IT1272878B - Indole compounds - Google Patents

Indole compounds

Info

Publication number
IT1272878B
IT1272878B ITMI950030A ITMI950030A IT1272878B IT 1272878 B IT1272878 B IT 1272878B IT MI950030 A ITMI950030 A IT MI950030A IT MI950030 A ITMI950030 A IT MI950030A IT 1272878 B IT1272878 B IT 1272878B
Authority
IT
Italy
Prior art keywords
alkyl
phenyl
hydrogen
substituted
formula
Prior art date
Application number
ITMI950030A
Other languages
Italian (it)
Inventor
Carlo Farina
Stefania Gagliardi
Carlo Parini
Mario Pinza
Guy Marguerite Marie G Nadler
Marcel Jean-Marie Morvan
Original Assignee
Smithkline Beecham Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Spa filed Critical Smithkline Beecham Spa
Publication of ITMI950030A0 publication Critical patent/ITMI950030A0/en
Priority to ITMI950030A priority Critical patent/IT1272878B/en
Priority to PCT/EP1996/000157 priority patent/WO1996021644A1/en
Priority to PL96321263A priority patent/PL321263A1/en
Priority to CA002209936A priority patent/CA2209936A1/en
Priority to US08/860,760 priority patent/US5981525A/en
Priority to JP8521450A priority patent/JPH10512251A/en
Priority to TR97/00625T priority patent/TR199700625T1/en
Priority to HU9901096A priority patent/HUP9901096A3/en
Priority to AU45360/96A priority patent/AU4536096A/en
Priority to BR9606743A priority patent/BR9606743A/en
Priority to APAP/P/1997/001029A priority patent/AP648A/en
Priority to CZ972176A priority patent/CZ217697A3/en
Priority to SK932-97A priority patent/SK93297A3/en
Priority to EP96901275A priority patent/EP0802902A1/en
Priority to KR1019970704719A priority patent/KR19980701330A/en
Priority to ZA96121A priority patent/ZA96121B/en
Publication of ITMI950030A1 publication Critical patent/ITMI950030A1/en
Application granted granted Critical
Publication of IT1272878B publication Critical patent/IT1272878B/en
Priority to BG101769A priority patent/BG101769A/en
Priority to FI972919A priority patent/FI972919A/en
Priority to NO973178A priority patent/NO973178L/en
Priority to OA70046A priority patent/OA10611A/en
Priority to MXPA/A/1997/005243A priority patent/MXPA97005243A/en
Priority to EA199700098A priority patent/EA199700098A1/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

The compound of formula I: <IMAGE> or its salt or solvate in which: (i) Ra is hydrogen, alkyl or phenyl and Rb is a residue of formula (a): <IMAGE> in which X is hydroxy or alkoxy or X is the NRsRt group in which Rs and Rt are each separately hydrogen, alkyl, substituted alkyl, phenyl alkyl or heteroalkyl, R1 is alkyl or substituted or unsubstituted phenyl, and R2, R3 and R4 are each separately hydrogen, alkyl or phenyl, or (ii) Ra is a residue of formula (a) and Rb is hydrogen, alkyl or phenyl, R6 and R7 are each separately hydrogen, hydroxy, amino, alkoxy, substituted or unsubstituted phenoxy, substituted or unsubstituted benzyloxy, alkyl amino, dialkyl amino, chloro, alkyl, carboxy, carbalkoxy, carbamoyl, alkyl carbamoyl, or R6 and R7 are both methylene dioxy, carbonyl dioxy or carbonyl diamino, and R8 is hydrogen, alkanoyl or alkyl, are used for the treatment of osteoporosis.
ITMI950030A 1995-01-10 1995-01-10 Indole compounds IT1272878B (en)

Priority Applications (22)

Application Number Priority Date Filing Date Title
ITMI950030A IT1272878B (en) 1995-01-10 1995-01-10 Indole compounds
APAP/P/1997/001029A AP648A (en) 1995-01-10 1996-01-08 Indole derivatives useful in the treatment of osteoporosis.
SK932-97A SK93297A3 (en) 1995-01-10 1996-01-08 Indole derivatives, method for their producing, pharmaceutical comosition containing the same, and their use
CA002209936A CA2209936A1 (en) 1995-01-10 1996-01-08 Indole derivatives useful in the treatment of osteoporosis
US08/860,760 US5981525A (en) 1995-01-10 1996-01-08 Indole derivatives useful in the treatment of osteoporosis
JP8521450A JPH10512251A (en) 1995-01-10 1996-01-08 Indole derivatives useful for treating osteoporosis
TR97/00625T TR199700625T1 (en) 1995-01-10 1996-01-08 Indole derivatives useful in the treatment of osteoporosis (bone loss).
HU9901096A HUP9901096A3 (en) 1995-01-10 1996-01-08 Indole derivatives, preparation and use thereof, pharmaceutical composition containing these compounds
AU45360/96A AU4536096A (en) 1995-01-10 1996-01-08 Indole derivatives useful in the treatment of osteoporosis
BR9606743A BR9606743A (en) 1995-01-10 1996-01-08 Indole derivatives useful in the treatment of osteoporosis
PCT/EP1996/000157 WO1996021644A1 (en) 1995-01-10 1996-01-08 Indole derivatives useful in the treatment of osteoporosis
CZ972176A CZ217697A3 (en) 1995-01-10 1996-01-08 Indole derivatives, which can be used for treating osteoporosis, process of their preparation, pharmaceutical composition containing such derivatives and use
PL96321263A PL321263A1 (en) 1995-01-10 1996-01-08 Derivatives of indole useful in treating osteoporosis
EP96901275A EP0802902A1 (en) 1995-01-10 1996-01-08 Indole derivatives useful in the treatment of osteoporosis
KR1019970704719A KR19980701330A (en) 1995-01-10 1996-01-08 Indole Derivatives Useful in the Treatment of Osteoporosis (Indole Derivatives Useful in the Treatment of Osteoporosis)
ZA96121A ZA96121B (en) 1995-01-10 1996-01-09 Novel compounds
BG101769A BG101769A (en) 1995-01-10 1997-07-07 Indole derivatives useful in the treatment of osteoporosis
FI972919A FI972919A (en) 1995-01-10 1997-07-09 Indole derivatives useful in the treatment of osteoporosis
NO973178A NO973178L (en) 1995-01-10 1997-07-09 Indole derivatives useful in the treatment of osteoporosis
OA70046A OA10611A (en) 1995-01-10 1997-07-09 Indole derivatives useful in the treatment of osteoporosis
MXPA/A/1997/005243A MXPA97005243A (en) 1995-01-10 1997-07-10 Derivatives of indol and compositions of the same useful in the treatment of osteoporo
EA199700098A EA199700098A1 (en) 1995-01-10 1997-08-08 INDOL DERIVATIVES SUITABLE FOR THE TREATMENT OF OSTEOPOROSIS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI950030A IT1272878B (en) 1995-01-10 1995-01-10 Indole compounds

Publications (3)

Publication Number Publication Date
ITMI950030A0 ITMI950030A0 (en) 1995-01-10
ITMI950030A1 ITMI950030A1 (en) 1996-07-10
IT1272878B true IT1272878B (en) 1997-07-01

Family

ID=11370165

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI950030A IT1272878B (en) 1995-01-10 1995-01-10 Indole compounds

Country Status (2)

Country Link
IT (1) IT1272878B (en)
ZA (1) ZA96121B (en)

Also Published As

Publication number Publication date
ITMI950030A0 (en) 1995-01-10
ZA96121B (en) 1997-07-09
ITMI950030A1 (en) 1996-07-10

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Legal Events

Date Code Title Description
0001 Granted