IT1201425B - New platinum 1,4-di:amino-anthraquinone complexes - Google Patents
New platinum 1,4-di:amino-anthraquinone complexesInfo
- Publication number
- IT1201425B IT1201425B IT21324/85A IT2132485A IT1201425B IT 1201425 B IT1201425 B IT 1201425B IT 21324/85 A IT21324/85 A IT 21324/85A IT 2132485 A IT2132485 A IT 2132485A IT 1201425 B IT1201425 B IT 1201425B
- Authority
- IT
- Italy
- Prior art keywords
- complexes
- anthraquinone
- amino
- new platinum
- ch3soch3
- Prior art date
Links
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 title 2
- KHUFHLFHOQVFGB-UHFFFAOYSA-N 1-aminoanthracene-9,10-dione Chemical class O=C1C2=CC=CC=C2C(=O)C2=C1C=CC=C2N KHUFHLFHOQVFGB-UHFFFAOYSA-N 0.000 title 1
- 229910052697 platinum Inorganic materials 0.000 title 1
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 2
- FBMQNRKSAWNXBT-UHFFFAOYSA-N 1,4-diaminoanthracene-9,10-dione Chemical compound O=C1C2=CC=CC=C2C(=O)C2=C1C(N)=CC=C2N FBMQNRKSAWNXBT-UHFFFAOYSA-N 0.000 abstract 1
- 125000000022 2-aminoethyl group Chemical group [H]C([*])([H])C([H])([H])N([H])[H] 0.000 abstract 1
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 235000019439 ethyl acetate Nutrition 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Abstract
Complexes of formula cis-(L-(Pt(II)XX')m).(Solv)n (I), are claimed. In (I), X and X' = Cl, OH, CH3SOCH3.Cl or CH3SOCH3.OH; m = 1 or 2; n = 0, 1/2 or 1-6; Solv = H2O, 1-5C alcohol, MeCN or EtOAc; L = a bidentate 1,4-diaminoanthraquinone ligand of formula (II) or an acid-addn. salt of (II). Ra and Rb = H or OH; R1-R4 = H, 1-5C alkyl or (CH2)rOH; p and r = 2 or 3; or R1+R2 and R3+R4 = (CH2)xZ(CH2)y; Z = CH2 or O; x and y = 1 or 2. (N.B., specifically claimed cpds. include ones where R1 = 2-aminoethyl).
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21324/85A IT1201425B (en) | 1985-06-27 | 1985-06-27 | New platinum 1,4-di:amino-anthraquinone complexes |
| IL76002A IL76002A0 (en) | 1984-08-03 | 1985-08-01 | Amino-anthracenediones-platinum complexes useful as anti-cancer compounds |
| GR851903A GR851903B (en) | 1984-08-03 | 1985-08-02 | |
| NZ212976A NZ212976A (en) | 1984-08-03 | 1985-08-02 | Amino-anthracenedione-platinum complexes and anti-cancer compositions |
| AT85109732T ATE53587T1 (en) | 1984-08-03 | 1985-08-02 | AMINOANTHRACENDIONE PLATINUM COMPLEXES FOR ANTI-CANCER COMPOUNDS. |
| CA000488014A CA1251203A (en) | 1984-08-03 | 1985-08-02 | Amino-anthracenediones-platinum complexes useful as anti-cancer compounds |
| ES545861A ES8604248A1 (en) | 1984-08-03 | 1985-08-02 | Amino-anthracenediones-platinum complexes useful as anti-cancer compounds. |
| EP85109732A EP0170290B1 (en) | 1984-08-03 | 1985-08-02 | Amino-anthracenediones-platinum complexes useful as anti-cancer compounds |
| AU45733/85A AU571988B2 (en) | 1984-08-03 | 1985-08-02 | Amino-anthracenedione-platinum complexes |
| DE8585109732T DE3578180D1 (en) | 1984-08-03 | 1985-08-02 | AMINOANTHRACENDIONE-PLATINUM COMPLEXES FOR ANTI-CANCER COMPOUNDS. |
| HU852973A HU193339B (en) | 1984-08-03 | 1985-08-02 | Process for producing amino-anthracene-dion-platinum-complexes |
| US06/761,787 US4732893A (en) | 1984-08-03 | 1985-08-02 | Amino-anthracenediones-platinum complexes useful as anticancer compounds |
| DK352285A DK352285A (en) | 1984-08-03 | 1985-08-02 | AMINOANTHRACENDION PLATIN COMPLEXES USEFUL AS ANTICANCER RELATIONSHIPS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21324/85A IT1201425B (en) | 1985-06-27 | 1985-06-27 | New platinum 1,4-di:amino-anthraquinone complexes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8521324A0 IT8521324A0 (en) | 1985-06-27 |
| IT1201425B true IT1201425B (en) | 1989-02-02 |
Family
ID=11180121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT21324/85A IT1201425B (en) | 1984-08-03 | 1985-06-27 | New platinum 1,4-di:amino-anthraquinone complexes |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1201425B (en) |
-
1985
- 1985-06-27 IT IT21324/85A patent/IT1201425B/en active
Also Published As
| Publication number | Publication date |
|---|---|
| IT8521324A0 (en) | 1985-06-27 |
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