IT1197482B - EDTA-free heparin in prods. - Google Patents
EDTA-free heparin in prods.Info
- Publication number
- IT1197482B IT1197482B IT21901/86A IT2190186A IT1197482B IT 1197482 B IT1197482 B IT 1197482B IT 21901/86 A IT21901/86 A IT 21901/86A IT 2190186 A IT2190186 A IT 2190186A IT 1197482 B IT1197482 B IT 1197482B
- Authority
- IT
- Italy
- Prior art keywords
- edta
- prods
- free heparin
- heparin
- free
- Prior art date
Links
- 229960002897 heparin Drugs 0.000 title abstract 2
- 229920000669 heparin Polymers 0.000 title abstract 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract 2
- 238000005160 1H NMR spectroscopy Methods 0.000 abstract 1
- 239000002565 heparin fraction Substances 0.000 abstract 1
- 239000002634 heparin fragment Substances 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
Landscapes
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Heparins and heparin fractions or fragments, opt. in salt form, with a molecular wt. of 1000-30,000, with an EDTA content of less than 0.1% and no EDTA signals between 2.50 and 4.00 ppm in their 'H-NMR spectra, are new.
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21901/86A IT1197482B (en) | 1986-10-03 | 1986-10-03 | EDTA-free heparin in prods. |
| EP87106784A EP0245813B2 (en) | 1986-05-16 | 1987-05-11 | EDTA-free heparins, heparin fractions and fragments, processes for their preparation and pharmaceutical compositions containing them |
| ES87106784T ES2059321T3 (en) | 1986-05-16 | 1987-05-11 | HEPARINES, FRACTIONS AND FRAGMENTS OF EDTA-FREE HEPARINES, PROCEDURE FOR THE PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM. |
| DE87106784T DE3787996T2 (en) | 1986-05-16 | 1987-05-11 | Heparin free from E.D.T.A., fractions and fragments of heparin, processes for their preparation and pharmaceutical compositions containing them. |
| AT87106784T ATE96809T1 (en) | 1986-05-16 | 1987-05-11 | E.D.T.A.-FREE HEPARINS, FRACTIONS AND FRAGMENTS OF HEPARIN, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| JP62118692A JP2628507B2 (en) | 1986-05-16 | 1987-05-15 | EDTA-free heparin, heparin fractions and fragments, processes for their preparation and pharmaceutical compositions containing them |
| US07/587,605 US5110918A (en) | 1986-05-16 | 1990-09-24 | Process for preparing EDTA-free heparins, heparin fractions and fragments |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21901/86A IT1197482B (en) | 1986-10-03 | 1986-10-03 | EDTA-free heparin in prods. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8621901A0 IT8621901A0 (en) | 1986-10-03 |
| IT1197482B true IT1197482B (en) | 1988-11-30 |
Family
ID=11188461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT21901/86A IT1197482B (en) | 1986-05-16 | 1986-10-03 | EDTA-free heparin in prods. |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1197482B (en) |
-
1986
- 1986-10-03 IT IT21901/86A patent/IT1197482B/en active
Also Published As
| Publication number | Publication date |
|---|---|
| IT8621901A0 (en) | 1986-10-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971029 |