IT1400961B1 - ALISKIREN PRODUCTION PROCESS - Google Patents

ALISKIREN PRODUCTION PROCESS

Info

Publication number
IT1400961B1
IT1400961B1 ITMI2010A001008A ITMI20101008A IT1400961B1 IT 1400961 B1 IT1400961 B1 IT 1400961B1 IT MI2010A001008 A ITMI2010A001008 A IT MI2010A001008A IT MI20101008 A ITMI20101008 A IT MI20101008A IT 1400961 B1 IT1400961 B1 IT 1400961B1
Authority
IT
Italy
Prior art keywords
aliskiren
production process
production
aliskiren production
Prior art date
Application number
ITMI2010A001008A
Other languages
Italian (it)
Inventor
Luca Carcone
Maurizio Taddei
Elena Cini
Luca Banfi
Adele Russo
Marcello Rasparini
Renata Riva
Romina Vitale
Original Assignee
Chemo Iberica Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Iberica Sa filed Critical Chemo Iberica Sa
Priority to ITMI2010A001008A priority Critical patent/IT1400961B1/en
Priority to TW100118590A priority patent/TW201202178A/en
Priority to UY0001033425A priority patent/UY33425A/en
Priority to EP11728793.8A priority patent/EP2576500A2/en
Priority to ARP110101938A priority patent/AR081836A1/en
Priority to CA2801126A priority patent/CA2801126A1/en
Priority to PCT/EP2011/059196 priority patent/WO2011151442A2/en
Priority to US13/701,440 priority patent/US9346745B2/en
Publication of ITMI20101008A1 publication Critical patent/ITMI20101008A1/en
Application granted granted Critical
Publication of IT1400961B1 publication Critical patent/IT1400961B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ITMI2010A001008A 2010-06-04 2010-06-04 ALISKIREN PRODUCTION PROCESS IT1400961B1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ITMI2010A001008A IT1400961B1 (en) 2010-06-04 2010-06-04 ALISKIREN PRODUCTION PROCESS
TW100118590A TW201202178A (en) 2010-06-04 2011-05-27 Process for producing Aliskiren
UY0001033425A UY33425A (en) 2010-06-04 2011-06-02 PROCESS FOR THE PRODUCTION OF ALISKIREN
EP11728793.8A EP2576500A2 (en) 2010-06-04 2011-06-03 Process for producing aliskiren
ARP110101938A AR081836A1 (en) 2010-06-04 2011-06-03 PROCESS FOR THE PRODUCTION OF ALISKIREN, PROCEDURE FOR THE PREPARATION OF INTERMEDIARIES FOR THEIR SYNTHESIS AND COMPOUNDS NEEDED TO OBTAIN THESE LAST
CA2801126A CA2801126A1 (en) 2010-06-04 2011-06-03 Process for producing aliskiren
PCT/EP2011/059196 WO2011151442A2 (en) 2010-06-04 2011-06-03 Process for producing aliskiren
US13/701,440 US9346745B2 (en) 2010-06-04 2011-06-03 Process for producing Aliskiren

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI2010A001008A IT1400961B1 (en) 2010-06-04 2010-06-04 ALISKIREN PRODUCTION PROCESS

Publications (2)

Publication Number Publication Date
ITMI20101008A1 ITMI20101008A1 (en) 2011-12-05
IT1400961B1 true IT1400961B1 (en) 2013-07-05

Family

ID=43466513

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI2010A001008A IT1400961B1 (en) 2010-06-04 2010-06-04 ALISKIREN PRODUCTION PROCESS

Country Status (1)

Country Link
IT (1) IT1400961B1 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY119161A (en) * 1994-04-18 2005-04-30 Novartis Ag Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities
WO2006083924A1 (en) * 2005-02-02 2006-08-10 Vitae Pharmaceuticals, Inc. 1-acylamino-2-hydroxy-3-amino-w-arylalkanes as renin inhibitors
CN101346333A (en) * 2005-12-23 2009-01-14 巴斯夫欧洲公司 Method for producing an alpha-chiral chloromethyl compound in a pure form
WO2009007461A1 (en) * 2007-07-11 2009-01-15 Dsm Ip Assets B.V. Preparation of a saturated aldehyde
CN102164903B (en) * 2008-07-23 2015-01-14 帝斯曼知识产权资产管理有限公司 Synthesis routes to 2(S),4(S),5(S),7(S)-2,7-dialkyl-4-hydroxy-5-amino-8-aryl-octanoyl amides

Also Published As

Publication number Publication date
ITMI20101008A1 (en) 2011-12-05

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