IT1242000B - Use of tromethamine salts in calcitonin-based pharmaceutical compositions that can be administered by the nasal route in human therapeutic medicine. - Google Patents
Use of tromethamine salts in calcitonin-based pharmaceutical compositions that can be administered by the nasal route in human therapeutic medicine.Info
- Publication number
- IT1242000B IT1242000B IT48325A IT4832590A IT1242000B IT 1242000 B IT1242000 B IT 1242000B IT 48325 A IT48325 A IT 48325A IT 4832590 A IT4832590 A IT 4832590A IT 1242000 B IT1242000 B IT 1242000B
- Authority
- IT
- Italy
- Prior art keywords
- calcitonin
- administered
- pharmaceutical compositions
- nasal route
- human therapeutic
- Prior art date
Links
- 102000055006 Calcitonin Human genes 0.000 title abstract 2
- 108060001064 Calcitonin Proteins 0.000 title abstract 2
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 title abstract 2
- 229960004015 calcitonin Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical class OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000012062 aqueous buffer Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000002270 dispersing agent Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention relates to pharmaceutical compositions that can be administered by the nasal route, comprising: a) calcitonin; b) an antibacterial preservative; c) an appropriate aqueous buffer, made up of tromethamine salts, having properties activating the absorption of the active principle; d) various additives belonging to the class of the surfactants, dispersants, carriers, etc., can also be used.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT48325A IT1242000B (en) | 1990-10-01 | 1990-10-01 | Use of tromethamine salts in calcitonin-based pharmaceutical compositions that can be administered by the nasal route in human therapeutic medicine. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT48325A IT1242000B (en) | 1990-10-01 | 1990-10-01 | Use of tromethamine salts in calcitonin-based pharmaceutical compositions that can be administered by the nasal route in human therapeutic medicine. |
Publications (3)
Publication Number | Publication Date |
---|---|
IT9048325A0 IT9048325A0 (en) | 1990-10-01 |
IT9048325A1 IT9048325A1 (en) | 1992-04-01 |
IT1242000B true IT1242000B (en) | 1994-02-02 |
Family
ID=11265905
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT48325A IT1242000B (en) | 1990-10-01 | 1990-10-01 | Use of tromethamine salts in calcitonin-based pharmaceutical compositions that can be administered by the nasal route in human therapeutic medicine. |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1242000B (en) |
-
1990
- 1990-10-01 IT IT48325A patent/IT1242000B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
IT9048325A1 (en) | 1992-04-01 |
IT9048325A0 (en) | 1990-10-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19961029 |