IT1107793B - Procedimento per la preparazione di antibiotici del gruppo delle cefalo sportine e prodotto ottenuto - Google Patents

Procedimento per la preparazione di antibiotici del gruppo delle cefalo sportine e prodotto ottenuto

Info

Publication number
IT1107793B
IT1107793B IT52060/78A IT5206078A IT1107793B IT 1107793 B IT1107793 B IT 1107793B IT 52060/78 A IT52060/78 A IT 52060/78A IT 5206078 A IT5206078 A IT 5206078A IT 1107793 B IT1107793 B IT 1107793B
Authority
IT
Italy
Prior art keywords
sportine
cefalo
antibiotics
procedure
preparation
Prior art date
Application number
IT52060/78A
Other languages
English (en)
Other versions
IT7852060A0 (it
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT7852060A0 publication Critical patent/IT7852060A0/it
Application granted granted Critical
Publication of IT1107793B publication Critical patent/IT1107793B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
IT52060/78A 1977-11-25 1978-11-24 Procedimento per la preparazione di antibiotici del gruppo delle cefalo sportine e prodotto ottenuto IT1107793B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/854,457 US4118563A (en) 1977-11-25 1977-11-25 Production of 7-(2-aminomethylphenylacetamido-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid

Publications (2)

Publication Number Publication Date
IT7852060A0 IT7852060A0 (it) 1978-11-24
IT1107793B true IT1107793B (it) 1985-11-25

Family

ID=25318746

Family Applications (1)

Application Number Title Priority Date Filing Date
IT52060/78A IT1107793B (it) 1977-11-25 1978-11-24 Procedimento per la preparazione di antibiotici del gruppo delle cefalo sportine e prodotto ottenuto

Country Status (6)

Country Link
US (1) US4118563A (it)
JP (2) JPS5476594A (it)
CA (1) CA1109462A (it)
ES (1) ES475396A1 (it)
FR (2) FR2424923A1 (it)
IT (1) IT1107793B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4297489A (en) * 1974-09-03 1981-10-27 Bristol-Myers Company 7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids
US4220644A (en) * 1976-05-03 1980-09-02 Smithkline Corporation 7-Acylamino-3-(substituted tetrazolyl thiomethyl) cephalosporins
US4243803A (en) * 1979-07-05 1981-01-06 Bristol-Myers Company Production of 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
JPH02193638A (ja) * 1989-01-23 1990-07-31 Kowa Co 眼科測定装置
WO2008010043A2 (en) * 2006-07-18 2008-01-24 Orchid Chemicals & Pharmaceuticals Limited Improved process for the preparation of ceforanide in pure form

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1057029A (en) * 1962-10-24 1967-02-01 Distillers Co Yeast Ltd New penicillins
US3382241A (en) * 1967-02-27 1968-05-07 Lilly Co Eli Certain orally active cephalosporin antibiotics
DK130742B (da) * 1970-03-13 1975-04-07 Molecular R & L Research Ltd Analogifremgangsmåde til fremstilling af 7-[(aminomethylphenylthio)-acetamido]cephalosporansyrederivater.
US3663540A (en) * 1970-06-19 1972-05-16 R & L Molecular Research Ltd 7 - (p-aminomethylphenylthio)acetamido-3 -(pyridiniummethyl)ceph - 3 - em - 4-carboxylate
US3657232A (en) * 1970-06-19 1972-04-18 R & L Molecular Research Ltd 7-((o-aminomethylphenylthio)-acetamido) cephalosporanic acid
US3766175A (en) * 1971-05-11 1973-10-16 R & L Molecular Research Ltd Certain 7 - (o-aminomethylphenylacetamido) - 3-((heterocyclylthio)methyl)ceph-3-em-4-carboxylic acids
BE790093A (fr) * 1971-10-14 1973-04-13 R & L Procede pour preparer des agents antibacteriens
US3840535A (en) * 1972-08-23 1974-10-08 Bristol Myers Co Dimethanesulfonates of certain 7-(o-aminomethylphenylacetamido)-3-((heterocyclylthio)methyl)-ceph-3-em-4-carboxylic acids
US3813391A (en) * 1972-09-06 1974-05-28 Bristol Myers Co 7-(beta-(o-aminomethylphenyl)propion-amido)-3-(tetrazolo(4,5-b)pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
US3814755A (en) * 1972-08-30 1974-06-04 Bristol Myers Co 7-(omikron-aminomethylphenylacetamido)-3-(tetrazolo(4,5-b)pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
US3823141A (en) * 1972-09-06 1974-07-09 Bristol Myers Co 7-(o-aminomethyl-p-hydroxy-phenylacetamido)-3-(3-hydroxy-pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
US3813376A (en) * 1972-08-31 1974-05-28 Bristol Myers Co 7-(o-aminomethylphenyl-acetamido)-3-(3-hydroxypyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
US3946000A (en) * 1973-10-31 1976-03-23 Bristol-Myers Company 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids
US3907786A (en) * 1973-09-04 1975-09-23 Bristol Myers Co 7-{8 {60 -(2-aminomethyl-1,4-cyclohexadienyl)acetamido{9 -3-heterocyclic-thiomethyl-3-cephem-4-carboxylic acids and salts
US3910899A (en) * 1973-09-07 1975-10-07 Bristol Myers Co 7-(2-Aminomethylphenyl-acetamido)-3-{8 2-(5-hydroxymethyl-1,3,4-thiadiazolyl)-thiomethyl{9 -3-cephem-4-carboxylic acid
US3966710A (en) * 1974-11-12 1976-06-29 Pfizer Inc. Aminomethylarylmethylpenicillin derivatives
US4045438A (en) * 1975-10-24 1977-08-30 Yeda Research And Development Co. Ltd. Cephalosporin antibiotics

Also Published As

Publication number Publication date
CA1109462A (en) 1981-09-22
IT7852060A0 (it) 1978-11-24
JPS6338355B2 (it) 1988-07-29
US4118563A (en) 1978-10-03
ES475396A1 (es) 1980-01-16
FR2424923A1 (fr) 1979-11-30
JPS5476594A (en) 1979-06-19
FR2416896A1 (fr) 1979-09-07
JPS62174082A (ja) 1987-07-30
JPH0251557B2 (it) 1990-11-07
FR2424923B1 (it) 1983-04-29
FR2416896B1 (it) 1983-04-15

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971129