IT1273311B - METHOD FOR ELECTROPHORETIC DATA PROCESSING - Google Patents

METHOD FOR ELECTROPHORETIC DATA PROCESSING

Info

Publication number
IT1273311B
IT1273311B ITMI940301A ITMI940301A IT1273311B IT 1273311 B IT1273311 B IT 1273311B IT MI940301 A ITMI940301 A IT MI940301A IT MI940301 A ITMI940301 A IT MI940301A IT 1273311 B IT1273311 B IT 1273311B
Authority
IT
Italy
Prior art keywords
data signals
densitograms
specific portions
electrophoregrams
data processing
Prior art date
Application number
ITMI940301A
Other languages
Italian (it)
Inventor
Hisamitsu Yokogawa
Original Assignee
Lympus Optical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP03068893A external-priority patent/JP3401040B2/en
Priority claimed from JP5060363A external-priority patent/JPH06273320A/en
Application filed by Lympus Optical Co Ltd filed Critical Lympus Optical Co Ltd
Publication of ITMI940301A0 publication Critical patent/ITMI940301A0/en
Publication of ITMI940301A1 publication Critical patent/ITMI940301A1/en
Application granted granted Critical
Publication of IT1273311B publication Critical patent/IT1273311B/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Water Treatment By Electricity Or Magnetism (AREA)

Abstract

Si applicano campioni insieme ad un campione standard su un substrato che viene sottoposto ad elettroforesi ottenendo elettroforegrammi. Gli elettroforegrammi vengono analizzati fotoelettricamente ricavando segnali di dati di campioni e segnali di dati di riferimento; i segnali di dati di campioni vengono normalizzati con riferimento ai segnali di dati di riferimento ed immagazzinati in memoria. Si reperiscono dalla memoria una pluralità di segnali di dati di campioni dello stesso paziente e si visualizzano in modo sovrapposto una pluralità di densitogrammi dello stesso paziente. Si rilevano porzioni specifiche dei densitogrammi quali proteine M e le porzioni specifiche rilevate vengono classificate per valutare tipi di porzioni specifiche che sono anche visualizzati. Il decorso della malattia può essere controllato in modo facile e preciso controllando densitogrammi visualizzati e tipi di porzioni specifiche.Samples are applied together with a standard sample on a substrate which is subjected to electrophoresis obtaining electrophoregrams. The electrophoregrams are analyzed photoelectrically by obtaining sample data signals and reference data signals; the sample data signals are normalized with reference to the reference data signals and stored in memory. A plurality of data signals from samples of the same patient are obtained from the memory and a plurality of densitograms from the same patient are superimposed. Specific portions of the densitograms such as M proteins are detected and the specific portions detected are classified to evaluate types of specific portions which are also displayed. The course of the disease can be controlled easily and precisely by checking displayed densitograms and specific portion types.

ITMI940301A 1993-02-19 1994-02-18 METHOD FOR ELECTROPHORETIC DATA PROCESSING IT1273311B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP03068893A JP3401040B2 (en) 1993-02-19 1993-02-19 How to display densitograms
JP5060363A JPH06273320A (en) 1993-03-19 1993-03-19 Automatic analyzing method and displaying method of electrophoretic image

Publications (3)

Publication Number Publication Date
ITMI940301A0 ITMI940301A0 (en) 1994-02-18
ITMI940301A1 ITMI940301A1 (en) 1995-08-18
IT1273311B true IT1273311B (en) 1997-07-08

Family

ID=26369085

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI940301A IT1273311B (en) 1993-02-19 1994-02-18 METHOD FOR ELECTROPHORETIC DATA PROCESSING

Country Status (2)

Country Link
DE (1) DE4405251C2 (en)
IT (1) IT1273311B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5567282A (en) * 1994-01-25 1996-10-22 Wang; Hann-Ping On-capillary electrophoretic immunosubtraction for classification and typing of M-proteins
US5853979A (en) 1995-06-30 1998-12-29 Visible Genetics Inc. Method and system for DNA sequence determination and mutation detection with reference to a standard
US5981186A (en) * 1995-06-30 1999-11-09 Visible Genetics, Inc. Method and apparatus for DNA-sequencing using reduced number of sequencing mixtures
WO1999034205A1 (en) 1997-12-30 1999-07-08 Caliper Technologies Corp. Software for the display of chromatographic separation data
US7222059B2 (en) 2001-11-15 2007-05-22 Siemens Medical Solutions Diagnostics Electrophoretic trace simulator

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4920498A (en) * 1985-08-17 1990-04-24 Olympus Optical Co., Ltd. Method of processing and analyzing electrophoretic image, and method of displaying electrophoregram and a medium for recording electrophoregram

Also Published As

Publication number Publication date
DE4405251A1 (en) 1994-08-25
DE4405251C2 (en) 1996-09-26
ITMI940301A0 (en) 1994-02-18
ITMI940301A1 (en) 1995-08-18

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