IT1213288B - Pharmacological use of di:phenyl-iodonium cpds. - Google Patents
Pharmacological use of di:phenyl-iodonium cpds.Info
- Publication number
- IT1213288B IT1213288B IT8449122A IT4912284A IT1213288B IT 1213288 B IT1213288 B IT 1213288B IT 8449122 A IT8449122 A IT 8449122A IT 4912284 A IT4912284 A IT 4912284A IT 1213288 B IT1213288 B IT 1213288B
- Authority
- IT
- Italy
- Prior art keywords
- phenyl
- cpds
- iodonium
- pharmacological use
- agent
- Prior art date
Links
- 230000000144 pharmacologic effect Effects 0.000 title 1
- KTNLYTNKBOKXRW-UHFFFAOYSA-N phenyliodanium Chemical compound [IH+]C1=CC=CC=C1 KTNLYTNKBOKXRW-UHFFFAOYSA-N 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- ZOOGRGPOEVQQDX-UUOKFMHZSA-N 3',5'-cyclic GMP Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-UUOKFMHZSA-N 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 210000000748 cardiovascular system Anatomy 0.000 abstract 1
- 230000003028 elevating effect Effects 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 230000002107 myocardial effect Effects 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Method for elevating intracellular cGMP levels in vivo or treating the cardiovascular system to enhance myocardial contractility comprises admin. of an agent of formula (I) or (II) where Ar and Ar'= phenyl opt. substd. by Me, Et, Bu and/or tBu gp(s). Pref. agent is present with an anion derived from a pharmaceutically acceptable inorganic or organic acid.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54960383A | 1983-11-07 | 1983-11-07 | |
| US06/668,810 US4623666A (en) | 1984-11-06 | 1984-11-06 | Pharmacological applications of diphenylhalonium ion |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8449122A0 IT8449122A0 (en) | 1984-11-06 |
| IT1213288B true IT1213288B (en) | 1989-12-14 |
Family
ID=27069183
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8449122A IT1213288B (en) | 1983-11-07 | 1984-11-06 | Pharmacological use of di:phenyl-iodonium cpds. |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1213288B (en) |
-
1984
- 1984-11-06 IT IT8449122A patent/IT1213288B/en active
Also Published As
| Publication number | Publication date |
|---|---|
| IT8449122A0 (en) | 1984-11-06 |
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