IT1252235B - Eseroline derivatives having anticholinesterase activity, process for their preparation and pharmaceutical compositions containing them - Google Patents
Eseroline derivatives having anticholinesterase activity, process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IT1252235B IT1252235B ITMI913398A ITMI913398A IT1252235B IT 1252235 B IT1252235 B IT 1252235B IT MI913398 A ITMI913398 A IT MI913398A IT MI913398 A ITMI913398 A IT MI913398A IT 1252235 B IT1252235 B IT 1252235B
- Authority
- IT
- Italy
- Prior art keywords
- pharmaceutical compositions
- preparation
- compositions containing
- anticholinesterase activity
- divalent
- Prior art date
Links
- 239000000544 cholinesterase inhibitor Substances 0.000 title abstract 2
- HKGWQUVGHPDEBZ-OLZOCXBDSA-N eseroline Chemical class C1=C(O)C=C2[C@]3(C)CCN(C)[C@@H]3N(C)C2=C1 HKGWQUVGHPDEBZ-OLZOCXBDSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- -1 alkyl radical Chemical class 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The preparation process and pharmaceutical compositions of derivatives of eseroline having anticholinesterase activity of general formula I: <IMAGE> where HY is a pharmaceutically acceptable organic or inorganic acid, R is selected from: R'OM, R'-O-A, R'-O-B, R' is H, or CH3-(L)m-CO-, where L is a straight or branched C1-C20 divalent alkyl radical which may contain one or more ethylenic unsaturations, M is a straight or branched 1 to 20 carbon atom divalent alkyl radical which may be substituted with aryl groups, A is a C3-C7 divalent alicyclic radical, B is a divalent aryl radical, n is a whole number from 1 to 20 and m is 0 or 1, and x is 0, 1 or 2 are described.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI913398A IT1252235B (en) | 1991-12-18 | 1991-12-18 | Eseroline derivatives having anticholinesterase activity, process for their preparation and pharmaceutical compositions containing them |
EP19920107866 EP0513703A3 (en) | 1991-05-13 | 1992-05-11 | Carbamate esters of eseroline having anticholinesterase activity, a process for their preparation and relative pharmaceutical compositions containing them as the active principle |
CA 2068501 CA2068501A1 (en) | 1991-05-13 | 1992-05-12 | Carbamate esters of eseroline having anticholinesterase activity, a process for their preparation and relative pharmaceutical compositions containing them as the active principle |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI913398A IT1252235B (en) | 1991-12-18 | 1991-12-18 | Eseroline derivatives having anticholinesterase activity, process for their preparation and pharmaceutical compositions containing them |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI913398A0 ITMI913398A0 (en) | 1991-12-18 |
ITMI913398A1 ITMI913398A1 (en) | 1993-06-18 |
IT1252235B true IT1252235B (en) | 1995-06-05 |
Family
ID=11361369
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI913398A IT1252235B (en) | 1991-05-13 | 1991-12-18 | Eseroline derivatives having anticholinesterase activity, process for their preparation and pharmaceutical compositions containing them |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1252235B (en) |
-
1991
- 1991-12-18 IT ITMI913398A patent/IT1252235B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ITMI913398A0 (en) | 1991-12-18 |
ITMI913398A1 (en) | 1993-06-18 |
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Legal Events
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0001 | Granted |