IT1178041B - New hyaluronic acid fractions - Google Patents
New hyaluronic acid fractionsInfo
- Publication number
- IT1178041B IT1178041B IT48979/84A IT4897984A IT1178041B IT 1178041 B IT1178041 B IT 1178041B IT 48979/84 A IT48979/84 A IT 48979/84A IT 4897984 A IT4897984 A IT 4897984A IT 1178041 B IT1178041 B IT 1178041B
- Authority
- IT
- Italy
- Prior art keywords
- hyaluronic acid
- acid fractions
- new
- new hyaluronic
- fractions
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 2
- 239000000061 acid fraction Substances 0.000 title abstract 2
- 229920002674 hyaluronan Polymers 0.000 title abstract 2
- 229960003160 hyaluronic acid Drugs 0.000 title abstract 2
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Pure non-inflammatory hyaluronic acid fractions (I) with an av. molecular wt. of 30,000-730,000 and their Na and K salts are new. The fractions have molecular wts. of 50,000-100,000 (Ia), 250,000-350,000 (Ib) and 500,000-730,000 (Ic).
Priority Applications (29)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT48979/84A IT1178041B (en) | 1984-10-09 | 1984-10-09 | New hyaluronic acid fractions |
| FR848415547A FR2553099B1 (en) | 1983-10-11 | 1984-10-10 | HYALURONIC ACID FRACTIONS HAVING PHARMACEUTICAL ACTIVITY, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| NO844054A NO169637C (en) | 1983-10-11 | 1984-10-10 | PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE HYALURONIC ACID FRACTIONS |
| IN711/CAL/84A IN163192B (en) | 1983-10-11 | 1984-10-10 | |
| DK485384A DK171029B1 (en) | 1983-10-11 | 1984-10-10 | Hyaluronic Acid Fraction, Process for Preparation thereof, and Ophthalmic Preparations Containing Hyaluronic Acid Fraction |
| LU85582A LU85582A1 (en) | 1983-10-11 | 1984-10-10 | HYALURONIC ACID FRACTIONS HAVING PHARMACEUTICAL ACTIVITY, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| DE8484306914T DE3482812D1 (en) | 1983-10-11 | 1984-10-10 | FRACTIONS OF HYALURONIC ACID WITH PHARMACEUTICAL ACTIVITY, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME. |
| AT84306914T ATE54921T1 (en) | 1983-10-11 | 1984-10-10 | HYALURONIC ACID FRACTIONS WITH PHARMACEUTICAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| IL96943A IL96943A (en) | 1984-10-09 | 1984-10-10 | Pharmaceutical compositions for ophthalmic administration comprising a combination of hyaluronic acid fractions and ophthalmic drugs |
| EP84306914A EP0138572B1 (en) | 1983-10-11 | 1984-10-10 | Hyaluronic acid fractions having pharmaceutical activity, methods for preparation thereof, and pharmaceutical compositions containing the same |
| IE2596/84A IE57931B1 (en) | 1983-10-11 | 1984-10-10 | Hyaluronic acid fractions having pharmaceutical activity,methods for preparation thereof,and pharmaceutical compositions containing the same |
| CH4866/84A CH666897A5 (en) | 1983-10-11 | 1984-10-10 | NON-INFLAMMATORY HYALURONIC ACID FRACTIONS, PHARMACEUTICAL METHODS AND COMPOSITIONS. |
| CA000465231A CA1205031A (en) | 1983-10-11 | 1984-10-11 | Hyaluronic acid fractions having pharmaceutical activity, and processes for the preparation thereof |
| ES536675A ES8507573A1 (en) | 1983-10-11 | 1984-10-11 | Hyaluronic acid fractions having pharmaceutical activity, methods for preparation thereof, and pharmaceutical compositions containing the same. |
| BE0/213822A BE900810A (en) | 1983-10-11 | 1984-10-11 | FRACTIONS D'ACIDE HYALURONIQUE AYANT UNE ACTIVITE PHARMACEUTIQUE, PROCEDES POUR LEUR PREPARATION ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT. |
| NZ209850A NZ209850A (en) | 1984-10-09 | 1984-10-11 | Preparing pure hyaluronic acid fractions and pharmaceutical compositions |
| FI843990A FI79554C (en) | 1983-10-11 | 1984-10-11 | FOERFARANDE FOER FRAMSTAELLNING AV HYALURONSYRAFRAKTIONER MED FARMACEUTISK AKTIVITET. |
| AU34148/84A AU575861B2 (en) | 1983-10-11 | 1984-10-11 | Compositions and extraction of hyaluronic acid |
| HU843811A HU195523B (en) | 1983-10-11 | 1984-10-11 | Process for producing fractions of hyaluronic acid and pharmaceutical compositions containing them |
| AR298247A AR231992A1 (en) | 1983-10-11 | 1984-10-11 | PROCEDURE FOR THE MANUFACTURE OF HYALURONIC ACID FRACTIONS |
| PT79339A PT79339B (en) | 1983-10-11 | 1984-10-11 | Process for the preparation of hyaluronic acid fractions with pharmaceutical activity |
| KR1019840006280A KR860001148B1 (en) | 1983-10-11 | 1984-10-11 | Method for preparing hyaluronic acid with pharmacological action |
| PH32103A PH23149A (en) | 1984-10-09 | 1985-04-08 | Hyaluronic acid fractions having pharmaceutical activity,pharmaceutical compositions containing the same and method of use thereof |
| US07/452,681 US5166331A (en) | 1983-10-10 | 1989-12-19 | Hyaluronics acid fractions, methods for the preparation thereof, and pharmaceutical compositions containing same |
| IL96943A IL96943A0 (en) | 1984-10-09 | 1991-01-14 | Pharmaceutical compositions for ophthalmic administration comprising a combination of hyaluronic acid fractions and ophthalmic drugs |
| SG594/91A SG59491G (en) | 1983-10-11 | 1991-07-25 | Hyaluronic acid fractions having pharmaceutical activity,methods for preparation thereof,and pharmaceutical compositions containing the same |
| HK660/91A HK66091A (en) | 1983-10-11 | 1991-08-22 | Hyaluronic acid fractions having pharmaceutical activity, methods for preparation thereof, and pharmaceutical compositions containing the same |
| US07/931,949 US5442053A (en) | 1982-09-28 | 1992-08-19 | Salts and mixtures of hyaluronic acid with pharmaceutically active substances, pharmaceutical compositions containing the same and methods for administration of such compositions |
| US08/426,905 US5631241A (en) | 1983-10-10 | 1995-04-21 | Pharmaceutical compositions containing hyaluronic acid fractions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT48979/84A IT1178041B (en) | 1984-10-09 | 1984-10-09 | New hyaluronic acid fractions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT8448979A0 IT8448979A0 (en) | 1984-10-09 |
| IT8448979A1 IT8448979A1 (en) | 1986-04-09 |
| IT1178041B true IT1178041B (en) | 1987-09-03 |
Family
ID=11269258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT48979/84A IT1178041B (en) | 1982-09-28 | 1984-10-09 | New hyaluronic acid fractions |
Country Status (3)
| Country | Link |
|---|---|
| IT (1) | IT1178041B (en) |
| NZ (1) | NZ209850A (en) |
| PH (1) | PH23149A (en) |
-
1984
- 1984-10-09 IT IT48979/84A patent/IT1178041B/en active
- 1984-10-11 NZ NZ209850A patent/NZ209850A/en unknown
-
1985
- 1985-04-08 PH PH32103A patent/PH23149A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ209850A (en) | 1987-11-27 |
| IT8448979A1 (en) | 1986-04-09 |
| PH23149A (en) | 1989-05-11 |
| IT8448979A0 (en) | 1984-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19981002 |