IT1143012B - PYRIMIDINIC 6-ARIL COMPOUNDS FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS AND TO STIMULATE THE PRODUCTION OF INTERFERONE - Google Patents

PYRIMIDINIC 6-ARIL COMPOUNDS FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS AND TO STIMULATE THE PRODUCTION OF INTERFERONE

Info

Publication number
IT1143012B
IT1143012B IT48119/80A IT4811980A IT1143012B IT 1143012 B IT1143012 B IT 1143012B IT 48119/80 A IT48119/80 A IT 48119/80A IT 4811980 A IT4811980 A IT 4811980A IT 1143012 B IT1143012 B IT 1143012B
Authority
IT
Italy
Prior art keywords
pyrimidinic
interferone
aril
stimulate
prevention
Prior art date
Application number
IT48119/80A
Other languages
Italian (it)
Other versions
IT8048119A0 (en
Inventor
Wendell Wierenga
Harvey Irving Skulnich
Dale Alan Stringfellow
Patricia Evelyn Fast
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of IT8048119A0 publication Critical patent/IT8048119A0/en
Application granted granted Critical
Publication of IT1143012B publication Critical patent/IT1143012B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT48119/80A 1979-03-19 1980-03-10 PYRIMIDINIC 6-ARIL COMPOUNDS FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS AND TO STIMULATE THE PRODUCTION OF INTERFERONE IT1143012B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2220579A 1979-03-19 1979-03-19
US7985079A 1979-09-28 1979-09-28

Publications (2)

Publication Number Publication Date
IT8048119A0 IT8048119A0 (en) 1980-03-10
IT1143012B true IT1143012B (en) 1986-10-22

Family

ID=26695670

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48119/80A IT1143012B (en) 1979-03-19 1980-03-10 PYRIMIDINIC 6-ARIL COMPOUNDS FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS AND TO STIMULATE THE PRODUCTION OF INTERFERONE

Country Status (7)

Country Link
JP (1) JPH0627070B2 (en)
CH (1) CH646958A5 (en)
DE (1) DE3008693A1 (en)
FR (1) FR2451918A1 (en)
GB (1) GB2048250B (en)
IT (1) IT1143012B (en)
NL (1) NL8001568A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0111440A1 (en) * 1982-10-15 1984-06-20 Ciba-Geigy Ag 2-Aminopyrimidines, their production and use
US4795812A (en) * 1985-02-05 1989-01-03 The Upjohn Company 4-substituted-6-aryl-pyrimidine compounds
GB9012311D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
AU5687198A (en) * 1996-12-12 1998-07-03 Pharmacia & Upjohn Company Method for treating multiple sclerosis
CA2359680A1 (en) * 1999-01-22 2000-07-27 David M. Armistead Kinase inhibitors
US6495558B1 (en) 1999-01-22 2002-12-17 Amgen Inc. Kinase inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2688019A (en) * 1951-08-25 1954-08-31 Burroughs Wellcome Co 6-aryl-2,4-diamino pyrimidines and process of preparing same
US2723977A (en) * 1953-07-29 1955-11-15 Searle & Co 5, 6-disubstituted 2-amino-4-pyrimidols
US2723978A (en) * 1954-01-14 1955-11-15 Searle & Co 2-amino-5-alkenyl-6-phenyl-4-pyrimidols
US2710867A (en) * 1954-03-12 1955-06-14 Searle & Co New 2-amino-4-pyrimidol derivatives
US2704285A (en) * 1954-06-17 1955-03-15 Searle & Co 2-amino-5-(lower alkyl)-6-substituted phenyl-4-pyrimidols
US2748121A (en) * 1954-06-17 1956-05-29 Searle & Co 6-nitroaryl derivatives of 2-amino-4-pyrimidols
US3281420A (en) * 1966-01-27 1966-10-25 Searle & Co Carboxylic acid [2-(2-amino-4-azido-6-phenyl-5-pyrimidinyl)-1-methylethylidene] hydrazides and intermediate
US3412094A (en) * 1967-06-21 1968-11-19 Searle & Co 5-alkyl-2-amino-4-azido-6-phenylpyrimidines and congeners
US3932617A (en) * 1974-05-24 1976-01-13 The Upjohn Company Interferon induction

Also Published As

Publication number Publication date
GB2048250A (en) 1980-12-10
NL8001568A (en) 1980-09-23
GB2048250B (en) 1983-04-27
CH646958A5 (en) 1984-12-28
DE3008693A1 (en) 1980-10-02
JPH0517451A (en) 1993-01-26
IT8048119A0 (en) 1980-03-10
JPH0627070B2 (en) 1994-04-13
FR2451918B1 (en) 1984-01-06
FR2451918A1 (en) 1980-10-17

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19990331