IT1248979B - Process for the production of surfactin - Google Patents
Process for the production of surfactinInfo
- Publication number
- IT1248979B IT1248979B IT02073890A IT2073890A IT1248979B IT 1248979 B IT1248979 B IT 1248979B IT 02073890 A IT02073890 A IT 02073890A IT 2073890 A IT2073890 A IT 2073890A IT 1248979 B IT1248979 B IT 1248979B
- Authority
- IT
- Italy
- Prior art keywords
- surfactin
- production
- strain
- iso
- lodged
- Prior art date
Links
- AFWTZXXDGQBIKW-UHFFFAOYSA-N C14 surfactin Natural products CCCCCCCCCCCC1CC(=O)NC(CCC(O)=O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CC(O)=O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)O1 AFWTZXXDGQBIKW-UHFFFAOYSA-N 0.000 title abstract 4
- NJGWOFRZMQRKHT-UHFFFAOYSA-N surfactin Natural products CC(C)CCCCCCCCCC1CC(=O)NC(CCC(O)=O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CC(O)=O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)O1 NJGWOFRZMQRKHT-UHFFFAOYSA-N 0.000 title abstract 4
- NJGWOFRZMQRKHT-WGVNQGGSSA-N surfactin C Chemical compound CC(C)CCCCCCCCC[C@@H]1CC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O1 NJGWOFRZMQRKHT-WGVNQGGSSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 235000014469 Bacillus subtilis Nutrition 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000002703 mutagenesis Methods 0.000 abstract 1
- 231100000350 mutagenesis Toxicity 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
A new strain of B. subtilis obtained by mutagenesis from the wild type strain lodged as ATCC 55033 and its use in the production of surfactin is described. The use of this stable mutant in this process makes it possible to obtain purified surfactin in higher yields than from the parent strain. The surfactin so produced comprises an amino acid portion formed by a heptapeptide ring linked to a mixture of β-saturated fatty acids whose carbon chains have a number of carbon atoms varying from 13 to 15 and a normal, iso and anti-iso structure. <IMAGE>
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02073890A IT1248979B (en) | 1990-06-22 | 1990-06-22 | Process for the production of surfactin |
EP91108749A EP0463393B1 (en) | 1990-06-22 | 1991-05-29 | A mutant of bacillus subtiles and a method of producing surfactin with the use of the mutant |
AT91108749T ATE130314T1 (en) | 1990-06-22 | 1991-05-29 | BACILLUS SUBTILIS MUTANT AND METHOD FOR PRODUCING SURFACTIN BY USING THIS MUTANT. |
DE69114574T DE69114574T2 (en) | 1990-06-22 | 1991-05-29 | Bacillus subtilis mutant and method of producing surfactin by using this mutant. |
DK91108749.2T DK0463393T3 (en) | 1990-06-22 | 1991-05-29 | Mutant of bacillus subtilis and method of producing surfactin by the mutant |
ES91108749T ES2082039T3 (en) | 1990-06-22 | 1991-05-29 | A MUTANT OF BACILLUS SUBTILIS AND A METHOD FOR PRODUCING SURFACTIN USING THE MUTANT. |
US07/718,464 US5227294A (en) | 1990-06-22 | 1991-06-20 | Method of producing surfactin with the use of mutant of bacillus subtilis |
JP3175850A JP3030789B2 (en) | 1990-06-22 | 1991-06-21 | Bacillus subtilis mutant and method for producing surfactin by using the mutant |
US07/981,256 US5264363A (en) | 1990-06-22 | 1992-11-25 | Mutant of Bacillus subtilis |
GR950402987T GR3018098T3 (en) | 1990-06-22 | 1995-11-16 | A mutant of bacillus subtiles and a method of producing surfactin with the use of the mutant. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02073890A IT1248979B (en) | 1990-06-22 | 1990-06-22 | Process for the production of surfactin |
Publications (3)
Publication Number | Publication Date |
---|---|
IT9020738A0 IT9020738A0 (en) | 1990-06-22 |
IT9020738A1 IT9020738A1 (en) | 1991-12-22 |
IT1248979B true IT1248979B (en) | 1995-02-11 |
Family
ID=11171313
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT02073890A IT1248979B (en) | 1990-06-22 | 1990-06-22 | Process for the production of surfactin |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1248979B (en) |
-
1990
- 1990-06-22 IT IT02073890A patent/IT1248979B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
IT9020738A1 (en) | 1991-12-22 |
IT9020738A0 (en) | 1990-06-22 |
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