IT201700045255A1 - Metodo per modulare l'assorbimento fagocitario di un principio attivo o un suo precursore da parte di macrofagi. - Google Patents

Metodo per modulare l'assorbimento fagocitario di un principio attivo o un suo precursore da parte di macrofagi.

Info

Publication number
IT201700045255A1
IT201700045255A1 IT102017000045255A IT201700045255A IT201700045255A1 IT 201700045255 A1 IT201700045255 A1 IT 201700045255A1 IT 102017000045255 A IT102017000045255 A IT 102017000045255A IT 201700045255 A IT201700045255 A IT 201700045255A IT 201700045255 A1 IT201700045255 A1 IT 201700045255A1
Authority
IT
Italy
Prior art keywords
fagocytic
macrophages
modulate
precursor
absorption
Prior art date
Application number
IT102017000045255A
Other languages
English (en)
Inventor
Alessandro Dalpiaz
Barbara Pavan
Marco Fogagnolo
Guglielmo Paganetto
Eliana Grazia Leo
Valentina Iannuccelli
Eleonora Maretti
Original Assignee
Univ Degli Studi Di Ferrara
Univ Degli Studi Di Modena E Reggio Emilia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Di Ferrara, Univ Degli Studi Di Modena E Reggio Emilia filed Critical Univ Degli Studi Di Ferrara
Priority to IT102017000045255A priority Critical patent/IT201700045255A1/it
Priority to PCT/IB2018/052849 priority patent/WO2018198030A1/en
Publication of IT201700045255A1 publication Critical patent/IT201700045255A1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/554—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being a steroid plant sterol, glycyrrhetic acid, enoxolone or bile acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT102017000045255A 2017-04-26 2017-04-26 Metodo per modulare l'assorbimento fagocitario di un principio attivo o un suo precursore da parte di macrofagi. IT201700045255A1 (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT102017000045255A IT201700045255A1 (it) 2017-04-26 2017-04-26 Metodo per modulare l'assorbimento fagocitario di un principio attivo o un suo precursore da parte di macrofagi.
PCT/IB2018/052849 WO2018198030A1 (en) 2017-04-26 2018-04-24 Method for modulating phagocytic uptake of an active ingredient or a precursor thereof by macrophages

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102017000045255A IT201700045255A1 (it) 2017-04-26 2017-04-26 Metodo per modulare l'assorbimento fagocitario di un principio attivo o un suo precursore da parte di macrofagi.

Publications (1)

Publication Number Publication Date
IT201700045255A1 true IT201700045255A1 (it) 2018-10-26

Family

ID=59811843

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102017000045255A IT201700045255A1 (it) 2017-04-26 2017-04-26 Metodo per modulare l'assorbimento fagocitario di un principio attivo o un suo precursore da parte di macrofagi.

Country Status (2)

Country Link
IT (1) IT201700045255A1 (it)
WO (1) WO2018198030A1 (it)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100209353A1 (en) * 2009-02-19 2010-08-19 Korea Institute Of Science And Technology Tumor targeting protein conjugate and a method for preparing the same
KR20150001693A (ko) * 2014-08-25 2015-01-06 한국교통대학교산학협력단 헤파린-도세탁셀-토로콜산 접합체로 이루어진 표적성이 향상된 수용성 항암제 및 그의 제조방법

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100209353A1 (en) * 2009-02-19 2010-08-19 Korea Institute Of Science And Technology Tumor targeting protein conjugate and a method for preparing the same
KR20150001693A (ko) * 2014-08-25 2015-01-06 한국교통대학교산학협력단 헤파린-도세탁셀-토로콜산 접합체로 이루어진 표적성이 향상된 수용성 항암제 및 그의 제조방법

Also Published As

Publication number Publication date
WO2018198030A1 (en) 2018-11-01

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