IT1237510B - Tranquiliser compounds made through 7-chlorine-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4 benzodiazepine-2-one with cyclodextrin complexes, their preparation and relative pharmaceutical composition. - Google Patents

Tranquiliser compounds made through 7-chlorine-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4 benzodiazepine-2-one with cyclodextrin complexes, their preparation and relative pharmaceutical composition.

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Publication number
IT1237510B
IT1237510B IT02220089A IT2220089A IT1237510B IT 1237510 B IT1237510 B IT 1237510B IT 02220089 A IT02220089 A IT 02220089A IT 2220089 A IT2220089 A IT 2220089A IT 1237510 B IT1237510 B IT 1237510B
Authority
IT
Italy
Prior art keywords
benzodiazepine
chlorophenyl
dihydro
chlorine
hydroxy
Prior art date
Application number
IT02220089A
Other languages
Italian (it)
Other versions
IT8922200A0 (en
IT8922200A1 (en
Inventor
Laura Puricelli
Original Assignee
Magis Farmaceutici
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Magis Farmaceutici filed Critical Magis Farmaceutici
Priority to IT02220089A priority Critical patent/IT1237510B/en
Publication of IT8922200A0 publication Critical patent/IT8922200A0/en
Publication of IT8922200A1 publication Critical patent/IT8922200A1/en
Application granted granted Critical
Publication of IT1237510B publication Critical patent/IT1237510B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Compounds made by mixing 7-chlorine-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4 benzodiazepine-2-one with a cyclodextrin chosen between α, β, γ, dimethyl-β, or hydroxypropyl-β cyclodextrin.The above-mentioned compound offers better tranquilizer, hypnotic, muscle relaxant and anticonvulsant effects in respect to the corresponding starting qualities administered as such, and better stability compared to similar products.
IT02220089A 1989-10-31 1989-10-31 Tranquiliser compounds made through 7-chlorine-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4 benzodiazepine-2-one with cyclodextrin complexes, their preparation and relative pharmaceutical composition. IT1237510B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IT02220089A IT1237510B (en) 1989-10-31 1989-10-31 Tranquiliser compounds made through 7-chlorine-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4 benzodiazepine-2-one with cyclodextrin complexes, their preparation and relative pharmaceutical composition.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02220089A IT1237510B (en) 1989-10-31 1989-10-31 Tranquiliser compounds made through 7-chlorine-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4 benzodiazepine-2-one with cyclodextrin complexes, their preparation and relative pharmaceutical composition.

Publications (3)

Publication Number Publication Date
IT8922200A0 IT8922200A0 (en) 1989-10-31
IT8922200A1 IT8922200A1 (en) 1991-05-01
IT1237510B true IT1237510B (en) 1993-06-08

Family

ID=11192957

Family Applications (1)

Application Number Title Priority Date Filing Date
IT02220089A IT1237510B (en) 1989-10-31 1989-10-31 Tranquiliser compounds made through 7-chlorine-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4 benzodiazepine-2-one with cyclodextrin complexes, their preparation and relative pharmaceutical composition.

Country Status (1)

Country Link
IT (1) IT1237510B (en)

Also Published As

Publication number Publication date
IT8922200A0 (en) 1989-10-31
IT8922200A1 (en) 1991-05-01

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IT1237510B (en) Tranquiliser compounds made through 7-chlorine-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4 benzodiazepine-2-one with cyclodextrin complexes, their preparation and relative pharmaceutical composition.

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