IT1264084B1 - PEPTIDE WITH ACTIVITY AS A SUBSTRATE AND/OR INHIBITOR OF THE ENZYME TRANSGLUTAMINASE AND ITS USE IN DIAGNOSIS AND THERAPY. - Google Patents

PEPTIDE WITH ACTIVITY AS A SUBSTRATE AND/OR INHIBITOR OF THE ENZYME TRANSGLUTAMINASE AND ITS USE IN DIAGNOSIS AND THERAPY.

Info

Publication number
IT1264084B1
IT1264084B1 IT93RM000845A ITRM930845A IT1264084B1 IT 1264084 B1 IT1264084 B1 IT 1264084B1 IT 93RM000845 A IT93RM000845 A IT 93RM000845A IT RM930845 A ITRM930845 A IT RM930845A IT 1264084 B1 IT1264084 B1 IT 1264084B1
Authority
IT
Italy
Prior art keywords
peptide
diagnosis
therapy
substrate
inhibitor
Prior art date
Application number
IT93RM000845A
Other languages
Italian (it)
Inventor
Francesco Facchiano
Alberto Luini
Antonio Facchiano
Original Assignee
Raggio Italgene Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Raggio Italgene Spa filed Critical Raggio Italgene Spa
Priority to IT93RM000845A priority Critical patent/IT1264084B1/en
Publication of ITRM930845A0 publication Critical patent/ITRM930845A0/en
Priority to PCT/IT1994/000216 priority patent/WO1995017426A1/en
Priority to AU12798/95A priority patent/AU1279895A/en
Publication of ITRM930845A1 publication Critical patent/ITRM930845A1/en
Application granted granted Critical
Publication of IT1264084B1 publication Critical patent/IT1264084B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

E' descritto un peptide ad attività di substrato e/o di inibitore dell'enzima transglutaminasi, derivato dalla sinapsina Ia, da utilizzarsi in diagnosi e terapia di patologie correlate ad alterazioni della transglutaminasi.A peptide with substrate and / or inhibitor activity of the enzyme transglutaminase, derived from synapsin Ia, is described, to be used in the diagnosis and therapy of pathologies related to alterations of transglutaminase.

IT93RM000845A 1993-12-22 1993-12-22 PEPTIDE WITH ACTIVITY AS A SUBSTRATE AND/OR INHIBITOR OF THE ENZYME TRANSGLUTAMINASE AND ITS USE IN DIAGNOSIS AND THERAPY. IT1264084B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT93RM000845A IT1264084B1 (en) 1993-12-22 1993-12-22 PEPTIDE WITH ACTIVITY AS A SUBSTRATE AND/OR INHIBITOR OF THE ENZYME TRANSGLUTAMINASE AND ITS USE IN DIAGNOSIS AND THERAPY.
PCT/IT1994/000216 WO1995017426A1 (en) 1993-12-22 1994-12-22 Peptide effective as substrate and/or inhibitor of the transglutaminase enzyme and use thereof for diagnostics and therapeutics
AU12798/95A AU1279895A (en) 1993-12-22 1994-12-22 Peptide effective as substrate and/or inhibitor of the transglutaminase enzyme and use thereof for diagnostics and therapeutics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93RM000845A IT1264084B1 (en) 1993-12-22 1993-12-22 PEPTIDE WITH ACTIVITY AS A SUBSTRATE AND/OR INHIBITOR OF THE ENZYME TRANSGLUTAMINASE AND ITS USE IN DIAGNOSIS AND THERAPY.

Publications (3)

Publication Number Publication Date
ITRM930845A0 ITRM930845A0 (en) 1993-12-22
ITRM930845A1 ITRM930845A1 (en) 1995-06-22
IT1264084B1 true IT1264084B1 (en) 1996-09-10

Family

ID=11402105

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93RM000845A IT1264084B1 (en) 1993-12-22 1993-12-22 PEPTIDE WITH ACTIVITY AS A SUBSTRATE AND/OR INHIBITOR OF THE ENZYME TRANSGLUTAMINASE AND ITS USE IN DIAGNOSIS AND THERAPY.

Country Status (3)

Country Link
AU (1) AU1279895A (en)
IT (1) IT1264084B1 (en)
WO (1) WO1995017426A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9509271D0 (en) * 1995-05-05 1995-06-28 Biopharm Res & Dev Ltd Blood clot stabilisation inhibitors
WO1999007739A2 (en) * 1997-08-06 1999-02-18 The Rockefeller University Dna encoding the human synapsin iii gene and uses thereof
EP1201136A1 (en) 2000-10-31 2002-05-02 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO Food grade transglutaminase inhibitor and uses thereof

Also Published As

Publication number Publication date
AU1279895A (en) 1995-07-10
ITRM930845A0 (en) 1993-12-22
WO1995017426A1 (en) 1995-06-29
ITRM930845A1 (en) 1995-06-22

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Legal Events

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0001 Granted