IT1262976B - Oligonucleotidi antisenso e loro uso - Google Patents
Oligonucleotidi antisenso e loro usoInfo
- Publication number
- IT1262976B IT1262976B ITRM920605A ITRM920605A IT1262976B IT 1262976 B IT1262976 B IT 1262976B IT RM920605 A ITRM920605 A IT RM920605A IT RM920605 A ITRM920605 A IT RM920605A IT 1262976 B IT1262976 B IT 1262976B
- Authority
- IT
- Italy
- Prior art keywords
- function
- cells
- antisense oligonucleotides
- compound
- inhibiting
- Prior art date
Links
- 108020000948 Antisense Oligonucleotides Proteins 0.000 title 1
- 239000000074 antisense oligonucleotide Substances 0.000 title 1
- 238000012230 antisense oligonucleotides Methods 0.000 title 1
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 abstract 2
- 108010092262 T-Cell Antigen Receptors Proteins 0.000 abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000006870 function Effects 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000008827 biological function Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 230000002452 interceptive effect Effects 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Uso di un composto che è antisenso rispetto all'RNA messaggero per la proteina che forma il recettore per l'antigene delle cellule T (TCR), e che è pertanto capace di inibire sostanzialmente la funzione biologica del riconoscimento dell'antigene in T linfociti, o di inibire selettivamente la stessa funzione biologica di solo una sottopopolazione di tali cellule, senza interferire con la funzione delle restanti T cellule, per la fabbricazione di un medicamento per uso immunologico.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM920605A IT1262976B (it) | 1992-08-14 | 1992-08-14 | Oligonucleotidi antisenso e loro uso |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM920605A IT1262976B (it) | 1992-08-14 | 1992-08-14 | Oligonucleotidi antisenso e loro uso |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITRM920605A0 ITRM920605A0 (it) | 1992-08-14 |
| ITRM920605A1 ITRM920605A1 (it) | 1994-02-14 |
| IT1262976B true IT1262976B (it) | 1996-07-23 |
Family
ID=11401158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITRM920605A IT1262976B (it) | 1992-08-14 | 1992-08-14 | Oligonucleotidi antisenso e loro uso |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1262976B (it) |
-
1992
- 1992-08-14 IT ITRM920605A patent/IT1262976B/it active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ITRM920605A0 (it) | 1992-08-14 |
| ITRM920605A1 (it) | 1994-02-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |