IT1206322B - Methyl-bis:di:methoxy-phenyl-ethylamine - Google Patents

Methyl-bis:di:methoxy-phenyl-ethylamine

Info

Publication number
IT1206322B
IT1206322B IT8320838A IT2083883A IT1206322B IT 1206322 B IT1206322 B IT 1206322B IT 8320838 A IT8320838 A IT 8320838A IT 2083883 A IT2083883 A IT 2083883A IT 1206322 B IT1206322 B IT 1206322B
Authority
IT
Italy
Prior art keywords
bis
methyl
ethylamine
methoxy
phenyl
Prior art date
Application number
IT8320838A
Other languages
Italian (it)
Other versions
IT8320838A0 (en
Inventor
Giuseppe Quadro
Jean Cahn
Original Assignee
Yason Srl
Sir International Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yason Srl, Sir International Sa filed Critical Yason Srl
Publication of IT8320838A0 publication Critical patent/IT8320838A0/en
Priority to IT8320838A priority Critical patent/IT1206322B/en
Priority to CH3684/83A priority patent/CH654294A5/en
Priority to CA000431900A priority patent/CA1238858A/en
Priority to GB08318467A priority patent/GB2126213B/en
Priority to ES524353A priority patent/ES8500885A1/en
Priority to FR8311387A priority patent/FR2541113B1/en
Priority to DE3324727A priority patent/DE3324727A1/en
Priority to NLAANVRAGE8302451,A priority patent/NL185666C/en
Priority to US06/691,157 priority patent/US4956389A/en
Application granted granted Critical
Publication of IT1206322B publication Critical patent/IT1206322B/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

N-Methyl-N,N-bis (3,4-dimethoxy-phenylethyl) amine of formula (I) and its acid-addn. salts is new. (I) may be prepd. by reductive methylation of bis(3,4-dimethoxyphenylethyl)amine (II) with HCHO in a reducing medium. (I) is a calcium antagonist with comparable activity to nifedipin, e.g. useful for treating myocardial ischemia and cerebrovascular disorders. Effective oral doses are 20-150 mg/day. (FL)
IT8320838A 1982-07-09 1983-04-28 Methyl-bis:di:methoxy-phenyl-ethylamine IT1206322B (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT8320838A IT1206322B (en) 1983-04-28 1983-04-28 Methyl-bis:di:methoxy-phenyl-ethylamine
CH3684/83A CH654294A5 (en) 1982-07-09 1983-07-05 CARDIAC AND CEREBRAL LEVEL CALCIUM BLOCKING COMPOUNDS, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS.
CA000431900A CA1238858A (en) 1982-07-09 1983-07-06 Pharmaceutical compositions having calcium blocking activity
GB08318467A GB2126213B (en) 1982-07-09 1983-07-07 Calcium blocking bis(methoxyphenyl)amine
ES524353A ES8500885A1 (en) 1982-07-09 1983-07-08 Compounds having calcium blocking activity
FR8311387A FR2541113B1 (en) 1982-07-09 1983-07-08 THERAPEUTIC APPLICATION OF N-METHYL-N-BIS (3,4-DIMETHOXYPHENYLETHYL) AMINE AND ITS ADDITION SALTS WITH PHARMACEUTICALLY ACCEPTABLE ACIDS
DE3324727A DE3324727A1 (en) 1982-07-09 1983-07-08 N-METHYL-N-BIS- (3,4-DIMETHOXYPHENYLAETHYL) AMINE, ITS SALTS WITH ACIDS, MEDICINAL PRODUCTS AND ITS USE IN THE TREATMENT OF CARDIOVASCULAR DISEASES AND CERBRAL BLOOD DISEASES
NLAANVRAGE8302451,A NL185666C (en) 1982-07-09 1983-07-08 PHARMACEUTICAL PREPARATION OR ARTICLE AND MEDICINAL COMPOUNDS.
US06/691,157 US4956389A (en) 1982-07-09 1985-01-14 Compounds having calcium blocking activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8320838A IT1206322B (en) 1983-04-28 1983-04-28 Methyl-bis:di:methoxy-phenyl-ethylamine

Publications (2)

Publication Number Publication Date
IT8320838A0 IT8320838A0 (en) 1983-04-28
IT1206322B true IT1206322B (en) 1989-04-14

Family

ID=11172807

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8320838A IT1206322B (en) 1982-07-09 1983-04-28 Methyl-bis:di:methoxy-phenyl-ethylamine

Country Status (1)

Country Link
IT (1) IT1206322B (en)

Also Published As

Publication number Publication date
IT8320838A0 (en) 1983-04-28

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Effective date: 19950427