IT1314197B1 - 10-Formyltetrahydrofolate dehydrogenase, useful as a therapeutic agent, particularly as an antitumor agent possessing high cytotoxicity - Google Patents

10-Formyltetrahydrofolate dehydrogenase, useful as a therapeutic agent, particularly as an antitumor agent possessing high cytotoxicity

Info

Publication number
IT1314197B1
IT1314197B1 ITMI992197A IT1314197B1 IT 1314197 B1 IT1314197 B1 IT 1314197B1 IT MI992197 A ITMI992197 A IT MI992197A IT 1314197 B1 IT1314197 B1 IT 1314197B1
Authority
IT
Italy
Prior art keywords
useful
therapeutic agent
possessing high
high cytotoxicity
formyltetrahydrofolate dehydrogenase
Prior art date
Application number
Other languages
Italian (it)
Inventor
Alberto Bartorelli
Original Assignee
Pharmaproducts Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmaproducts Uk Ltd filed Critical Pharmaproducts Uk Ltd
Publication of ITMI992197A0 publication Critical patent/ITMI992197A0/en
Priority to IT1999MI002197 priority Critical patent/IT1314197B1/en
Priority to AT00945698T priority patent/ATE247976T1/en
Priority to ES00945698T priority patent/ES2204649T3/en
Priority to JP2001501245A priority patent/JP2003501398A/en
Priority to PCT/EP2000/005066 priority patent/WO2000074711A2/en
Priority to EP00945698A priority patent/EP1181046B1/en
Priority to AU59695/00A priority patent/AU5969500A/en
Priority to DE60004819T priority patent/DE60004819T2/en
Publication of ITMI992197A1 publication Critical patent/ITMI992197A1/en
Application granted granted Critical
Publication of IT1314197B1 publication Critical patent/IT1314197B1/en

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The use of 10-formyltetrahydrofolate dehydrogenase (I) as a therapeutic agent, is new. ACTIVITY : Cytostatic. MECHANISM OF ACTION : Cytotoxicity is mediated by cytotoxic antibodies to human tumor cells, particularly carcinomas and adenocarcinomas.
IT1999MI002197 1999-06-03 1999-10-20 10-Formyltetrahydrofolate dehydrogenase, useful as a therapeutic agent, particularly as an antitumor agent possessing high cytotoxicity IT1314197B1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT1999MI002197 IT1314197B1 (en) 1999-10-20 1999-10-20 10-Formyltetrahydrofolate dehydrogenase, useful as a therapeutic agent, particularly as an antitumor agent possessing high cytotoxicity
PCT/EP2000/005066 WO2000074711A2 (en) 1999-06-03 2000-06-02 10-formyltetrahydrofolate dehydrogenase as therapeutical agent
ES00945698T ES2204649T3 (en) 1999-06-03 2000-06-02 `10-FORMILTETRAHYDROPHOLATE DEHYDROGENASE AS A THERAPEUTIC AGENT.
JP2001501245A JP2003501398A (en) 1999-06-03 2000-06-02 10-formyltetrahydrofolate dehydrogenase as therapeutic agent
AT00945698T ATE247976T1 (en) 1999-06-03 2000-06-02 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE AS A THERAPEUTIC AGENT
EP00945698A EP1181046B1 (en) 1999-06-03 2000-06-02 10-formyltetrahydrofolate dehydrogenase as therapeutical agent
AU59695/00A AU5969500A (en) 1999-06-03 2000-06-02 10-formyltetrahydrofolate dehydrogenase as therapeutical agent
DE60004819T DE60004819T2 (en) 1999-06-03 2000-06-02 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE AS A THERAPEUTIC AGENT

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI002197 IT1314197B1 (en) 1999-10-20 1999-10-20 10-Formyltetrahydrofolate dehydrogenase, useful as a therapeutic agent, particularly as an antitumor agent possessing high cytotoxicity

Publications (3)

Publication Number Publication Date
ITMI992197A0 ITMI992197A0 (en) 1999-10-20
ITMI992197A1 ITMI992197A1 (en) 2001-04-20
IT1314197B1 true IT1314197B1 (en) 2002-12-06

Family

ID=11383818

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999MI002197 IT1314197B1 (en) 1999-06-03 1999-10-20 10-Formyltetrahydrofolate dehydrogenase, useful as a therapeutic agent, particularly as an antitumor agent possessing high cytotoxicity

Country Status (1)

Country Link
IT (1) IT1314197B1 (en)

Also Published As

Publication number Publication date
ITMI992197A0 (en) 1999-10-20
ITMI992197A1 (en) 2001-04-20

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