IT1205014B - New nootropic N-substd. isoxazole-5-carboxamide(s) - Google Patents

New nootropic N-substd. isoxazole-5-carboxamide(s)

Info

Publication number
IT1205014B
IT1205014B IT20589/87A IT2058987A IT1205014B IT 1205014 B IT1205014 B IT 1205014B IT 20589/87 A IT20589/87 A IT 20589/87A IT 2058987 A IT2058987 A IT 2058987A IT 1205014 B IT1205014 B IT 1205014B
Authority
IT
Italy
Prior art keywords
substd
isoxazole
alkyl
carboxamide
alkoxy
Prior art date
Application number
IT20589/87A
Other languages
Italian (it)
Other versions
IT8720589A0 (en
Inventor
Angelo Carenzi
Dario Chiarino
Bella Davide Della
Mauro Napoletano
Alberto Sala
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of IT8720589A0 publication Critical patent/IT8720589A0/en
Priority to IT20589/87A priority Critical patent/IT1205014B/en
Priority to JP63504091A priority patent/JPH02500365A/en
Priority to AT88904406T priority patent/ATE65997T1/en
Priority to PCT/EP1988/000445 priority patent/WO1988009330A1/en
Priority to DE8888904406T priority patent/DE3864124D1/en
Priority to AU17869/88A priority patent/AU599809B2/en
Priority to US07/302,747 priority patent/US4985428A/en
Priority to EP88904406A priority patent/EP0317588B1/en
Priority to DK004389A priority patent/DK4389A/en
Priority to FI890173A priority patent/FI89266C/en
Priority to NO890245A priority patent/NO172120C/en
Application granted granted Critical
Publication of IT1205014B publication Critical patent/IT1205014B/en

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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Isoxazole cpds. of the formula (I) and their salts are new, where n is 1 or 2; R is H, halogen, 0H or 1-6C alkyl or alkoxy; R1 is 0H, opt. unsatd. 1-18C alkoxy or NR2R3; R2 and R3 are each independently H, 1-6C alkyl or -(CH2)mR4 where m is 1-3 and R4 is carboxy, (1-6C alkoxy)-carbonyl or NR5R6 in which R5 and R6 are each independently H or 1-6C alkyl; or one of R2 and R3 is -CHR4R7 where R7 is 1-4C alkyl opt. substd. by phenyl, 0H or SH, and the other is H; or -NR2R3 is a 5- to 7-membered heterocycle opt. further contg. one or two heteroatoms selected from 0,N and S.
IT20589/87A 1987-05-20 1987-05-20 New nootropic N-substd. isoxazole-5-carboxamide(s) IT1205014B (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT20589/87A IT1205014B (en) 1987-05-20 1987-05-20 New nootropic N-substd. isoxazole-5-carboxamide(s)
DE8888904406T DE3864124D1 (en) 1987-05-20 1988-05-19 ISOXAZOLES WITH NOOTROPICAL EFFECT.
AT88904406T ATE65997T1 (en) 1987-05-20 1988-05-19 ISOXAZOLE WITH NOOTROPIC ACTION.
PCT/EP1988/000445 WO1988009330A1 (en) 1987-05-20 1988-05-19 Isoxazoles with nootropic activity
JP63504091A JPH02500365A (en) 1987-05-20 1988-05-19 Compounds with cognitive aids
AU17869/88A AU599809B2 (en) 1987-05-20 1988-05-19 Isoxazoles with nootropic activity
US07/302,747 US4985428A (en) 1987-05-20 1988-05-19 Isoxazoles with nootropic activity
EP88904406A EP0317588B1 (en) 1987-05-20 1988-05-19 Isoxazoles with nootropic activity
DK004389A DK4389A (en) 1987-05-20 1989-01-06 ISOXAZOLES WITH NOOTROP EFFECT
FI890173A FI89266C (en) 1987-05-20 1989-01-13 FREQUENCY FRAME RELEASE WITH NOXROPICAL NETWORK
NO890245A NO172120C (en) 1987-05-20 1989-01-19 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ISOXAZOLS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20589/87A IT1205014B (en) 1987-05-20 1987-05-20 New nootropic N-substd. isoxazole-5-carboxamide(s)

Publications (2)

Publication Number Publication Date
IT8720589A0 IT8720589A0 (en) 1987-05-20
IT1205014B true IT1205014B (en) 1989-03-10

Family

ID=11169235

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20589/87A IT1205014B (en) 1987-05-20 1987-05-20 New nootropic N-substd. isoxazole-5-carboxamide(s)

Country Status (1)

Country Link
IT (1) IT1205014B (en)

Also Published As

Publication number Publication date
IT8720589A0 (en) 1987-05-20

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