutrition 0.000 claims 2
- 241000221096 Simmondsia chinensis Species 0.000 claims 2
- 229930003427 Vitamin E Natural products 0.000 claims 2
- 235000004417 Zanthoxylum alatum Nutrition 0.000 claims 2
- 241001227724 Zanthoxylum planispinum Species 0.000 claims 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 235000015112 vegetable and seed oil Nutrition 0.000 claims 2
- 229940046009 vitamin E Drugs 0.000 claims 2
- 235000019165 vitamin E Nutrition 0.000 claims 2
- 239000011709 vitamin E Substances 0.000 claims 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims 1
- 150000005690 diesters Chemical class 0.000 claims 1
- TVWTZAGVNBPXHU-NXVVXOECSA-N dioctyl (z)-but-2-enedioate Chemical compound CCCCCCCCOC(=O)\C=C/C(=O)OCCCCCCCC TVWTZAGVNBPXHU-NXVVXOECSA-N 0.000 claims 1
- 239000003974 emollient agent Substances 0.000 claims 1
- 229940119170 jojoba wax Drugs 0.000 claims 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 1
- 239000011976 maleic acid Substances 0.000 claims 1
- 230000003020 moisturizing effect Effects 0.000 claims 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 1
- 239000010497 wheat germ oil Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 description 4
- 230000035807 sensation Effects 0.000 description 3
- 206010012442 Dermatitis contact Diseases 0.000 description 2
- 206010015150 Erythema Diseases 0.000 description 2
- 206010017533 Fungal infection Diseases 0.000 description 2
- 229940125715 antihistaminic agent Drugs 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 208000010247 contact dermatitis Diseases 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000002458 infectious effect Effects 0.000 description 2
- 230000011514 reflex Effects 0.000 description 2
- 206010012335 Dependence Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 description 1
- 206010024434 Lichen sclerosus Diseases 0.000 description 1
- 208000019914 Mental Fatigue Diseases 0.000 description 1
- 201000009053 Neurodermatitis Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010033733 Papule Diseases 0.000 description 1
- 201000004681 Psoriasis Diseases 0.000 description 1
- 206010037549 Purpura Diseases 0.000 description 1
- 206010070834 Sensitisation Diseases 0.000 description 1
- 206010040799 Skin atrophy Diseases 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 229940035674 anesthetics Drugs 0.000 description 1
- 230000003542 behavioural effect Effects 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 230000035614 depigmentation Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 238000004299 exfoliation Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 239000003193 general anesthetic agent Substances 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000020082 intraepithelial neoplasia Diseases 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000004126 nerve fiber Anatomy 0.000 description 1
- 239000004096 non-sedating histamine H1 antagonist Substances 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 206010034754 petechiae Diseases 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000006748 scratching Methods 0.000 description 1
- 230000002393 scratching effect Effects 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 210000003009 spinothalamic tract Anatomy 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Description
Descrizione del Brevetto per Invenzione Industriale avente per titolo: “Composizione per crema Lenitiva” Description of the Patent for Industrial Invention entitled: "Composition for soothing cream"
DESCRIZIONE DESCRIPTION
Il prurito è una sensazione che provoca il desiderio o il riflesso di grattarsi. Attualmente è stato dimostrato che esso possiede molte somiglianze con il dolore, e mentre entrambe sono esperienze sensoriali spiacevoli, i loro modelli comportamentali di risposta sono diversi, li dolore crea un riflesso di ritiro, mentre il prurito porta al grattarsi. Itching is a sensation that causes the urge or reflex to scratch. Currently it has been shown that it has many similarities to pain, and while both are unpleasant sensory experiences, their behavioral patterns of response are different, pain creates a withdrawal reflex, while itching leads to scratching.
Entrambe le fibre nervose arnieliniche deputate a rilevare il prurito e il dolore hanno origine nella pelle. T uttavia, le loro informazioni vengono trasferite ai sistema nervoso centrale attraverso due distinti sistemi che utilizzano entrambi gli stessi fasci nervosi e il tratto spinotalamico. Il prurito intimo è un sintomo molto fastidioso che può colpire sia in età adulta che in età pediatrica. Both arnielin nerve fibers responsible for detecting itching and pain originate in the skin. However, their information is transferred to the central nervous system through two distinct systems that use both the same nerve bundles and the spinothalamic tract. Intimate itching is a very annoying symptom that can affect both adults and children.
Le cause del prurito intimo possono essere classificate in: The causes of intimate itching can be classified into:
-cause di origine infettiva; -causes of infectious origin;
-cause di origine non infettiva; -causes of non-infectious origin;
Una terza tipologia è il prurito intimo classificato come idiomatico o “sine materia”. A third type is the intimate itch classified as idiomatic or "sine materia".
In questi casi esso non è riconducibile a nessuna delle due cause precedenti. Il prurito, a seconda della ricorrenza, è classificato in: In these cases it cannot be traced back to either of the two preceding causes. Itching, depending on the recurrence, is classified into:
-Acuto (il prurito intimo si manifesta con attacchi molto intensi ma brevi). Questa tipologia di prurito è tipica delle infezioni da lieviti e delle dermatiti da contatto. -Cronico (il prurito intimo è duraturo e continuo). Tipico di patologie come il Lichen Scleroso, il Lichen Planus, il Lichen Simplex, la Psoriasi o la Neoplasia Intraepiteliale. -Ricorrente (il prurito intimo si interrompe per dei periodi di tempo e poi si ripresenta). Tipico di problematiche come infezioni da lieviti, dermatiti da contatto, herpes, dermatosi infiammatorie o reazioni all'uso di droghe. -Acute (intimate itching occurs with very intense but short attacks). This type of itch is typical of yeast infections and contact dermatitis. -Chronic (intimate itching is long-lasting and continuous). Typical of pathologies such as Lichen Sclerosus, Lichen Planus, Lichen Simplex, Psoriasis or Intraepithelial Neoplasia. -Recurrent (intimate itching stops for periods of time and then returns). Typical of problems such as yeast infections, contact dermatitis, herpes, inflammatory dermatoses or reactions to drug use.
La sensazione di prurito è molto ricorrente nelle zone intime, sia di uomini che di donne. Questa sensazione può avere diversa eziologia come sopra descritto e oltre a comportare fastidio, scatena una serie di reazioni (prurito-grattare-prurito...) che innescano dei processi infiammatori con conseguenti stati di bruciore e arrossamento che condizionano in maniera negativa il benessere della persona, e di conseguenza del proprio partner, a causa della scarsa qualità dei rapporti sessuali che ne possono derivare. The sensation of itching is very recurrent in the intimate areas, both of men and women. This sensation can have different etiology as described above and in addition to causing discomfort, it triggers a series of reactions (itch-scratch-itch ...) that trigger inflammatory processes with consequent states of burning and redness that negatively affect the well-being of the person, and consequently of one's partner, due to the poor quality of sexual relations that can result from it.
I normali trattamenti consigliati in ginecologia consistono di forme farmaceutiche (spray, creme, gel, polveri) a base di molecole antistaminiche, anestetiche e cortisoniche mirate a combattere il prurito e le conseguenze che ne derivano, sopra descritte. Questi trattamenti comportano una serie di effetti collaterali come fenomeni irritativi e di sensibilizzazione, atrofia cutanea, acne steroidea, e altri. The normal treatments recommended in gynecology consist of pharmaceutical forms (sprays, creams, gels, powders) based on antihistamine, anesthetic and cortisone molecules aimed at combating itching and the resulting consequences, described above. These treatments involve a number of side effects such as irritation and sensitization phenomena, skin atrophy, steroid acne, and others.
Le molecole antistaminiche invece hanno una serie di effetti collaterali (capogiro, sonnolenza, stanchezza mentale); questi effetti sono stati quasi del tutto eliminati attraverso il progresso della scienza (antistaminici di seconda generazione) e sono comunque minimi in prodotti per uso topico. Sono segnalati molti casi di assuefazione e dipendenza da farmaci antistaminici. The antihistamine molecules, on the other hand, have a series of side effects (dizziness, drowsiness, mental fatigue); these effects have been almost completely eliminated through the progress of science (second generation antihistamines) and are still minimal in topical products. Many cases of addiction and dependence on antihistamines are reported.
Le molecole con proprietà anestetiche invece posseggono un’ alta percentuale di probabilità che si verifichino degli effetti collaterali sulla cute. I più tipici e frequenti sono: depigmentazione, dermatite, prurito, bruciore, eritema, edema, comparsa di papule e vescicole, esfoliazione e petecchie. Molecules with anesthetic properties, on the other hand, have a high percentage of probability that side effects will occur on the skin. The most typical and frequent are: depigmentation, dermatitis, itching, burning, erythema, edema, appearance of papules and vesicles, exfoliation and petechiae.
Attualmente la ricerca di soluzioni naturali per il trattamento della sintomatologia sta riscuotendo enorme interesse nelle principali case farmaceutiche mondiali, proprio per limitare l’eccessivo uso di farmaci cortisonici, antistaminici e anestetici. Currently, the search for natural solutions for the treatment of symptoms is arousing enormous interest in the world's leading pharmaceutical companies, precisely to limit the excessive use of cortisone drugs, antihistamines and anesthetics.
Scopo della presente invenzione è dunque l'ideazione e la formulazione di una crema a base di una combinazione di attivi di derivazione naturale con spiccate caratteristiche anti-prurito. In particolare è stato utilizzato: The aim of the present invention is therefore the design and formulation of a cream based on a combination of naturally derived active ingredients with marked anti-itch characteristics. In particular, it was used:
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000014A ITLE20130014A1 (en) | 2013-09-26 | 2013-09-26 | COMPOSITION FOR SOOTHING CREAM |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000014A ITLE20130014A1 (en) | 2013-09-26 | 2013-09-26 | COMPOSITION FOR SOOTHING CREAM |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITLE20130014A1 true ITLE20130014A1 (en) | 2015-03-27 |
Family
ID=50073283
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT000014A ITLE20130014A1 (en) | 2013-09-26 | 2013-09-26 | COMPOSITION FOR SOOTHING CREAM |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | ITLE20130014A1 (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010002260A1 (en) * | 1998-07-07 | 2001-05-31 | Ezio Bombardelli | Extracts of zanthoxylum bungeanum, and pharmaceutical and cosmetic formulations containing same |
| US20030157196A1 (en) * | 2002-02-19 | 2003-08-21 | Bartels Jennifer F. | Compositions and methods for creating an air release mechanism to maintain skin health |
| US20050203187A1 (en) * | 1998-06-01 | 2005-09-15 | Verbiscar Anthony J. | Formulations useful for the treatment of varicella zoster virus infections and methods for the use thereof |
| JP2012240971A (en) * | 2011-05-20 | 2012-12-10 | Kyoei Kagaku Kogyo Kk | Cosmetic |
-
2013
- 2013-09-26 IT IT000014A patent/ITLE20130014A1/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050203187A1 (en) * | 1998-06-01 | 2005-09-15 | Verbiscar Anthony J. | Formulations useful for the treatment of varicella zoster virus infections and methods for the use thereof |
| US20010002260A1 (en) * | 1998-07-07 | 2001-05-31 | Ezio Bombardelli | Extracts of zanthoxylum bungeanum, and pharmaceutical and cosmetic formulations containing same |
| US20030157196A1 (en) * | 2002-02-19 | 2003-08-21 | Bartels Jennifer F. | Compositions and methods for creating an air release mechanism to maintain skin health |
| JP2012240971A (en) * | 2011-05-20 | 2012-12-10 | Kyoei Kagaku Kogyo Kk | Cosmetic |
Non-Patent Citations (2)
| Title |
|---|
| "New Learnings on the Clinical Benefits of", 1 October 2012 (2012-10-01), XP055105064, Retrieved from the Internet <URL:http://www.the-dermatologist.com/sites/default/files/Aveeno_Insert_Oct2012_0.pdf> [retrieved on 20140303] * |
| OAT CP ET AL: "Application Benefits Ingredient Properties Oat (Avena sativa) Extract 3%", 24 February 2012 (2012-02-24), XP055105069, Retrieved from the Internet <URL:http://www.protecingredia.com/products/oatcosmetics/cp-oat-avenanthramides-tds-2012-02-24.pdf> [retrieved on 20140303] * |
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