IT1396810B1 - Dispositivo per la rilevazione di analiti in un campione biologico - Google Patents

Dispositivo per la rilevazione di analiti in un campione biologico

Info

Publication number
IT1396810B1
IT1396810B1 ITUD2009A000187A ITUD20090187A IT1396810B1 IT 1396810 B1 IT1396810 B1 IT 1396810B1 IT UD2009A000187 A ITUD2009A000187 A IT UD2009A000187A IT UD20090187 A ITUD20090187 A IT UD20090187A IT 1396810 B1 IT1396810 B1 IT 1396810B1
Authority
IT
Italy
Prior art keywords
analytes
detection
biological sample
biological
sample
Prior art date
Application number
ITUD2009A000187A
Other languages
English (en)
Inventor
Patrizia Melpignano
Original Assignee
Or El Organska Elektronika D O O
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Or El Organska Elektronika D O O filed Critical Or El Organska Elektronika D O O
Priority to ITUD2009A000187A priority Critical patent/IT1396810B1/it
Priority to US13/503,275 priority patent/US8647578B2/en
Priority to PCT/IB2010/002682 priority patent/WO2011048472A1/en
Priority to EP10785512.4A priority patent/EP2491371B1/en
Priority to BR112012009527A priority patent/BR112012009527A2/pt
Priority to CA2777180A priority patent/CA2777180A1/en
Publication of ITUD20090187A1 publication Critical patent/ITUD20090187A1/it
Application granted granted Critical
Publication of IT1396810B1 publication Critical patent/IT1396810B1/it
Priority to US14/153,666 priority patent/US20140128293A1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G01N21/6454—Individual samples arranged in a regular 2D-array, e.g. multiwell plates using an integrated detector array
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B01L2300/027—Digital display, e.g. LCD, LED
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0851—Bottom walls
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G01N2021/056—Laminated construction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G01N2201/0628—Organic LED [OLED]
ITUD2009A000187A 2009-10-21 2009-10-21 Dispositivo per la rilevazione di analiti in un campione biologico IT1396810B1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITUD2009A000187A IT1396810B1 (it) 2009-10-21 2009-10-21 Dispositivo per la rilevazione di analiti in un campione biologico
US13/503,275 US8647578B2 (en) 2009-10-21 2010-10-20 Device to detect analytes in a biological sample
PCT/IB2010/002682 WO2011048472A1 (en) 2009-10-21 2010-10-20 Device to detect analytes in a biological sample
EP10785512.4A EP2491371B1 (en) 2009-10-21 2010-10-20 Device and method to detect analytes in a biological sample, and process for producing the device
BR112012009527A BR112012009527A2 (pt) 2009-10-21 2010-10-20 dispositivo para detectar pelo menos um analito.
CA2777180A CA2777180A1 (en) 2009-10-21 2010-10-20 Device to detect analytes in a biological sample
US14/153,666 US20140128293A1 (en) 2009-10-21 2014-01-13 Device to detect analytes in a biological sample

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUD2009A000187A IT1396810B1 (it) 2009-10-21 2009-10-21 Dispositivo per la rilevazione di analiti in un campione biologico

Publications (2)

Publication Number Publication Date
ITUD20090187A1 ITUD20090187A1 (it) 2011-04-22
IT1396810B1 true IT1396810B1 (it) 2012-12-14

Family

ID=42225012

Family Applications (1)

Application Number Title Priority Date Filing Date
ITUD2009A000187A IT1396810B1 (it) 2009-10-21 2009-10-21 Dispositivo per la rilevazione di analiti in un campione biologico

Country Status (6)

Country Link
US (2) US8647578B2 (it)
EP (1) EP2491371B1 (it)
BR (1) BR112012009527A2 (it)
CA (1) CA2777180A1 (it)
IT (1) IT1396810B1 (it)
WO (1) WO2011048472A1 (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014085858A1 (en) * 2012-12-04 2014-06-12 The University Of Queensland Method for the detection of analytes via luminescence quenching
JP2015149389A (ja) * 2014-02-06 2015-08-20 ルネサスエレクトロニクス株式会社 半導体発光素子およびその製造方法
GB2570267A (en) * 2017-06-30 2019-07-24 Sumitomo Chemical Co Device and method
CN107655834B (zh) * 2017-09-19 2020-02-21 南京大学 一种基于表面等离激元共振单元的偏振传感器及传感方法
US11283238B2 (en) 2017-11-14 2022-03-22 The Penn State Research Foundation Charged polaron-polaritons in an organic semiconductor microcavity
DE102019117045B4 (de) 2019-06-25 2021-01-07 Sentronic GmbH - Gesellschaft für optische Meßsysteme Sensormodul zur multiparametrischen Analyse eines Mediums
CN111250181B (zh) * 2020-01-17 2021-11-30 上海新微技术研发中心有限公司 基于cmos图像传感的光波导多微流道芯片的制造方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7387891B2 (en) * 1999-05-17 2008-06-17 Applera Corporation Optical instrument including excitation source
US6677709B1 (en) * 2000-07-18 2004-01-13 General Electric Company Micro electromechanical system controlled organic led and pixel arrays and method of using and of manufacturing same
US6905816B2 (en) 2000-11-27 2005-06-14 Intelligent Medical Devices, Inc. Clinically intelligent diagnostic devices and methods
US20030035755A1 (en) 2001-08-16 2003-02-20 Shu-Hui Chen Organic electroluminescence (OEL)-based biochips
IL162632A0 (en) 2001-12-27 2005-11-20 Inverness Medical Switzerland Novel device, system and method forfluorescence detection
US8809071B2 (en) 2002-11-29 2014-08-19 Marcella Chiari Method for immobilizing biologic molecules on solid surfaces
WO2005103652A1 (en) 2004-04-21 2005-11-03 Ausbiochip Pty Ltd Optoelectronic biochip
US7091523B2 (en) * 2004-05-13 2006-08-15 Eastman Kodak Company Color OLED device having improved performance
US20080277606A1 (en) 2005-11-11 2008-11-13 Molecular Vision Limited Microfluidic Device
WO2007097572A1 (en) 2006-02-22 2007-08-30 Chungbuk National University Industry-Academic Cooperation Foundation Sensing structure of biochip and method thereof
TWI475737B (zh) * 2006-03-08 2015-03-01 Semiconductor Energy Lab 發光元件、發光裝置及電子裝置
WO2007107892A1 (en) 2006-03-21 2007-09-27 Koninklijke Philips Electronics N.V. Microelectronic sensor device with sensor array
KR101386216B1 (ko) * 2006-06-07 2014-04-18 삼성디스플레이 주식회사 유기 발광 소자
KR100942365B1 (ko) * 2007-02-05 2010-02-12 주식회사 엘지화학 발광효율이 우수한 유기발광소자 및 이의 제조방법

Also Published As

Publication number Publication date
WO2011048472A1 (en) 2011-04-28
BR112012009527A2 (pt) 2019-09-24
US20120213670A1 (en) 2012-08-23
US20140128293A1 (en) 2014-05-08
CA2777180A1 (en) 2011-04-28
EP2491371A1 (en) 2012-08-29
US8647578B2 (en) 2014-02-11
EP2491371B1 (en) 2020-03-11
ITUD20090187A1 (it) 2011-04-22

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