IT1405498B1 - SUPRAMOLECULAR COMPLEXES OF SPERMIDINE FOR REGENERATION AND TISSUE TROPHISM. - Google Patents

SUPRAMOLECULAR COMPLEXES OF SPERMIDINE FOR REGENERATION AND TISSUE TROPHISM.

Info

Publication number
IT1405498B1
IT1405498B1 ITMI2010A001491A ITMI20101491A IT1405498B1 IT 1405498 B1 IT1405498 B1 IT 1405498B1 IT MI2010A001491 A ITMI2010A001491 A IT MI2010A001491A IT MI20101491 A ITMI20101491 A IT MI20101491A IT 1405498 B1 IT1405498 B1 IT 1405498B1
Authority
IT
Italy
Prior art keywords
spermidine
regeneration
supramolecular complexes
tissue trophism
trophism
Prior art date
Application number
ITMI2010A001491A
Other languages
Italian (it)
Inventor
Carlo Ghisalberti
Original Assignee
Ghisalberti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ITMI2010A001491A priority Critical patent/IT1405498B1/en
Application filed by Ghisalberti filed Critical Ghisalberti
Priority to CN201180047745.8A priority patent/CN103153293B/en
Priority to PCT/IB2011/001789 priority patent/WO2012017290A1/en
Priority to PCT/IB2011/001771 priority patent/WO2012017288A2/en
Priority to EP20110814164 priority patent/EP2600858A4/en
Priority to DK15153105.0T priority patent/DK2898881T3/en
Priority to EP15153102.7A priority patent/EP2902019B1/en
Priority to CA2807266A priority patent/CA2807266C/en
Priority to EP11814166.2A priority patent/EP2608781A4/en
Priority to ES15153105T priority patent/ES2704694T3/en
Priority to EP15153105.0A priority patent/EP2898881B1/en
Priority to PL15153105T priority patent/PL2898881T3/en
Priority to US13/813,939 priority patent/US20130310462A1/en
Priority to CN201610149456.3A priority patent/CN105797159B/en
Priority to RS20181578A priority patent/RS58287B1/en
Publication of ITMI20101491A1 publication Critical patent/ITMI20101491A1/en
Application granted granted Critical
Publication of IT1405498B1 publication Critical patent/IT1405498B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
ITMI2010A001491A 2010-08-04 2010-08-04 SUPRAMOLECULAR COMPLEXES OF SPERMIDINE FOR REGENERATION AND TISSUE TROPHISM. IT1405498B1 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
ITMI2010A001491A IT1405498B1 (en) 2010-08-04 2010-08-04 SUPRAMOLECULAR COMPLEXES OF SPERMIDINE FOR REGENERATION AND TISSUE TROPHISM.
EP15153105.0A EP2898881B1 (en) 2010-08-04 2011-08-01 Compositions comprising supramolecular complexes of polyanionic polymers and spermidine for use in the treatment of periodontum and damaged oral tissue
PCT/IB2011/001771 WO2012017288A2 (en) 2010-08-04 2011-08-01 Supramolecular complexes of polyanionic polymers and spermidine in tissue maintenance and repair
EP20110814164 EP2600858A4 (en) 2010-08-04 2011-08-01 Supramolecular complexes of polyanionic polymers and spermidine in tissue maintenance and repair
DK15153105.0T DK2898881T3 (en) 2010-08-04 2011-08-01 COMPOSITIONS COMPREHENSIVE SUPRAMOLECULAR COMPLEXES OF POLYANIONIC POLYMERS AND SPERMIDINE FOR USE IN TREATMENT OF THE PERIODONTY AND DAMAGED ORAL TISSUE.
EP15153102.7A EP2902019B1 (en) 2010-08-04 2011-08-01 Compositions comprising inclusion complexes of cyclodextrins with spermidine for use in oral care
CN201180047745.8A CN103153293B (en) 2010-08-04 2011-08-01 For organizational protection and the multi-anion copolymer of reparation and the supramolecular complex of spermidine
EP11814166.2A EP2608781A4 (en) 2010-08-04 2011-08-01 Inclusion complexes of cyclodextrins with spermidine, and proliferative/reparative compositions comprising thereof
ES15153105T ES2704694T3 (en) 2010-08-04 2011-08-01 Compositions comprising supramolecular complexes of polyanionic polymers and spermidine for use in the treatment of periodontium and damaged oral tissue
PCT/IB2011/001789 WO2012017290A1 (en) 2010-08-04 2011-08-01 Inclusion complexes of cyclodextrins with spermidine, and proliferative/reparative compositions comprising thereof
PL15153105T PL2898881T3 (en) 2010-08-04 2011-08-01 Compositions comprising supramolecular complexes of polyanionic polymers and spermidine for use in the treatment of periodontum and damaged oral tissue
US13/813,939 US20130310462A1 (en) 2010-08-04 2011-08-01 Supramolecular complexes of polyanionic polymers and spermidine in tissue maintenance and repair
CN201610149456.3A CN105797159B (en) 2010-08-04 2011-08-01 Use of a composition comprising supramolecular complexes of polyanionic polymers and spermidine for periodontal and damaged oral tissue
RS20181578A RS58287B1 (en) 2010-08-04 2011-08-01 Compositions comprising supramolecular complexes of polyanionic polymers and spermidine for use in the treatment of periodontum and damaged oral tissue
CA2807266A CA2807266C (en) 2010-08-04 2011-08-01 Supramolecular complexes of polyanionic polymers and spermidine in tissue maintenance and repair

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI2010A001491A IT1405498B1 (en) 2010-08-04 2010-08-04 SUPRAMOLECULAR COMPLEXES OF SPERMIDINE FOR REGENERATION AND TISSUE TROPHISM.

Publications (2)

Publication Number Publication Date
ITMI20101491A1 ITMI20101491A1 (en) 2012-02-05
IT1405498B1 true IT1405498B1 (en) 2014-01-17

Family

ID=43508745

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI2010A001491A IT1405498B1 (en) 2010-08-04 2010-08-04 SUPRAMOLECULAR COMPLEXES OF SPERMIDINE FOR REGENERATION AND TISSUE TROPHISM.

Country Status (1)

Country Link
IT (1) IT1405498B1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507321A (en) * 1982-02-17 1985-03-26 The Research Foundation Of State University Of New York Epithelial cell growth regulating composition containing polyamines and a method of using same
WO2010017328A2 (en) * 2008-08-06 2010-02-11 Rgo Biosciences Llc Cyclodextrin conjugates
JP2012506900A (en) * 2008-10-28 2012-03-22 ウニベルシダーデ デ サンティアゴ デ コンポステラ Nanoparticle systems prepared from anionic polymers

Also Published As

Publication number Publication date
ITMI20101491A1 (en) 2012-02-05

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