IT1273604B - New glutaryl-amino-substd. cephalosporanic acid derivs. - and related cephem and cepham carboxylic acid derivs., useful as intermediates for antibiotics - Google Patents
New glutaryl-amino-substd. cephalosporanic acid derivs. - and related cephem and cepham carboxylic acid derivs., useful as intermediates for antibioticsInfo
- Publication number
- IT1273604B IT1273604B ITMI950823A IT1273604B IT 1273604 B IT1273604 B IT 1273604B IT MI950823 A ITMI950823 A IT MI950823A IT 1273604 B IT1273604 B IT 1273604B
- Authority
- IT
- Italy
- Prior art keywords
- substd
- acid derivs
- glutaryl
- new
- cepham
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- YGBFLZPYDUKSPT-MRVPVSSYSA-N cephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)C[C@H]21 YGBFLZPYDUKSPT-MRVPVSSYSA-N 0.000 title 1
- -1 cepham carboxylic acid Chemical class 0.000 title 1
- 150000001782 cephems Chemical class 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- IXUSDMGLUJZNFO-BXUZGUMPSA-N (7R)-7-(4-carboxybutanamido)cephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCCC(O)=O)[C@@H]12 IXUSDMGLUJZNFO-BXUZGUMPSA-N 0.000 abstract 1
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Landscapes
- Cephalosporin Compounds (AREA)
Abstract
Glutaryl 7-aminocephalosporanic acid (7-ACA) derivs. of formula (I) are new. R = H, 1-4C alkyl (opt. substd. by phenyl or H (sic)), benzyl (substd. by NO2, 1-4C alkyl or 1-4C alkoxy) or silyl (substd. by (opt. substd.)1-4C alkyl); n = 0 or 1; A = H, OH, Cl, CH2 or CH2X; X = F, Cl, Br, I, OH, OCOMe or opt. substd. 1-4C alkoxy; provided that when n = O and R = H, then X is not OMe.
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT95MI000823 IT1273604B (en) | 1995-04-21 | 1995-04-21 | New glutaryl-amino-substd. cephalosporanic acid derivs. - and related cephem and cepham carboxylic acid derivs., useful as intermediates for antibiotics |
KR1019960701450A KR960704897A (en) | 1994-07-22 | 1995-07-17 | Glutaryl 7-ACA derivatives and processes for obtaining them |
EP95926916A EP0720611A1 (en) | 1994-07-22 | 1995-07-17 | Glutaryl 7-aca derivatives and processes for obtaining them |
CN95190659A CN1130908A (en) | 1994-07-22 | 1995-07-17 | Glutaryl 7-ACA derivatives and processes for obtaining them |
JP8501677A JPH09504306A (en) | 1994-07-22 | 1995-07-17 | Glitaryl 7-ACA derivative and process for its preparation |
PCT/EP1995/002802 WO1995035020A2 (en) | 1994-07-22 | 1995-07-17 | Glutaryl 7-aca derivatives and processes for obtaining them |
US08/605,135 US5750682A (en) | 1994-07-22 | 1995-07-17 | Glutaryl 7-ACA derivatives and processes for obtaining them |
TW084108408A TW401419B (en) | 1994-07-22 | 1995-08-10 | Glutaryl 7-ACA derivatives and processes for obtaining them |
US09/017,860 US6005101A (en) | 1994-07-22 | 1998-02-03 | Glutaryl 7-ACA derivatives and processes for obtaining them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT95MI000823 IT1273604B (en) | 1995-04-21 | 1995-04-21 | New glutaryl-amino-substd. cephalosporanic acid derivs. - and related cephem and cepham carboxylic acid derivs., useful as intermediates for antibiotics |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI950823A0 ITMI950823A0 (en) | 1995-04-21 |
ITMI950823A1 ITMI950823A1 (en) | 1996-10-21 |
IT1273604B true IT1273604B (en) | 1997-07-08 |
Family
ID=11371422
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT95MI000823 IT1273604B (en) | 1994-07-22 | 1995-04-21 | New glutaryl-amino-substd. cephalosporanic acid derivs. - and related cephem and cepham carboxylic acid derivs., useful as intermediates for antibiotics |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1273604B (en) |
-
1995
- 1995-04-21 IT IT95MI000823 patent/IT1273604B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ITMI950823A0 (en) | 1995-04-21 |
ITMI950823A1 (en) | 1996-10-21 |
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