IT8449177A1 - Composti 5 - eteroarilimidazol - 2 -onici dotati di attivita' cardiotonica - Google Patents
Composti 5 - eteroarilimidazol - 2 -onici dotati di attivita' cardiotonicaInfo
- Publication number
- IT8449177A1 IT8449177A1 IT1984A49177A IT4917784A IT8449177A1 IT 8449177 A1 IT8449177 A1 IT 8449177A1 IT 1984A49177 A IT1984A49177 A IT 1984A49177A IT 4917784 A IT4917784 A IT 4917784A IT 8449177 A1 IT8449177 A1 IT 8449177A1
- Authority
- IT
- Italy
- Prior art keywords
- eteroarylimidazol
- onics
- compounds
- cardiotonic activity
- cardiotonic
- Prior art date
Links
- 230000003177 cardiotonic effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Treating Waste Gases (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/554,498 US4532250A (en) | 1983-11-23 | 1983-11-23 | 5-Heteroarylimidazol-2-ones having cardiotonic activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT8449177A0 IT8449177A0 (it) | 1984-11-16 |
| IT8449177A1 true IT8449177A1 (it) | 1986-05-16 |
| IT1178243B IT1178243B (it) | 1987-09-09 |
Family
ID=24213587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT49177/84A IT1178243B (it) | 1983-11-23 | 1984-11-16 | Composti 5-eteroarilimidazol-2-onici dotati di attivita' cardiotonica |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4532250A (it) |
| EP (1) | EP0162102B1 (it) |
| JP (1) | JPS61500494A (it) |
| AU (1) | AU570529B2 (it) |
| CA (1) | CA1258072A (it) |
| DE (1) | DE3480475D1 (it) |
| IT (1) | IT1178243B (it) |
| WO (1) | WO1985002402A1 (it) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4649146A (en) * | 1983-01-31 | 1987-03-10 | Fujisawa Pharmaceutical Co., Ltd. | Thiazole derivatives and pharmaceutical composition comprising the same |
| GR851296B (it) * | 1984-05-29 | 1985-11-25 | Pfizer | |
| US4698353A (en) * | 1985-11-13 | 1987-10-06 | Merrell Dow Pharmaceuticals Inc. | Cardiotonic heterocyclic oxazolones |
| US4728661A (en) * | 1985-11-13 | 1988-03-01 | Merrell Dow Pharmaceuticals Inc. | Cardiotonic phenyl oxazolones |
| US4670450A (en) * | 1985-11-13 | 1987-06-02 | Merrell Dow Pharmaceuticals Inc. | Cardiotonic thiazolones |
| GB8529362D0 (en) * | 1985-11-28 | 1986-01-02 | Pfizer Ltd | Quinolone cardiac stimulants |
| US4999365A (en) * | 1987-03-20 | 1991-03-12 | Merrell Dow Pharmaceuticals Inc. | Method of reducing reperfusion injury with imidazol-2-thiones |
| US4803210A (en) * | 1987-05-29 | 1989-02-07 | Merrell Dow Pharmaceuticals Inc. | Cardiotonic tricyclic oxazolones |
| US4743607A (en) * | 1987-05-29 | 1988-05-10 | Merrell Dow Pharmaceuticals Inc. | Cardiotonic tricyclic imidazolones |
| GB8827820D0 (en) * | 1988-11-29 | 1988-12-29 | Janssen Pharmaceutica Nv | (1h-azol-1-ylmethyl)substituted quinoline derivatives |
| US5593991A (en) * | 1993-07-16 | 1997-01-14 | Adams; Jerry L. | Imidazole compounds, use and process of making |
| AR017200A1 (es) | 1997-12-23 | 2001-08-22 | Astrazeneca Ab | Compuestos inhibidores de la proteina cinasa c, sales farmaceuticamente aceptables de los mismos, formulaciones farmaceuitcas que los comprenden, usode las mismas y proceso para la sintesis de dichos compuestos |
| SE9800835D0 (sv) | 1998-03-13 | 1998-03-13 | Astra Ab | New Compounds |
| US6492406B1 (en) | 1999-05-21 | 2002-12-10 | Astrazeneca Ab | Pharmaceutically active compounds |
| US6346625B1 (en) | 1999-06-23 | 2002-02-12 | Astrazeneca Ab | Protein kinase inhibitors |
| HUP0401949A3 (en) * | 2001-10-22 | 2009-07-28 | Mitsubishi Tanabe Pharma Corp | 4-imidazolin-2-one derivatives |
| US7473695B2 (en) * | 2001-10-22 | 2009-01-06 | Mitsubishi Tanabe Pharma Corporation | 4-imidazolin-2-one compounds |
| AU2004201666C1 (en) * | 2001-10-22 | 2006-10-12 | Tanabe Seiyaku Co., Ltd. | 4-Imidazolin-2-one compounds |
| ATE504583T1 (de) * | 2003-04-21 | 2011-04-15 | Mitsubishi Tanabe Pharma Corp | 4-imidazolin-2-onverbindungen |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2585388A (en) * | 1948-11-17 | 1952-02-12 | Lilly Co Eli | Preparation of 2-mercaptoimidazoles |
| US3303199A (en) * | 1963-07-15 | 1967-02-07 | Geigy Chem Corp | Certain imidazolone derivatives and process for making same |
| IL26729A (en) * | 1965-10-21 | 1970-10-30 | Geigy Ag J R | 2-mercaptoimidazole derivatives and process for their preparation |
| US3641049A (en) * | 1968-10-29 | 1972-02-08 | Jan Olof Sandstrom | Imidazoline-2-thiones |
| US3538104A (en) * | 1969-02-28 | 1970-11-03 | Geigy Chem Corp | Pyridyl-2-imidazolones |
| JPS5343958B2 (it) * | 1972-07-29 | 1978-11-24 | ||
| US4053480A (en) * | 1976-04-26 | 1977-10-11 | Velsicol Chemical Corporation | 1-thiadiazolyl-5-phenoxy- and phenylthioalkanoyloxy imidazolidinones |
| US4405635A (en) * | 1979-06-18 | 1983-09-20 | Merrell Dow Pharmaceuticals Inc. | 4-Aroylimidazol-2-ones and their use as pharmaceuticals |
| US4636516A (en) * | 1981-02-19 | 1987-01-13 | Yamanouchi Pharmaceutical Co., Ltd. | 3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds |
| US4405628A (en) * | 1981-03-05 | 1983-09-20 | Merrell Dow Pharmaceuticals Inc. | 4-Pyridylimidazolones and method of use |
| ZA827975B (en) * | 1981-11-04 | 1983-08-31 | Merrell Dow Pharma | Nover imidazolecarboxamide derivatives |
| PH19153A (en) * | 1981-11-04 | 1986-01-15 | Merrell Dow Pharma | Treatment of cardiac failure using imidazolecarboxylic acid derivatives |
-
1983
- 1983-11-23 US US06/554,498 patent/US4532250A/en not_active Expired - Fee Related
-
1984
- 1984-10-26 CA CA000466458A patent/CA1258072A/en not_active Expired
- 1984-11-13 DE DE8585900282T patent/DE3480475D1/de not_active Expired
- 1984-11-13 WO PCT/US1984/001854 patent/WO1985002402A1/en active IP Right Grant
- 1984-11-13 AU AU36783/84A patent/AU570529B2/en not_active Ceased
- 1984-11-13 JP JP59504367A patent/JPS61500494A/ja active Granted
- 1984-11-13 EP EP85900282A patent/EP0162102B1/en not_active Expired
- 1984-11-16 IT IT49177/84A patent/IT1178243B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0162102B1 (en) | 1989-11-15 |
| CA1258072A (en) | 1989-08-01 |
| EP0162102A4 (en) | 1986-03-18 |
| JPH0572390B2 (it) | 1993-10-12 |
| EP0162102A1 (en) | 1985-11-27 |
| DE3480475D1 (de) | 1989-12-21 |
| WO1985002402A1 (en) | 1985-06-06 |
| JPS61500494A (ja) | 1986-03-20 |
| IT8449177A0 (it) | 1984-11-16 |
| US4532250A (en) | 1985-07-30 |
| AU570529B2 (en) | 1988-03-17 |
| IT1178243B (it) | 1987-09-09 |
| AU3678384A (en) | 1985-06-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3472881D1 (de) | N-phenylsulfonyl-n'-pyrimidinyl- and -triazinyl urea | |
| DE3466986D1 (de) | N-phenylsulfonyl-n'-pyrimidinyl- and -triazinylurea | |
| IT8449177A0 (it) | Composti 5-eteroarilimidazol-2-onici dotati di attivita' cardiotonica | |
| IT1170237B (it) | Composti eteroaril-sostituiti con attivita' fungicida | |
| DE3472105D1 (de) | 4-heterocyclyl-vinyl-4'-styryl-biphenyls | |
| DK407684D0 (da) | Overfladeaktive midler | |
| FR2554228B1 (fr) | Detecteur d'approche | |
| IT1161228B (it) | Benzoil-uree ad attivita' insetticida | |
| DK153567C (da) | Stabelbar petriskaal | |
| IT1183061B (it) | Composti dotati di attivita'antiallergica | |
| DK381884D0 (da) | 4'-halogenanthracyclinglycosider | |
| IT8421933A0 (it) | Sostanze ad attivita'ipolipemizzante. | |
| IT1161927B (it) | Furano-derivati ad attivita' fungicida | |
| IT8324438A0 (it) | Triazolil-cheto-derivati aventi attivita' fungicida. | |
| IT1163092B (it) | Nuovi composti ad attivita' mucoregolatrice | |
| IT1161212B (it) | Composizione ad attivita' atabagica | |
| IT1169958B (it) | Composti insetticidi ad attivita' ormonica giovanile | |
| IT1170276B (it) | Composti ad attivita' antiinfiammatoria | |
| IT8324396A0 (it) | Composto ad attivita' nootropa | |
| ES272849Y (es) | "embalaje-presentador mejorado" | |
| SE8305955D0 (sv) | All-round-mix "lifestream" | |
| IT8304732V0 (it) | Giracitta' | |
| ES272893Y (es) | "muneco desmontable" | |
| IT8223267A0 (it) | Composti ad attivita' vasodilatrice | |
| IT8323518A0 (it) | Composto ad attivita'antiarteriosclerotica. |