IT1214764B - New neuronotrophic factor from brain caudate nuclei - Google Patents
New neuronotrophic factor from brain caudate nucleiInfo
- Publication number
- IT1214764B IT1214764B IT8648782A IT4878286A IT1214764B IT 1214764 B IT1214764 B IT 1214764B IT 8648782 A IT8648782 A IT 8648782A IT 4878286 A IT4878286 A IT 4878286A IT 1214764 B IT1214764 B IT 1214764B
- Authority
- IT
- Italy
- Prior art keywords
- new
- ntf
- mol
- neuronotrophic factor
- caudate nuclei
- Prior art date
Links
- 108010025020 Nerve Growth Factor Proteins 0.000 title abstract 5
- 102000007072 Nerve Growth Factors Human genes 0.000 title abstract 5
- 210000004556 brain Anatomy 0.000 title 1
- 239000006228 supernatant Substances 0.000 abstract 2
- 101710093543 Probable non-specific lipid-transfer protein Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000005194 fractionation Methods 0.000 abstract 1
- 210000005171 mammalian brain Anatomy 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 230000001228 trophic effect Effects 0.000 abstract 1
Landscapes
- Peptides Or Proteins (AREA)
Abstract
Prepn. of neuronotrophic factor (NTF) comprises (1) homogenising mammalian brain tissue; (2) acid pptn. of the homogenate; (3) dialysing the supernatant through a membrane of mol. wt. restriction 5-10 kD and (4) chromatographic fractionation of the dialysed supernatant to separate components according to mol. wt. NTF, which is a basic protein of mol. wt. about 14400, is claimed to be new. Pref. NTF has isoelectric point about 10 and specific activity at least 0.01mg/trophic unit.
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8648782A IT1214764B (en) | 1986-12-23 | 1986-12-23 | New neuronotrophic factor from brain caudate nuclei |
| EP87401795A EP0258111A3 (en) | 1986-08-07 | 1987-07-31 | Novel neuronotrophic factor |
| IL83398A IL83398A0 (en) | 1986-08-07 | 1987-07-31 | Novel neuronotrophic factor |
| NZ221313A NZ221313A (en) | 1986-08-07 | 1987-08-03 | Neuronotrophic factor (14 400 daltons) derived from mammalian brain tissue and compositions containing it |
| PH35621A PH23838A (en) | 1986-08-07 | 1987-08-04 | Purification,characterisation and application of a new neurotrophic factor derived from mammalian brain |
| FI873415A FI873415A7 (en) | 1986-08-07 | 1987-08-06 | Method for preparing a novel neurotropic factor. |
| DK410887A DK410887A (en) | 1986-08-07 | 1987-08-06 | PROTEIN ISOLATED FROM mammalian brain tissue |
| PT85498A PT85498B (en) | 1986-08-07 | 1987-08-06 | METHOD FOR PREPARING A NEW NEURONOTROFIC FACTOR AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM |
| NO873285A NO873285L (en) | 1986-08-07 | 1987-08-06 | NEW NEURONOTROPY - FACTOR. |
| AU76616/87A AU602925C (en) | 1986-08-07 | 1987-08-06 | Novel neuronotrophic factor |
| CN198787105478A CN87105478A (en) | 1986-08-07 | 1987-08-07 | Novel Neurotrophic Factors |
| YU01490/87A YU149087A (en) | 1986-08-07 | 1987-08-07 | Process for obtaining new neuronotrophic factor |
| PL1987267240A PL151701B1 (en) | 1986-08-07 | 1987-08-07 | Novel neuronotrophic factor |
| KR1019870008687A KR880002533A (en) | 1986-08-07 | 1987-08-07 | Neuropathic factor |
| HU873594A HU202558B (en) | 1986-08-07 | 1987-08-07 | Process for isolating neuronotrophic factor and for producing pharmaceutical composition containing them |
| AR87308375A AR243203A1 (en) | 1986-08-07 | 1987-08-07 | A PROCEDURE FOR PREPARING A NEURONOTROPHIC FACTOR. |
| US07/562,024 US5218094A (en) | 1986-08-07 | 1990-08-02 | Neuronotrophic factor derived from mammalian brain tissue |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8648782A IT1214764B (en) | 1986-12-23 | 1986-12-23 | New neuronotrophic factor from brain caudate nuclei |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8648782A0 IT8648782A0 (en) | 1986-12-23 |
| IT1214764B true IT1214764B (en) | 1990-01-18 |
Family
ID=11268534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8648782A IT1214764B (en) | 1986-08-07 | 1986-12-23 | New neuronotrophic factor from brain caudate nuclei |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1214764B (en) |
-
1986
- 1986-12-23 IT IT8648782A patent/IT1214764B/en active
Also Published As
| Publication number | Publication date |
|---|---|
| IT8648782A0 (en) | 1986-12-23 |
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