IT1274482B - Biocatalytic process for obtaining optically pure enantiomers of Flurbiprofen - Google Patents

Biocatalytic process for obtaining optically pure enantiomers of Flurbiprofen

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Publication number
IT1274482B
IT1274482B ITMI950959A ITMI950959A IT1274482B IT 1274482 B IT1274482 B IT 1274482B IT MI950959 A ITMI950959 A IT MI950959A IT MI950959 A ITMI950959 A IT MI950959A IT 1274482 B IT1274482 B IT 1274482B
Authority
IT
Italy
Prior art keywords
flurbiprofen
optically pure
pure enantiomers
biocatalytic process
obtaining optically
Prior art date
Application number
ITMI950959A
Other languages
Italian (it)
Inventor
Giovanni Nicolosi
Mario Piatteli
Raffaele Morrone
Angela Patti
Original Assignee
Consiglio Nazionale Ricerche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale Ricerche filed Critical Consiglio Nazionale Ricerche
Priority to ITMI950959A priority Critical patent/IT1274482B/en
Publication of ITMI950959A0 publication Critical patent/ITMI950959A0/en
Publication of ITMI950959A1 publication Critical patent/ITMI950959A1/en
Application granted granted Critical
Publication of IT1274482B publication Critical patent/IT1274482B/en

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for the preparation of optically pure enantiomers of Flurbiprofen of formula I <IMAGE> which comprises esterification of the racemic acid with a lower aliphatic alcohol in the presence of supportive Candida antarctica lipases and separation of the acid ester is described.
ITMI950959A 1995-05-12 1995-05-12 Biocatalytic process for obtaining optically pure enantiomers of Flurbiprofen IT1274482B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ITMI950959A IT1274482B (en) 1995-05-12 1995-05-12 Biocatalytic process for obtaining optically pure enantiomers of Flurbiprofen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI950959A IT1274482B (en) 1995-05-12 1995-05-12 Biocatalytic process for obtaining optically pure enantiomers of Flurbiprofen

Publications (3)

Publication Number Publication Date
ITMI950959A0 ITMI950959A0 (en) 1995-05-12
ITMI950959A1 ITMI950959A1 (en) 1996-11-12
IT1274482B true IT1274482B (en) 1997-07-17

Family

ID=11371583

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI950959A IT1274482B (en) 1995-05-12 1995-05-12 Biocatalytic process for obtaining optically pure enantiomers of Flurbiprofen

Country Status (1)

Country Link
IT (1) IT1274482B (en)

Also Published As

Publication number Publication date
ITMI950959A0 (en) 1995-05-12
ITMI950959A1 (en) 1996-11-12

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