IT1166592B - Redn. of blood lipid levels in animals - by admin. of 2-alkyl-3-amino-4-carboxy-thiophene deriv. - Google Patents

Redn. of blood lipid levels in animals - by admin. of 2-alkyl-3-amino-4-carboxy-thiophene deriv.

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Publication number
IT1166592B
IT1166592B IT1956979A IT1956979A IT1166592B IT 1166592 B IT1166592 B IT 1166592B IT 1956979 A IT1956979 A IT 1956979A IT 1956979 A IT1956979 A IT 1956979A IT 1166592 B IT1166592 B IT 1166592B
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IT
Italy
Prior art keywords
alkyl
redn
admin
blood lipid
deriv
Prior art date
Application number
IT1956979A
Other languages
Italian (it)
Other versions
IT7919569A0 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IT7919569A0 publication Critical patent/IT7919569A0/en
Application granted granted Critical
Publication of IT1166592B publication Critical patent/IT1166592B/en

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Abstract

The redn. is effected by admin. of a cpd. of formula (I) or its salts. (R is 1-8C alkyl; R2 is H, OH, 1-8C alkoxy or NH2; and R3 and R4 are 1-8C alkyl, aryl, aralkyl or H). (I) are blood lipid lowering and antiobesity agents, and so they are useful for the treatment of atherosclerosis and related cardiovascular diseases. They selectively reduce body fat by inhibiting its biosynthesis. The cpds. are described in U.S. 4317915 (22048 E/11). The cpd. in which R and R2 are Me and R3 and R4 are H is pref. used.
IT1956979A 1978-03-23 1979-01-24 Redn. of blood lipid levels in animals - by admin. of 2-alkyl-3-amino-4-carboxy-thiophene deriv. IT1166592B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88945978A 1978-03-23 1978-03-23

Publications (2)

Publication Number Publication Date
IT7919569A0 IT7919569A0 (en) 1979-01-24
IT1166592B true IT1166592B (en) 1987-05-05

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Family Applications (1)

Application Number Title Priority Date Filing Date
IT1956979A IT1166592B (en) 1978-03-23 1979-01-24 Redn. of blood lipid levels in animals - by admin. of 2-alkyl-3-amino-4-carboxy-thiophene deriv.

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Country Link
IT (1) IT1166592B (en)

Also Published As

Publication number Publication date
IT7919569A0 (en) 1979-01-24

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