IT1248055B - Arginine derivatives and process for their preparation - Google Patents
Arginine derivatives and process for their preparationInfo
- Publication number
- IT1248055B IT1248055B ITMI911633A ITMI911633A IT1248055B IT 1248055 B IT1248055 B IT 1248055B IT MI911633 A ITMI911633 A IT MI911633A IT MI911633 A ITMI911633 A IT MI911633A IT 1248055 B IT1248055 B IT 1248055B
- Authority
- IT
- Italy
- Prior art keywords
- preparation
- arginine
- boc
- bis
- arginine derivatives
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 150000001483 arginine derivatives Chemical class 0.000 title 1
- 239000004475 Arginine Substances 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960003104 ornithine Drugs 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- UQJXXWHAJKRDKY-UHFFFAOYSA-N tert-butyl n-[[(2-methylpropan-2-yl)oxycarbonylamino]-methylsulfanylmethylidene]carbamate Chemical compound CC(C)(C)OC(=O)NC(SC)=NC(=O)OC(C)(C)C UQJXXWHAJKRDKY-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Process for the preparation of Nα-Z-Nω, Nω'-bis(Boc)-arginine and Nα-Fmoc-Nω, Nω'-bis(Boc)-arginine which comprises the reaction between Nα-Z-ornithine and N,N'-bis(Boc)-S-methyl- isothiourea, and in conversion of the Nα-Z-Nω, Nω'-bis(Boc)-arginine so obtained to the corresponding Nα-Fmoc derivative. The compounds are particularly useful in the synthesis of polypeptides.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI911633A IT1248055B (en) | 1991-06-13 | 1991-06-13 | Arginine derivatives and process for their preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI911633A IT1248055B (en) | 1991-06-13 | 1991-06-13 | Arginine derivatives and process for their preparation |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI911633A0 ITMI911633A0 (en) | 1991-06-13 |
ITMI911633A1 ITMI911633A1 (en) | 1992-12-13 |
IT1248055B true IT1248055B (en) | 1995-01-05 |
Family
ID=11360113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI911633A IT1248055B (en) | 1991-06-13 | 1991-06-13 | Arginine derivatives and process for their preparation |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1248055B (en) |
-
1991
- 1991-06-13 IT ITMI911633A patent/IT1248055B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ITMI911633A1 (en) | 1992-12-13 |
ITMI911633A0 (en) | 1991-06-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960610 |