IT1106666B - DERIVATIVES OF BENZOYLPHENOXYL ALCHYL ACIDS WITH NORMOLIPEMIZING ACTION - Google Patents

DERIVATIVES OF BENZOYLPHENOXYL ALCHYL ACIDS WITH NORMOLIPEMIZING ACTION

Info

Publication number
IT1106666B
IT1106666B IT03426/78A IT342678A IT1106666B IT 1106666 B IT1106666 B IT 1106666B IT 03426/78 A IT03426/78 A IT 03426/78A IT 342678 A IT342678 A IT 342678A IT 1106666 B IT1106666 B IT 1106666B
Authority
IT
Italy
Prior art keywords
normolipemizing
benzoylphenoxyl
alchyl
derivatives
acids
Prior art date
Application number
IT03426/78A
Other languages
Italian (it)
Other versions
IT7803426A0 (en
Inventor
Valerio Borzatta
Cristofori Manlio
Mauro Morotti
Giuseppe Mascellani
Original Assignee
Alfa Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa
Publication of IT7803426A0 publication Critical patent/IT7803426A0/en
Priority to IT03426/78A priority Critical patent/IT1106666B/en
Priority to NL7903434A priority patent/NL7903434A/en
Priority to GR59030A priority patent/GR72241B/el
Priority to ES480329A priority patent/ES480329A1/en
Priority to YU01077/79A priority patent/YU107779A/en
Priority to BE2/57777A priority patent/BE876094A/en
Priority to JP5623479A priority patent/JPS54163560A/en
Priority to NO791532A priority patent/NO791532L/en
Priority to FR7911587A priority patent/FR2425425A1/en
Priority to DK189479A priority patent/DK189479A/en
Priority to AT0343279A priority patent/AT367016B/en
Priority to SE7903982A priority patent/SE7903982L/en
Priority to DE19792918748 priority patent/DE2918748A1/en
Priority to GB7916093A priority patent/GB2025394B/en
Priority to US06/123,454 priority patent/US4296125A/en
Priority to US06/255,430 priority patent/US4378373A/en
Priority to US06/255,431 priority patent/US4515809A/en
Application granted granted Critical
Publication of IT1106666B publication Critical patent/IT1106666B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT03426/78A 1978-05-09 1978-05-09 DERIVATIVES OF BENZOYLPHENOXYL ALCHYL ACIDS WITH NORMOLIPEMIZING ACTION IT1106666B (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
IT03426/78A IT1106666B (en) 1978-05-09 1978-05-09 DERIVATIVES OF BENZOYLPHENOXYL ALCHYL ACIDS WITH NORMOLIPEMIZING ACTION
NL7903434A NL7903434A (en) 1978-05-09 1979-05-02 DERIVATIVES OF BENZOYLPHENOXYALKAN CARBON ACIDS WITH ANTI-LIPEMIC AND ANTICHOLESTEROLEMIC ACTION, AND PHARMACEUTICAL PREPARATIONS CONTAINING SUCH COMPOUND.
GR59030A GR72241B (en) 1978-05-09 1979-05-07
FR7911587A FR2425425A1 (en) 1978-05-09 1979-05-08 BENZOYLPHENOXYALCANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES
AT0343279A AT367016B (en) 1978-05-09 1979-05-08 METHOD FOR PRODUCING NEW BENZOYLPHENOXY ALKANIC ACID DERIVATIVES AND THEIR SALTS WITH ACIDS OR. BASE
BE2/57777A BE876094A (en) 1978-05-09 1979-05-08 BENZOLPHENOXYALCANOIC ACID DERIVATIVES EXERCISING NORMOLIPEMATING ACTIVITY
JP5623479A JPS54163560A (en) 1978-05-09 1979-05-08 Benzoylphenoxyalkanoic acid
NO791532A NO791532L (en) 1978-05-09 1979-05-08 PROCEDURE FOR THE PREPARATION OF BENZOYLPHENOXYAL CANCER
ES480329A ES480329A1 (en) 1978-05-09 1979-05-08 Derivatives of benzoylphenoxyalkanoic acids having normolipemizing activity
DK189479A DK189479A (en) 1978-05-09 1979-05-08 PROCEDURE FOR THE PREPARATION OF BENZOYLPHENOXYALKANIC ACID DERIVATIVES
YU01077/79A YU107779A (en) 1978-05-09 1979-05-08 Process for preparing derivatives of benzoylphenoxyalkanoic acid, which normalize the blood lipide level
SE7903982A SE7903982L (en) 1978-05-09 1979-05-08 DERIVATIVES OF BENZOYLPHENOXIAL OFFICES
DE19792918748 DE2918748A1 (en) 1978-05-09 1979-05-09 BENZOYLPHENOXYALCANIC ACID DERIVATIVES, THE PROCESS FOR THEIR MANUFACTURING AND MEDICINAL PRODUCTS CONTAINING SUCH
GB7916093A GB2025394B (en) 1978-05-09 1979-05-09 Benzoylphenoxyalkanoic acid derivatives their use and preparation
US06/123,454 US4296125A (en) 1978-05-09 1980-02-21 Derivatives of benzoylphenoxyalkanoic acids having normolipemizing activity
US06/255,430 US4378373A (en) 1978-05-09 1981-04-20 Derivatives of benzoylphenoxyalkanoic acids having normolipemizing activity
US06/255,431 US4515809A (en) 1978-05-09 1981-04-20 Derivatives of benzoylphenoxyalkanoic acids having normolipemizing activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03426/78A IT1106666B (en) 1978-05-09 1978-05-09 DERIVATIVES OF BENZOYLPHENOXYL ALCHYL ACIDS WITH NORMOLIPEMIZING ACTION

Publications (2)

Publication Number Publication Date
IT7803426A0 IT7803426A0 (en) 1978-05-09
IT1106666B true IT1106666B (en) 1985-11-18

Family

ID=11107132

Family Applications (1)

Application Number Title Priority Date Filing Date
IT03426/78A IT1106666B (en) 1978-05-09 1978-05-09 DERIVATIVES OF BENZOYLPHENOXYL ALCHYL ACIDS WITH NORMOLIPEMIZING ACTION

Country Status (3)

Country Link
JP (1) JPS54163560A (en)
BE (1) BE876094A (en)
IT (1) IT1106666B (en)

Also Published As

Publication number Publication date
BE876094A (en) 1979-09-03
JPS54163560A (en) 1979-12-26
IT7803426A0 (en) 1978-05-09

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