ITFI20100160A1 - COMPOSITION FOR THE TREATMENT OF RAGADI. - Google Patents
COMPOSITION FOR THE TREATMENT OF RAGADI. Download PDFInfo
- Publication number
- ITFI20100160A1 ITFI20100160A1 IT000160A ITFI20100160A ITFI20100160A1 IT FI20100160 A1 ITFI20100160 A1 IT FI20100160A1 IT 000160 A IT000160 A IT 000160A IT FI20100160 A ITFI20100160 A IT FI20100160A IT FI20100160 A1 ITFI20100160 A1 IT FI20100160A1
- Authority
- IT
- Italy
- Prior art keywords
- composition
- treatment
- nitrocellulose
- castor oil
- tocopherol
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims description 14
- 239000000020 Nitrocellulose Substances 0.000 claims description 7
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 7
- 229920001220 nitrocellulos Polymers 0.000 claims description 7
- 239000004359 castor oil Substances 0.000 claims description 6
- 235000019438 castor oil Nutrition 0.000 claims description 6
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 6
- 229930003799 tocopherol Natural products 0.000 claims description 5
- 229960001295 tocopherol Drugs 0.000 claims description 5
- 239000011732 tocopherol Substances 0.000 claims description 5
- 235000010384 tocopherol Nutrition 0.000 claims description 5
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 5
- 239000000126 substance Substances 0.000 claims description 4
- 210000003371 toe Anatomy 0.000 claims description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims 3
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 1
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 claims 1
- 235000019441 ethanol Nutrition 0.000 claims 1
- 235000019439 ethyl acetate Nutrition 0.000 claims 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 1
- 229940042585 tocopherol acetate Drugs 0.000 claims 1
- 210000003491 skin Anatomy 0.000 description 6
- 230000035876 healing Effects 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 3
- 239000010410 layer Substances 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000016571 aggressive behavior Effects 0.000 description 2
- 210000002683 foot Anatomy 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- LQIAZOCLNBBZQK-UHFFFAOYSA-N 1-(1,2-Diphosphanylethyl)pyrrolidin-2-one Chemical compound PCC(P)N1CCCC1=O LQIAZOCLNBBZQK-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 239000003570 air Substances 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000004899 motility Effects 0.000 description 1
- 230000008058 pain sensation Effects 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 230000037390 scarring Effects 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/717—Celluloses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Description
DESCRIZIONE DESCRIPTION
La presente invenzione riguarda una composizione per il trattamento delle ragadi e, più in particolare, per il trattamento delle ragadi delle dita di mani e piedi. The present invention relates to a composition for the treatment of fissures and, more particularly, for the treatment of fissures of the fingers and toes.
E’ noto che le ragadi sono costituite da piccole fessure che interessano repidermide e parte del derma, estendendosi talvolta fino airipoderma. Esse possono coinvolgere le dita delle mani e dei piedi a seguito di aggressioni da agenti climatici come freddo ed eccessivi livelli di umidità o calore, da sfregamento o da agenti chimici, come ad esempio alcool e saponi, o per effetto di traumi, che provocano perdita di elasticità, ispessimento e spesso rottura della pelle. It is known that fissures are made up of small cracks affecting the repidermis and part of the dermis, sometimes extending to the airipodermis. They can involve the fingers and toes as a result of aggression from climatic agents such as cold and excessive levels of humidity or heat, from rubbing or from chemical agents, such as alcohol and soaps, or as a result of trauma, which cause loss of elasticity, thickening and often breakage of the skin.
E’ altresì noto che il trattamento di screpolature della pelle e ragadi normalmente prevede l’uso di creme che idratano e ammorbidiscono la pelle ma che sono più indicate a scopo preventivo giacché non evitano la riapertura della lesione e non leniscono il dolore. It is also known that the treatment of skin cracks and fissures normally involves the use of creams that moisturize and soften the skin but which are more suitable for preventive purposes as they do not prevent the reopening of the lesion and do not soothe the pain.
Lo scopo principale della presente invenzione è quello di proporre una composizione vantaggiosamente utilizzabile per il trattamento delle ragadi, e in particolare quelle che interessano le dita delle mani e dei piedi, eliminando o quantomeno riducendo sensibilmente gli inconvenienti sopra menzionati. A questo risultato si è pervenuti, in conformità della presente invenzione, adottando l’idea di realizzare una composizione avente le caratteristiche indicate nella rivendicazione 1. Altre caratteristiche della presente invenzione sono oggetto delle rivendicazioni dipendenti. The main object of the present invention is to propose a composition which can be advantageously used for the treatment of fissures, and in particular those affecting the fingers and toes, eliminating or at least significantly reducing the aforementioned drawbacks. This result has been achieved, in accordance with the present invention, by adopting the idea of making a composition having the characteristics indicated in claim 1. Other characteristics of the present invention are the subject of the dependent claims.
Una composizione in conformità della presente invenzione è utilizzabile per il trattamento di tutti i tipi di ragadi che interessano le mani e i piedi, qualunque ne sia la posizione, favorisce la cicatrizzazione, elimina il dolore, è pronto all’uso, è applicabile localmente sulla ragade, presenta ottimali caratteristiche di penetrabilità internamente alla ragade, ed asciuga rapidamente lasciando un film protettivo evidente. A composition in accordance with the present invention can be used for the treatment of all types of fissures affecting the hands and feet, whatever their position, promotes scarring, eliminates pain, is ready to use, is applicable locally on the fissure , has excellent characteristics of penetrability inside the fissure, and dries quickly, leaving an evident protective film.
Questi ed ulteriori vantaggi e caratteristiche della presente invenzione saranno più e meglio compresi da ogni tecnico del ramo grazie alla descrizione che segue, nella quale sono indicati possibili esempi di realizzazione del trovato da non intendersi in senso limitativo. These and further advantages and characteristics of the present invention will be better understood by every person skilled in the art thanks to the following description, in which possible embodiments of the invention are indicated, not to be understood in a limiting sense.
Una possibile formulazione della composizione in oggetto prevede i seguenti componenti: A possible formulation of the composition in question includes the following components:
In particolare, la fase solvente assicura dissoluzione della nitrocellulosa. In conformità di una forma preferita di attuazione dell’invenzione, la formulazione della composizione è la seguente: In particular, the solvent phase ensures dissolution of the nitrocellulose. In accordance with a preferred embodiment of the invention, the formulation of the composition is as follows:
La composizione si presenta in forma di gel ed è indicata nel trattamento delle piccole ragadi, delle screpolature, delle fissurazioni, delle spaccature dei piedi e delle mani e dei piccoli tagli che non sanguinano. Sotto il film che forma lo strato protettivo si mantiene Γ idratazione della cute che, pertanto, guarisce “in ambiente umido”. Il processo di guarigione è favorito sia dal mantenimento dell’ ambiente umido che dalla vitamina E contenuta nel prodotto applicato sulla ragade. Il film protettivo protegge la ragade dall’aggressione degli agenti esterni (come batteri, acqua, agenti termici e fisici), impedisce la riapertura della ragade, allevia il dolore e favorisce la cicatrizzazione. Il prodotto viene applicato, eventualmente con l’aiuto di una spatola, fino a colmare e ricoprire la ragade ed asciuga in qualche secondo. L’applicazione può essere rinnovata 2/3 volte al giorno fino alla cicatrizzazione completa. Normalmente il film si elimina da se dopo qualche tempo, con il normale lavaggio delle mani o con gli sfregamenti. In caso di bisogno, il film può essere rimosso: è sufficiente riapplicame una goccia sullo strato già asciugato e asportare immediatamente con una garza in cotone. In particolare, si evidenzia l’associazione della nitrocellulosa, del castor oil e del tocoferolo. La nitrocellulosa riesce a formare un film sigillante, resistente all’acqua ed al tatto, che asciuga in brevissimo tempo, non dannoso per repidermide, che chiude la ragade sigillandola ed impedendo la sensazione di dolore conseguente al contatto con l’acqua, l’aria e le sostanze chimiche. L’associazione con castor oil permette di donare allo strato così formato e resistente una elasticità adeguata alle pieghe cutanee ed alla motilità tipica degli arti. L’associazione con Tocoferolo favorisce la cicatrizzazione dell’epidermide al di sotto dello strato sigillante. The composition comes in the form of a gel and is indicated in the treatment of small fissures, cracks, fissures, splits of the feet and hands and small cuts that do not bleed. Under the film that forms the protective layer, Γ hydration of the skin is maintained which, therefore, heals “in a humid environment”. The healing process is favored both by maintaining the humid environment and by the vitamin E contained in the product applied to the fissure. The protective film protects the fissure from the aggression of external agents (such as bacteria, water, thermal and physical agents), prevents the crack from reopening, relieves pain and promotes healing. The product is applied, possibly with the help of a spatula, until the fissure is filled and covered and dries in a few seconds. The application can be renewed 2/3 times a day until complete healing. Normally the film is removed by itself after some time, with normal hand washing or rubbing. If necessary, the film can be removed: just reapply a drop on the already dried layer and remove immediately with a cotton gauze. In particular, the association of nitrocellulose, castor oil and tocopherol is highlighted. Nitrocellulose is able to form a sealing film, resistant to water and to the touch, which dries in a very short time, not harmful to skin, which closes the fissure, sealing it and preventing the sensation of pain resulting from contact with water, air and chemicals. The association with castor oil allows to give the so formed and resistant layer an elasticity suitable for skin folds and the typical motility of the limbs. The association with tocopherol promotes the healing of the epidermis below the sealing layer.
Claims (4)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000160A ITFI20100160A1 (en) | 2010-07-27 | 2010-07-27 | COMPOSITION FOR THE TREATMENT OF RAGADI. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000160A ITFI20100160A1 (en) | 2010-07-27 | 2010-07-27 | COMPOSITION FOR THE TREATMENT OF RAGADI. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITFI20100160A1 true ITFI20100160A1 (en) | 2012-01-28 |
Family
ID=43500066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT000160A ITFI20100160A1 (en) | 2010-07-27 | 2010-07-27 | COMPOSITION FOR THE TREATMENT OF RAGADI. |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | ITFI20100160A1 (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0258481A1 (en) * | 1986-09-04 | 1988-03-09 | Nisshin Flour Milling Co., Ltd. | Pharmaceutical compositions for the treatment of skin diseases |
| WO1997045098A2 (en) * | 1996-05-31 | 1997-12-04 | Giorgio Panin | Esters of vitamin e as products for topical application |
| CN1203083A (en) * | 1997-06-23 | 1998-12-30 | 南通三龙化妆品公司 | Antifissuration skin care cream for feet |
| WO2001037782A2 (en) * | 1999-11-17 | 2001-05-31 | The Sg Licensing Corporation | Method and composition for the treatment of scars |
| US20030039625A1 (en) * | 2001-08-21 | 2003-02-27 | Malmgren Janice K. | Conditioner that provides skin like an angel |
-
2010
- 2010-07-27 IT IT000160A patent/ITFI20100160A1/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0258481A1 (en) * | 1986-09-04 | 1988-03-09 | Nisshin Flour Milling Co., Ltd. | Pharmaceutical compositions for the treatment of skin diseases |
| WO1997045098A2 (en) * | 1996-05-31 | 1997-12-04 | Giorgio Panin | Esters of vitamin e as products for topical application |
| CN1203083A (en) * | 1997-06-23 | 1998-12-30 | 南通三龙化妆品公司 | Antifissuration skin care cream for feet |
| WO2001037782A2 (en) * | 1999-11-17 | 2001-05-31 | The Sg Licensing Corporation | Method and composition for the treatment of scars |
| US20030039625A1 (en) * | 2001-08-21 | 2003-02-27 | Malmgren Janice K. | Conditioner that provides skin like an angel |
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