IT1094967B - Topical antiandrogenic compsn. for acne and seborrhoea - contains isobutyric acid 3-tri:fluoromethyl-4-nitro-anilide - Google Patents

Topical antiandrogenic compsn. for acne and seborrhoea - contains isobutyric acid 3-tri:fluoromethyl-4-nitro-anilide

Info

Publication number
IT1094967B
IT1094967B IT2280278A IT2280278A IT1094967B IT 1094967 B IT1094967 B IT 1094967B IT 2280278 A IT2280278 A IT 2280278A IT 2280278 A IT2280278 A IT 2280278A IT 1094967 B IT1094967 B IT 1094967B
Authority
IT
Italy
Prior art keywords
anilide
compsn
isobutyric acid
seborrhoea
fluoromethyl
Prior art date
Application number
IT2280278A
Other languages
Italian (it)
Other versions
IT7822802A0 (en
Inventor
Jose Sebastian Franzone
Teresio Tamietto
Original Assignee
Abc Ist Biolog Chem Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abc Ist Biolog Chem Spa filed Critical Abc Ist Biolog Chem Spa
Priority to IT2280278A priority Critical patent/IT1094967B/en
Publication of IT7822802A0 publication Critical patent/IT7822802A0/en
Priority to BE2057236A priority patent/BE870019A/en
Application granted granted Critical
Publication of IT1094967B publication Critical patent/IT1094967B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compsn. contains active constituent isobutyric acid 3-trifluoromethyl-4-nitroanilide. Used for topical treatment by virtue of the antiandrogenic activity. Composn. is well tolerated by local application. A typical lotion for application 2 or 3 times daily contained the anilide (2.5g) and essence of lemon and bergamot (0.1kg) in propylene glycol to a total of 100g.
IT2280278A 1978-04-28 1978-04-28 Topical antiandrogenic compsn. for acne and seborrhoea - contains isobutyric acid 3-tri:fluoromethyl-4-nitro-anilide IT1094967B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT2280278A IT1094967B (en) 1978-04-28 1978-04-28 Topical antiandrogenic compsn. for acne and seborrhoea - contains isobutyric acid 3-tri:fluoromethyl-4-nitro-anilide
BE2057236A BE870019A (en) 1978-04-28 1978-08-29 PHARMACEUTICAL PREPARATION WITH ANTI-ANDROGENIC ACTIVITY

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2280278A IT1094967B (en) 1978-04-28 1978-04-28 Topical antiandrogenic compsn. for acne and seborrhoea - contains isobutyric acid 3-tri:fluoromethyl-4-nitro-anilide

Publications (2)

Publication Number Publication Date
IT7822802A0 IT7822802A0 (en) 1978-04-28
IT1094967B true IT1094967B (en) 1985-08-10

Family

ID=11200588

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2280278A IT1094967B (en) 1978-04-28 1978-04-28 Topical antiandrogenic compsn. for acne and seborrhoea - contains isobutyric acid 3-tri:fluoromethyl-4-nitro-anilide

Country Status (2)

Country Link
BE (1) BE870019A (en)
IT (1) IT1094967B (en)

Also Published As

Publication number Publication date
IT7822802A0 (en) 1978-04-28
BE870019A (en) 1978-12-18

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