IT1206281B - Tissue plasminogen activator to remove blood clots - Google Patents
Tissue plasminogen activator to remove blood clotsInfo
- Publication number
- IT1206281B IT1206281B IT8747915A IT4791587A IT1206281B IT 1206281 B IT1206281 B IT 1206281B IT 8747915 A IT8747915 A IT 8747915A IT 4791587 A IT4791587 A IT 4791587A IT 1206281 B IT1206281 B IT 1206281B
- Authority
- IT
- Italy
- Prior art keywords
- plasminogen activator
- tissue
- pref
- tissue plasminogen
- blood clots
- Prior art date
Links
- 102000003978 Tissue Plasminogen Activator Human genes 0.000 title abstract 6
- 108090000373 Tissue Plasminogen Activator Proteins 0.000 title abstract 6
- 229960000187 tissue plasminogen activator Drugs 0.000 title abstract 6
- 208000007536 Thrombosis Diseases 0.000 title 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical group [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000002107 myocardial effect Effects 0.000 abstract 1
- 230000010410 reperfusion Effects 0.000 abstract 1
Abstract
(A) Tissue plasminogen activator (t-PA) can be used in the prepn. of a pharmaceutical to inhibit damage of endangered tissue during blood reperfusion in mammals. (B) A combination of t-PA and superoxide desmutase (SOD) is new. The tissue to be protected is esp. myocardial tissue. Pref. the t-PA is in single or double chain form. The t-PA pref. has a specific amino acid sequence. Pref. the SOD is the copper/zinc form from cow or human origin.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86204686A | 1986-05-12 | 1986-05-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8747915A0 IT8747915A0 (en) | 1987-05-12 |
IT1206281B true IT1206281B (en) | 1989-04-14 |
Family
ID=25337493
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT8747915A IT1206281B (en) | 1986-05-12 | 1987-05-12 | Tissue plasminogen activator to remove blood clots |
Country Status (2)
Country | Link |
---|---|
IT (1) | IT1206281B (en) |
ZA (1) | ZA873351B (en) |
-
1987
- 1987-05-11 ZA ZA873351A patent/ZA873351B/en unknown
- 1987-05-12 IT IT8747915A patent/IT1206281B/en active
Also Published As
Publication number | Publication date |
---|---|
ZA873351B (en) | 1988-12-28 |
IT8747915A0 (en) | 1987-05-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19940418 |