IT1263744B - Derivati della taurina ad attivita' anti-aggregante piastrinica, procedimento per la loro preparazione e composizioni farmaceutiche cheli contengono - Google Patents
Derivati della taurina ad attivita' anti-aggregante piastrinica, procedimento per la loro preparazione e composizioni farmaceutiche cheli contengonoInfo
- Publication number
- IT1263744B IT1263744B ITMI930054A ITMI930054A IT1263744B IT 1263744 B IT1263744 B IT 1263744B IT MI930054 A ITMI930054 A IT MI930054A IT MI930054 A ITMI930054 A IT MI930054A IT 1263744 B IT1263744 B IT 1263744B
- Authority
- IT
- Italy
- Prior art keywords
- cheli
- procedure
- contain
- preparation
- pharmaceutical compositions
- Prior art date
Links
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical class NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 title abstract 4
- 241000024244 Chelis Species 0.000 title 1
- 230000002744 anti-aggregatory effect Effects 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- -1 5'-phosphopyridoxylidentaurine Chemical compound 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 230000004931 aggregating effect Effects 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 230000000702 anti-platelet effect Effects 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- NGVDGCNFYWLIFO-UHFFFAOYSA-N pyridoxal 5'-phosphate Chemical compound CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O NGVDGCNFYWLIFO-UHFFFAOYSA-N 0.000 abstract 1
- 235000007682 pyridoxal 5'-phosphate Nutrition 0.000 abstract 1
- 239000011589 pyridoxal 5'-phosphate Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 229960003080 taurine Drugs 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 229910052723 transition metal Inorganic materials 0.000 abstract 1
- 150000003624 transition metals Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La 5'-fosfopiridossilidentaurina ed i suoi complessi con metalli alcalini, alcalino-terrosi e di transizione mostrano eccellenti proprietà anti-aggreganti piastriniche, per cui trovano applicazione nella terapia e nella prevenzione della trombosi sia nell'uomo che nell'animale.Per la preparazione del derivato della taurina si portano a reagire a caldo in soluzione acquosa taurina e piridossale 5'-fosfato, mentre per l'ottenimento dei sali complessi la reazione procede nello stesso modo salvo che alla soluzione acquosa si aggiungono quantità stechiometriche di un sale del metallo desiderato.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI930054A IT1263744B (it) | 1993-01-18 | 1993-01-18 | Derivati della taurina ad attivita' anti-aggregante piastrinica, procedimento per la loro preparazione e composizioni farmaceutiche cheli contengono |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI930054A IT1263744B (it) | 1993-01-18 | 1993-01-18 | Derivati della taurina ad attivita' anti-aggregante piastrinica, procedimento per la loro preparazione e composizioni farmaceutiche cheli contengono |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI930054A0 ITMI930054A0 (it) | 1993-01-18 |
| ITMI930054A1 ITMI930054A1 (it) | 1994-07-18 |
| IT1263744B true IT1263744B (it) | 1996-08-27 |
Family
ID=11364661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI930054A IT1263744B (it) | 1993-01-18 | 1993-01-18 | Derivati della taurina ad attivita' anti-aggregante piastrinica, procedimento per la loro preparazione e composizioni farmaceutiche cheli contengono |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1263744B (it) |
-
1993
- 1993-01-18 IT ITMI930054A patent/IT1263744B/it active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI930054A1 (it) | 1994-07-18 |
| ITMI930054A0 (it) | 1993-01-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19961127 |