IT8621892A1 - Process for the synthesis of tauroursodeoxycholic acid dihydrate - Google Patents

Process for the synthesis of tauroursodeoxycholic acid dihydrate

Info

Publication number
IT8621892A1
IT8621892A1 IT1986A21892A IT2189286A IT8621892A1 IT 8621892 A1 IT8621892 A1 IT 8621892A1 IT 1986A21892 A IT1986A21892 A IT 1986A21892A IT 2189286 A IT2189286 A IT 2189286A IT 8621892 A1 IT8621892 A1 IT 8621892A1
Authority
IT
Italy
Prior art keywords
synthesis
acid dihydrate
tauroursodeoxycholic acid
tauroursodeoxycholic
dihydrate
Prior art date
Application number
IT1986A21892A
Other languages
Italian (it)
Other versions
IT8621892A0 (en
IT1197330B (en
Original Assignee
Prod Chimici E Alimentari S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prod Chimici E Alimentari S P A filed Critical Prod Chimici E Alimentari S P A
Priority to IT21892/86A priority Critical patent/IT1197330B/en
Publication of IT8621892A0 publication Critical patent/IT8621892A0/en
Priority to JP62248219A priority patent/JPS63146895A/en
Priority to DE19873736918 priority patent/DE3736918A1/en
Publication of IT8621892A1 publication Critical patent/IT8621892A1/en
Application granted granted Critical
Publication of IT1197330B publication Critical patent/IT1197330B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C07J41/0061—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
IT21892/86A 1986-10-03 1986-10-03 PROCEDURE FOR THE SYNTHESIS OF TAUROURSODESOXICOLIC BIIDRATE ACID IT1197330B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT21892/86A IT1197330B (en) 1986-10-03 1986-10-03 PROCEDURE FOR THE SYNTHESIS OF TAUROURSODESOXICOLIC BIIDRATE ACID
JP62248219A JPS63146895A (en) 1986-10-03 1987-10-02 Synthesis of tauroylsodeoxycol acid
DE19873736918 DE3736918A1 (en) 1986-10-03 1987-10-30 Process for the preparation of tauroursodeoxycholic acid dihydrate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21892/86A IT1197330B (en) 1986-10-03 1986-10-03 PROCEDURE FOR THE SYNTHESIS OF TAUROURSODESOXICOLIC BIIDRATE ACID

Publications (3)

Publication Number Publication Date
IT8621892A0 IT8621892A0 (en) 1986-10-03
IT8621892A1 true IT8621892A1 (en) 1988-04-03
IT1197330B IT1197330B (en) 1988-11-30

Family

ID=11188314

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21892/86A IT1197330B (en) 1986-10-03 1986-10-03 PROCEDURE FOR THE SYNTHESIS OF TAUROURSODESOXICOLIC BIIDRATE ACID

Country Status (3)

Country Link
JP (1) JPS63146895A (en)
DE (1) DE3736918A1 (en)
IT (1) IT1197330B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260462A (en) * 1989-05-30 1993-11-09 Prodotti Chimici E Alimentari S.P.A. Purification of tauroursodesoxycholic acid dihydrate
JPH0749437B2 (en) * 1989-06-23 1995-05-31 東京田辺製薬株式会社 Method for producing sodium tauroursodeoxycholate
JPH0749438B2 (en) * 1990-10-31 1995-05-31 東京田辺製薬株式会社 Method for purifying taurine-conjugated bile acid
IT1270853B (en) * 1993-05-20 1997-05-13 Sanofi Elf PROCEDURE FOR THE PREPARATION OF TAUROCOLANIC DERIVATIVES
IT1283182B1 (en) * 1996-03-04 1998-04-16 Prodotti Chimici Alimentari CONJUGATED COMPOUNDS OF BILE ACIDS WITH THIO-TAURINE AND ITS N-ALKYL DERIVATIVES
EP1985622A1 (en) * 2007-04-23 2008-10-29 Prodotti Chimici E Alimentari Spa Process for the preparation of tauroursodesoxycholic acid
WO2010005594A1 (en) * 2008-07-10 2010-01-14 Regenemed Inc. Compositions and methods of producing ursodeoxycholic acid
CN105294809A (en) * 2015-12-21 2016-02-03 杭州和泽医药科技有限公司 Method for preparing tauro ursodesoxy cholic acid
CN105330715B (en) * 2016-01-04 2018-07-06 杭州和泽医药科技有限公司 A kind of preparation method of Tauro ursodesoxy cholic acid
IT201900005906A1 (en) 2019-04-16 2020-10-16 Dipharma Francis Srl PROCEDURE FOR THE PREPARATION OF CONJUGATES OF A CHOLANIC ACID

Also Published As

Publication number Publication date
JPS63146895A (en) 1988-06-18
DE3736918A1 (en) 1989-05-11
IT8621892A0 (en) 1986-10-03
IT1197330B (en) 1988-11-30

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Legal Events

Date Code Title Description
ITCP Complementary protection certificate

Free format text: CCP 291

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 291, 19920513; PRODOTTI CHIMICI E ALIMENTARI SPA

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971030