IT1278136B1 - ASSOCIATION ESTABLISHED DSA LACTOFERRIN (OR ITS ANALOGUES) AND DEFEROXAMINE METALSULFONATE (OR OTHER METALLIC ION CHELATORS) FOR - Google Patents
ASSOCIATION ESTABLISHED DSA LACTOFERRIN (OR ITS ANALOGUES) AND DEFEROXAMINE METALSULFONATE (OR OTHER METALLIC ION CHELATORS) FORInfo
- Publication number
- IT1278136B1 IT1278136B1 IT95RM000472A ITRM950472A IT1278136B1 IT 1278136 B1 IT1278136 B1 IT 1278136B1 IT 95RM000472 A IT95RM000472 A IT 95RM000472A IT RM950472 A ITRM950472 A IT RM950472A IT 1278136 B1 IT1278136 B1 IT 1278136B1
- Authority
- IT
- Italy
- Prior art keywords
- metalsulfonate
- deferoxamine
- lactoferrin
- dsa
- analogues
- Prior art date
Links
- 102000010445 Lactoferrin Human genes 0.000 title 1
- 108010063045 Lactoferrin Proteins 0.000 title 1
- UBQYURCVBFRUQT-UHFFFAOYSA-N N-benzoyl-Ferrioxamine B Chemical compound CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN UBQYURCVBFRUQT-UHFFFAOYSA-N 0.000 title 1
- 239000002738 chelating agent Substances 0.000 title 1
- 229960000958 deferoxamine Drugs 0.000 title 1
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 title 1
- 229940078795 lactoferrin Drugs 0.000 title 1
- 235000021242 lactoferrin Nutrition 0.000 title 1
- 150000001455 metallic ions Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95RM000472A IT1278136B1 (en) | 1995-07-12 | 1995-07-12 | ASSOCIATION ESTABLISHED DSA LACTOFERRIN (OR ITS ANALOGUES) AND DEFEROXAMINE METALSULFONATE (OR OTHER METALLIC ION CHELATORS) FOR |
| EP96830376A EP0753309A3 (en) | 1995-07-12 | 1996-07-03 | Preparation of lactoferrin (or analogous proteins) and desferrioxamine methanesulfonate (or other metal ion chelators) for the therapy of viral infectious diseases |
| CA002180683A CA2180683A1 (en) | 1995-07-12 | 1996-07-08 | Preparation of lactoferrin (or analogous proteins) and desferrioxamine methanesulfonate (or other metal ion chelators) for the therapy of viral infectious diseases |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95RM000472A IT1278136B1 (en) | 1995-07-12 | 1995-07-12 | ASSOCIATION ESTABLISHED DSA LACTOFERRIN (OR ITS ANALOGUES) AND DEFEROXAMINE METALSULFONATE (OR OTHER METALLIC ION CHELATORS) FOR |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITRM950472A0 ITRM950472A0 (en) | 1995-07-12 |
| ITRM950472A1 ITRM950472A1 (en) | 1997-01-12 |
| IT1278136B1 true IT1278136B1 (en) | 1997-11-17 |
Family
ID=11403471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT95RM000472A IT1278136B1 (en) | 1995-07-12 | 1995-07-12 | ASSOCIATION ESTABLISHED DSA LACTOFERRIN (OR ITS ANALOGUES) AND DEFEROXAMINE METALSULFONATE (OR OTHER METALLIC ION CHELATORS) FOR |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0753309A3 (en) |
| CA (1) | CA2180683A1 (en) |
| IT (1) | IT1278136B1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6172040B1 (en) * | 1999-05-28 | 2001-01-09 | A. Satyanarayan Naidu | Immobilized lactoferrin antimicrobial agents and the use thereof |
| WO2005085287A1 (en) | 2004-03-03 | 2005-09-15 | En-N-Tech, Inc. | Treatments for contaminant reduction in lactoferrin preparations and lactoferrin-containing compositions |
| EP3300742B1 (en) * | 2014-07-11 | 2020-11-04 | Grifols Worldwide Operations Limited | Transferrin for use in the treatment of hypoxia inducible factor (hif)-related conditions like ischemia |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5173505A (en) * | 1985-06-20 | 1992-12-22 | University Of Florida | Anti-neoplastic, anti-viral and ribonucleotide reductase activity affecting pharmaceutical compositions and methods of treatment |
| FR2626472B1 (en) * | 1988-02-02 | 1991-06-14 | Roussel Uclaf | USE OF MILK PROTEINS FOR THE MANUFACTURE OF AN ANTI-VIRAL DRUG |
| DE3842143A1 (en) * | 1988-12-15 | 1990-06-21 | Nitsche Dietrich | USE OF TRANSFERRIN FOR ENDOTOXIN NEUTRALIZATION |
| AU665381B2 (en) * | 1992-01-23 | 1996-01-04 | Morinaga Milk Industry Company Limited | Antibacterial agent and treatment of article therewith |
-
1995
- 1995-07-12 IT IT95RM000472A patent/IT1278136B1/en active IP Right Grant
-
1996
- 1996-07-03 EP EP96830376A patent/EP0753309A3/en not_active Withdrawn
- 1996-07-08 CA CA002180683A patent/CA2180683A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0753309A3 (en) | 1998-09-02 |
| CA2180683A1 (en) | 1997-01-13 |
| ITRM950472A1 (en) | 1997-01-12 |
| EP0753309A2 (en) | 1997-01-15 |
| ITRM950472A0 (en) | 1995-07-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |