IT1052106B - Nicotinamide derivs - having an analgesic, anti-inflammatory, anti-pyretic and anti-histaminic action - Google Patents

Nicotinamide derivs - having an analgesic, anti-inflammatory, anti-pyretic and anti-histaminic action

Info

Publication number
IT1052106B
IT1052106B IT1085766A IT1085766A IT1052106B IT 1052106 B IT1052106 B IT 1052106B IT 1085766 A IT1085766 A IT 1085766A IT 1085766 A IT1085766 A IT 1085766A IT 1052106 B IT1052106 B IT 1052106B
Authority
IT
Italy
Prior art keywords
inflammatory
pyretic
nicotinamide
analgesic
action
Prior art date
Application number
IT1085766A
Other languages
Italian (it)
Original Assignee
Stabilimenti Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stabilimenti Farma Spa filed Critical Stabilimenti Farma Spa
Priority to IT1085766A priority Critical patent/IT1052106B/en
Priority to GB25836/66A priority patent/GB1146183A/en
Priority to US556562A priority patent/US3420839A/en
Priority to CH867266A priority patent/CH478131A/en
Priority to BE682870D priority patent/BE682870A/xx
Priority to NL666608801A priority patent/NL148318B/en
Priority to BR180794/66A priority patent/BR6680794D0/en
Priority to FR67683A priority patent/FR1485249A/en
Priority to DE19661620490 priority patent/DE1620490A1/en
Priority to FR67682A priority patent/FR5632M/fr
Application granted granted Critical
Publication of IT1052106B publication Critical patent/IT1052106B/en

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  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compounds (I) where R = normal-chain or side-chain alkyl group (C1-6) or arylalkyl group which may or may not be substituted with halogen, OH or OCH3. The compounds have antipyretic and anti-inflammatory action, as well as anti-histaminic, anti-convulsive, hypnogenic and sedative action, and action against biological liquids produced in vivo by phlogistic agents. Compound (Ia) has an anti-pyretic, analgesic, and anti-inflammatory activity greater than that of amino-pyrine, while its toxicity is less than that of amino-pyrine. Unlike aminopyrine, phenylbutazone and nicotinamide, compound (Ia) has anti-histaminic effects.
IT1085766A 1965-07-01 1966-05-12 Nicotinamide derivs - having an analgesic, anti-inflammatory, anti-pyretic and anti-histaminic action IT1052106B (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT1085766A IT1052106B (en) 1966-05-12 1966-05-12 Nicotinamide derivs - having an analgesic, anti-inflammatory, anti-pyretic and anti-histaminic action
GB25836/66A GB1146183A (en) 1965-07-01 1966-06-09 Improvements in or relating to nicotinamide derivatives having an analgesic, anti-inflammatory, antipyretic and anti-histaminic action, method for their preparation, andtherapeutical use
CH867266A CH478131A (en) 1965-07-01 1966-06-10 Process for the production of a nicotinic acid amide derivative with an anti-pain, antipyretic, anti-inflammatory and antihistaminic effect
US556562A US3420839A (en) 1965-07-01 1966-06-10 Aminomethyl pyrazolone derivatives of nicotinamide
BE682870D BE682870A (en) 1965-07-01 1966-06-21
NL666608801A NL148318B (en) 1965-07-01 1966-06-24 PROCESS FOR PREPARING A THERAPEUTIC PREPARATION WITH ANTIPYRETIC AND ANTI-INFLAMMATORY ACTION, FORMED PREPARATION, AND PROCESS FOR PREPARING AN ACTIVE NICOTINIC ACID AMIDE DERIVATIVE.
BR180794/66A BR6680794D0 (en) 1965-07-01 1966-06-28 PROCESS OF OBTAINING NICOTINAMIDE DERIVATIVES WITH ANTI-INFLAMMATORY ANTI-INFLAMMATORY ACTION
FR67683A FR1485249A (en) 1965-07-01 1966-06-30 Process for preparing nicotinamide derivatives
DE19661620490 DE1620490A1 (en) 1965-07-01 1966-06-30 Process for the production of new nicotinamide derivatives with analgesic, antipyretic, anti-inflammatory and antihistaminic effects
FR67682A FR5632M (en) 1965-07-01 1966-06-30

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1085766A IT1052106B (en) 1966-05-12 1966-05-12 Nicotinamide derivs - having an analgesic, anti-inflammatory, anti-pyretic and anti-histaminic action

Publications (1)

Publication Number Publication Date
IT1052106B true IT1052106B (en) 1981-06-20

Family

ID=11134454

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1085766A IT1052106B (en) 1965-07-01 1966-05-12 Nicotinamide derivs - having an analgesic, anti-inflammatory, anti-pyretic and anti-histaminic action

Country Status (1)

Country Link
IT (1) IT1052106B (en)

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