IT1226143B - New 1,2-di-O-acyl glycero-phosphate ester(s) of L-carnitine - Google Patents
New 1,2-di-O-acyl glycero-phosphate ester(s) of L-carnitineInfo
- Publication number
- IT1226143B IT1226143B IT8821188A IT2118888A IT1226143B IT 1226143 B IT1226143 B IT 1226143B IT 8821188 A IT8821188 A IT 8821188A IT 2118888 A IT2118888 A IT 2118888A IT 1226143 B IT1226143 B IT 1226143B
- Authority
- IT
- Italy
- Prior art keywords
- carnitine
- new
- phosphate ester
- acyl glycero
- glycero
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 2
- AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 title 1
- BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- RLOWWWKZYUNIDI-UHFFFAOYSA-N phosphinic chloride Chemical compound ClP=O RLOWWWKZYUNIDI-UHFFFAOYSA-N 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
Abstract
L-Carnitre derivs of formula (I) are new R and R1 = 2.22C opt. unsatd acid radical; R2 = H or 1-5C alkyl X = anion of hydrochloric, phosphoric, hydrobromic or sulphuric acid; l = 0-1; m and n = 0-1; provided that (i) when m = l n = l; and (2) when m = O, the O carries on negative charge and n = O. (I) are prepd. from L-carnitine (ester) by reaction with (PhO2) POCl to give (II) which is hydrolysed.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8821188A IT1226143B (en) | 1988-07-01 | 1988-07-01 | New 1,2-di-O-acyl glycero-phosphate ester(s) of L-carnitine |
| EP89111591A EP0348859A1 (en) | 1988-07-01 | 1989-06-26 | 1,2-di-O-acyl glycero(DI)phosphate of L-carnitine and its derivatives, a process for their preparation and pharmaceutical formulations which contain them |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8821188A IT1226143B (en) | 1988-07-01 | 1988-07-01 | New 1,2-di-O-acyl glycero-phosphate ester(s) of L-carnitine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8821188A0 IT8821188A0 (en) | 1988-07-01 |
| IT1226143B true IT1226143B (en) | 1990-12-19 |
Family
ID=11178105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8821188A IT1226143B (en) | 1988-07-01 | 1988-07-01 | New 1,2-di-O-acyl glycero-phosphate ester(s) of L-carnitine |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1226143B (en) |
-
1988
- 1988-07-01 IT IT8821188A patent/IT1226143B/en active
Also Published As
| Publication number | Publication date |
|---|---|
| IT8821188A0 (en) | 1988-07-01 |
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