IT1140776B - 24,24-DIFLUORO-1, ALPHA, 25-DIHYDROXYCOLCIFEROL - Google Patents
24,24-DIFLUORO-1, ALPHA, 25-DIHYDROXYCOLCIFEROLInfo
- Publication number
- IT1140776B IT1140776B IT20508/80A IT2050880A IT1140776B IT 1140776 B IT1140776 B IT 1140776B IT 20508/80 A IT20508/80 A IT 20508/80A IT 2050880 A IT2050880 A IT 2050880A IT 1140776 B IT1140776 B IT 1140776B
- Authority
- IT
- Italy
- Prior art keywords
- dihydroxycolciferol
- difluoro
- alpha
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/48—Halogenated derivatives
- C07C35/52—Alcohols with a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nutrition Science (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/024,848 US4201881A (en) | 1979-03-28 | 1979-03-28 | 24,24-Difluoro-1α,25-dihydroxycholecalciferol |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8020508A0 IT8020508A0 (en) | 1980-03-11 |
IT1140776B true IT1140776B (en) | 1986-10-10 |
Family
ID=21822707
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT20508/80A IT1140776B (en) | 1979-03-28 | 1980-03-11 | 24,24-DIFLUORO-1, ALPHA, 25-DIHYDROXYCOLCIFEROL |
Country Status (15)
Country | Link |
---|---|
US (1) | US4201881A (en) |
JP (2) | JPS6342618B2 (en) |
AU (1) | AU530015B2 (en) |
BE (1) | BE882143A (en) |
CH (1) | CH650240A5 (en) |
DK (1) | DK147300C (en) |
FR (1) | FR2452481A1 (en) |
GB (2) | GB2067567B (en) |
IE (1) | IE49753B1 (en) |
IL (1) | IL58526A (en) |
IT (1) | IT1140776B (en) |
NL (1) | NL7920190A (en) |
NZ (1) | NZ191900A (en) |
SE (1) | SE8008339L (en) |
WO (1) | WO1980002028A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4284577A (en) * | 1979-02-16 | 1981-08-18 | Sachiko Yamada | Novel vitamin D3 derivative and process for preparing the same |
EP0073465B1 (en) * | 1981-08-28 | 1986-02-05 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Cholecalciferol derivatives |
NZ204223A (en) * | 1982-05-17 | 1986-11-12 | Hoffmann La Roche | Veterinary compositions containing 24,24-difluoro-1 alpha,25-dihydroxycholecalciferol |
US4456689A (en) * | 1982-05-17 | 1984-06-26 | Becton Dickinson And Company | Competitive protein binding assay using an organosilane-silica gel separation medium |
US4428946A (en) * | 1982-07-26 | 1984-01-31 | Wisconsin Alumni Research Foundation | Method of preventing milk fever in dairy cattle |
EP0205285B1 (en) * | 1985-05-30 | 1989-08-09 | Taisho Pharmaceutical Co. Ltd | Vitamin d3 derivatives |
EP0245524B1 (en) * | 1985-11-21 | 1991-04-17 | Taisho Pharmaceutical Co. Ltd | Vitamin d 3 derivative |
US4853378A (en) * | 1986-10-20 | 1989-08-01 | Sumitomo Chemical Company, Limited | Fluorine derivatives of vitamin D3 and process for producing the same |
AU5185790A (en) * | 1989-02-16 | 1990-09-05 | University Of Georgia Research Foundation, Inc., The | Treatment of tibial dyschondroplasia |
US5316770A (en) * | 1989-02-16 | 1994-05-31 | University Of Georgia Research Foundation, Inc. | Vitamin D derivative feed compositions and methods of use |
US5366736A (en) * | 1989-02-16 | 1994-11-22 | University Of Georgia Research Foundation, Inc. | Vitamin D derivative feed compositions and methods of use |
US5063234A (en) * | 1990-05-25 | 1991-11-05 | Eli Lilly And Company | Method of inhibiting demineralization of bone |
US7718637B2 (en) * | 2007-12-28 | 2010-05-18 | Wisconsin Alumni Research Foundation | (20S)-23,23-difluoro-methylene-19-nor-bishomopregnacalciferol-vitamin D analogs |
JP5504898B2 (en) * | 2010-01-08 | 2014-05-28 | セントラル硝子株式会社 | Method for producing difluorocyclopropane compound |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3741996A (en) * | 1971-12-02 | 1973-06-26 | Wisconsin Alumni Res Found | 1{60 -hydroxycholecalciferol |
US3969700A (en) * | 1974-04-10 | 1976-07-13 | International Business Machines Corporation | Regional context maximum likelihood error correction for OCR, keyboard, and the like |
FR2267590B1 (en) * | 1974-04-10 | 1977-05-20 | Ibm | |
JPS5729745B2 (en) * | 1974-09-25 | 1982-06-24 | ||
US3993675A (en) * | 1975-02-24 | 1976-11-23 | Hoffmann-La Roche Inc. | Process for the preparation of 1α,25-dihydroxycholecalciferol |
US4069321A (en) * | 1975-10-14 | 1978-01-17 | Merck & Co., Inc. | Blocked cholecalciferol and dihydrotachysterol 3 derivatives |
US4284577A (en) * | 1979-02-16 | 1981-08-18 | Sachiko Yamada | Novel vitamin D3 derivative and process for preparing the same |
-
1979
- 1979-03-28 US US06/024,848 patent/US4201881A/en not_active Expired - Lifetime
- 1979-10-15 JP JP55500243A patent/JPS6342618B2/ja not_active Expired
- 1979-10-15 NL NL7920190A patent/NL7920190A/en unknown
- 1979-10-15 CH CH8817/80A patent/CH650240A5/en not_active IP Right Cessation
- 1979-10-15 WO PCT/US1979/000899 patent/WO1980002028A1/en unknown
- 1979-10-22 IL IL58526A patent/IL58526A/en unknown
-
1980
- 1980-02-08 NZ NZ191900A patent/NZ191900A/en unknown
- 1980-02-22 AU AU55810/80A patent/AU530015B2/en not_active Ceased
- 1980-03-07 BE BE0/199728A patent/BE882143A/en not_active IP Right Cessation
- 1980-03-11 IT IT20508/80A patent/IT1140776B/en active
- 1980-03-13 GB GB8035585A patent/GB2067567B/en not_active Expired
- 1980-03-13 GB GB8008488A patent/GB2045765B/en not_active Expired
- 1980-03-17 FR FR8005935A patent/FR2452481A1/en active Granted
- 1980-03-26 IE IE619/80A patent/IE49753B1/en unknown
- 1980-11-27 DK DK505080A patent/DK147300C/en not_active IP Right Cessation
- 1980-11-27 SE SE8008339A patent/SE8008339L/en unknown
-
1987
- 1987-09-16 JP JP62229955A patent/JPS63179855A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
IL58526A0 (en) | 1980-01-31 |
GB2067567A (en) | 1981-07-30 |
SE8008339L (en) | 1980-11-27 |
AU5581080A (en) | 1980-10-02 |
IE49753B1 (en) | 1985-12-11 |
US4201881A (en) | 1980-05-06 |
GB2045765B (en) | 1983-06-15 |
BE882143A (en) | 1980-07-01 |
GB2045765A (en) | 1980-11-05 |
NZ191900A (en) | 1984-11-09 |
DK147300C (en) | 1984-12-24 |
FR2452481B1 (en) | 1984-10-19 |
GB2067567B (en) | 1983-03-02 |
IL58526A (en) | 1983-05-15 |
WO1980002028A1 (en) | 1980-10-02 |
NL7920190A (en) | 1981-01-30 |
DK505080A (en) | 1980-11-27 |
JPS56500296A (en) | 1981-03-12 |
DK147300B (en) | 1984-06-12 |
CH650240A5 (en) | 1985-07-15 |
IT8020508A0 (en) | 1980-03-11 |
JPS63179855A (en) | 1988-07-23 |
AU530015B2 (en) | 1983-06-30 |
JPS6342618B2 (en) | 1988-08-24 |
JPH0146504B2 (en) | 1989-10-09 |
FR2452481A1 (en) | 1980-10-24 |
IE800619L (en) | 1980-09-28 |
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