IT1194372B - PROCEDURE FOR THE PREPARATION OF 2,4-DIAMINE-5-BENZYL-PYRIMIDINE DERIVATIVES - Google Patents

PROCEDURE FOR THE PREPARATION OF 2,4-DIAMINE-5-BENZYL-PYRIMIDINE DERIVATIVES

Info

Publication number
IT1194372B
IT1194372B IT22540/83A IT2254083A IT1194372B IT 1194372 B IT1194372 B IT 1194372B IT 22540/83 A IT22540/83 A IT 22540/83A IT 2254083 A IT2254083 A IT 2254083A IT 1194372 B IT1194372 B IT 1194372B
Authority
IT
Italy
Prior art keywords
diamine
benzyl
procedure
preparation
pyrimidine derivatives
Prior art date
Application number
IT22540/83A
Other languages
Italian (it)
Other versions
IT8322540A1 (en
IT8322540A0 (en
Inventor
Ivan Peck
Janos Egri
Elemer Jakfalvi
Gyorgyi Kovanyi
Eva Furdyga
Istvan Simonyi
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of IT8322540A0 publication Critical patent/IT8322540A0/en
Publication of IT8322540A1 publication Critical patent/IT8322540A1/en
Application granted granted Critical
Publication of IT1194372B publication Critical patent/IT1194372B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/12—Saturated ethers containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Liquid Crystal Substances (AREA)
IT22540/83A 1982-08-13 1983-08-12 PROCEDURE FOR THE PREPARATION OF 2,4-DIAMINE-5-BENZYL-PYRIMIDINE DERIVATIVES IT1194372B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU822604A HU188588B (en) 1982-08-13 1982-08-13 Process for the production of 2,4-diamino-5-benzyl-pyrimidine-derivatives

Publications (3)

Publication Number Publication Date
IT8322540A0 IT8322540A0 (en) 1983-08-12
IT8322540A1 IT8322540A1 (en) 1985-02-12
IT1194372B true IT1194372B (en) 1988-09-22

Family

ID=10960229

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22540/83A IT1194372B (en) 1982-08-13 1983-08-12 PROCEDURE FOR THE PREPARATION OF 2,4-DIAMINE-5-BENZYL-PYRIMIDINE DERIVATIVES

Country Status (8)

Country Link
JP (1) JPS5993061A (en)
AT (1) AT387216B (en)
CH (1) CH657611A5 (en)
DE (1) DE3329226A1 (en)
GB (1) GB2125044B (en)
HU (1) HU188588B (en)
IT (1) IT1194372B (en)
SU (1) SU1222194A3 (en)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR94837E (en) * 1966-02-19 1969-11-28 Wellcome Found Process for the preparation of pyrimidine derivatives.
CH598231A5 (en) * 1973-07-27 1978-04-28 Hoffmann La Roche
DK136470B (en) * 1973-11-08 1977-10-17 Hoffmann La Roche Analogous process for the preparation of 2,4-diamino-5-benzylpyrimidine derivatives or salts thereof.
AR207671A1 (en) * 1975-01-03 1976-10-22 Prayon PROCEDURE FOR OBTAINING A BASIC PIGMENT OF IRON OXIDE IN ALPHA-FE2O3 FORM
DE2559752C3 (en) * 1975-10-17 1978-12-07 Ludwig Heumann & Co Gmbh, 8500 Nuernberg 2,4-diamino-5- (3-methoxy-4-hydroxy-5-methyl-benzyl) -pyrimidine, process for its preparation and medicament containing this compound
DE2546667C3 (en) * 1975-10-17 1978-10-12 Ludwig Heumann & Co Gmbh, 8500 Nuernberg 2,4-DiamuH »-5- (3-methoxy-4-hydroxy-5-halobenzyl) -pyrimidines, and medicinal products containing these compounds
DE2617967C3 (en) * 1976-04-24 1978-11-02 Nordmark-Werke Gmbh, 2000 Hamburg Process for the preparation of 2,4-diamino-5-benzylpyrimidines
DE2635765C3 (en) * 1976-08-09 1979-02-08 Ludwig Heumann & Co Gmbh, 8500 Nuernberg Process for the preparation of 2,4-EMamino-5- (3 ', 4'r5'-trimethoxybenzyl) -pyrimidine
PT69656A (en) * 1978-05-24 1979-06-01 Wellcome Found Benzylpyrimidine compositions

Also Published As

Publication number Publication date
IT8322540A1 (en) 1985-02-12
DE3329226A1 (en) 1984-02-23
HU188588B (en) 1986-04-28
GB8321618D0 (en) 1983-09-14
AT387216B (en) 1988-12-27
CH657611A5 (en) 1986-09-15
JPS5993061A (en) 1984-05-29
ATA290583A (en) 1988-05-15
SU1222194A3 (en) 1986-03-30
GB2125044A (en) 1984-02-29
IT8322540A0 (en) 1983-08-12
GB2125044B (en) 1985-09-18

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