IS6766A - Pravastatin sodium, largely free of pravastatin lactone and epi-pravastatin, and mixtures containing it - Google Patents
Pravastatin sodium, largely free of pravastatin lactone and epi-pravastatin, and mixtures containing itInfo
- Publication number
- IS6766A IS6766A IS6766A IS6766A IS6766A IS 6766 A IS6766 A IS 6766A IS 6766 A IS6766 A IS 6766A IS 6766 A IS6766 A IS 6766A IS 6766 A IS6766 A IS 6766A
- Authority
- IS
- Iceland
- Prior art keywords
- pravastatin
- epi
- lactone
- mixtures containing
- largely free
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic System
- C07F1/04—Sodium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23827800P | 2000-10-05 | 2000-10-05 | |
PCT/US2001/031230 WO2002030415A1 (en) | 2000-10-05 | 2001-10-05 | Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same |
Publications (1)
Publication Number | Publication Date |
---|---|
IS6766A true IS6766A (en) | 2003-04-01 |
Family
ID=22897222
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IS6766A IS6766A (en) | 2000-10-05 | 2003-04-01 | Pravastatin sodium, largely free of pravastatin lactone and epi-pravastatin, and mixtures containing it |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1330245A4 (en) |
JP (6) | JP3737801B2 (en) |
KR (1) | KR20030059173A (en) |
CN (1) | CN1468098A (en) |
AU (1) | AU2002211462A1 (en) |
CA (1) | CA2422744A1 (en) |
CZ (1) | CZ20031166A3 (en) |
HR (1) | HRP20030347A2 (en) |
HU (1) | HUP0400913A2 (en) |
IL (1) | IL155194A0 (en) |
IS (1) | IS6766A (en) |
MX (1) | MXPA03002963A (en) |
NO (1) | NO20031532D0 (en) |
NZ (1) | NZ525631A (en) |
PL (1) | PL361230A1 (en) |
SK (1) | SK5232003A3 (en) |
WO (1) | WO2002030415A1 (en) |
ZA (1) | ZA200302313B (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1798214A3 (en) * | 1999-11-30 | 2007-08-01 | Teva Gyogyszergyár Zártköruen Muködo Részvenytarsaság | Process for recovering statin compounds from a fermentation broth |
EP1481674B1 (en) * | 1999-11-30 | 2008-01-02 | TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság | Process for recovering statin compounds from a fermentation broth |
MXPA02005283A (en) * | 1999-11-30 | 2003-10-06 | Biogal Gyogyszergyar | Process for recovering statin compounds from a fermentation broth. |
PL364929A1 (en) | 1999-12-14 | 2004-12-27 | Biogal Gyogyszergyar Rt. | Novel forms of pravastatin sodium |
CZ20031166A3 (en) * | 2000-10-05 | 2004-04-14 | Biogal Gyogyszergyar Rt | Pravastatin sodium salt that is substantially free of pravastatin lactone and epi-pravastatin as well as composition based thereon |
JP3236282B1 (en) * | 2000-10-16 | 2001-12-10 | 三共株式会社 | How to purify pravastatin |
GB0218781D0 (en) | 2002-08-13 | 2002-09-18 | Astrazeneca Ab | Chemical process |
EP1452519A1 (en) * | 2003-02-25 | 2004-09-01 | Balkanpharma-Razgrad AD | Method for the isolation and purification of pravastatin sodium |
GB0312896D0 (en) | 2003-06-05 | 2003-07-09 | Astrazeneca Ab | Chemical process |
UY28501A1 (en) | 2003-09-10 | 2005-04-29 | Astrazeneca Uk Ltd | CHEMICAL COMPOUNDS |
GB0324791D0 (en) | 2003-10-24 | 2003-11-26 | Astrazeneca Ab | Chemical process |
US7425644B2 (en) * | 2003-11-24 | 2008-09-16 | TEVA Gyógyszergyár Zártkörűen Működő Részvénytársaság | Method of purifying pravastatin |
NZ552389A (en) | 2004-08-06 | 2009-05-31 | Transform Pharmaceuticals Inc | Statin pharmaceutical compositions and related methods of treatment |
ES2254028B1 (en) * | 2004-11-29 | 2007-03-01 | Ercros Industrial, S.A. | PROCEDURE FOR OBTAINING PRAVASTATIN SODIUM PURIFIED. |
EP1851223A1 (en) * | 2005-02-25 | 2007-11-07 | Teva Pharmaceutical Industries Ltd | Process of purifying tadalafil |
JP4813841B2 (en) * | 2005-07-25 | 2011-11-09 | キユーピー株式会社 | Method for producing pravastatin sodium |
HU229260B1 (en) * | 2010-11-29 | 2013-10-28 | Egis Gyogyszergyar Nyrt | Process for preparation of rosuvastatin salts |
CN114031496A (en) * | 2021-11-30 | 2022-02-11 | 广东蓝宝制药有限公司 | Preparation method of high-purity pravastatin 1,1,3, 3-tetramethylbutylamine |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3378441A (en) * | 1963-10-17 | 1968-04-16 | S B Penick & Company | Tetraene antibiotic purification |
JPS5221594B2 (en) * | 1973-09-29 | 1977-06-11 | ||
JPS51101994A (en) * | 1975-02-07 | 1976-09-08 | Glaxo Lab Ltd | |
US4231938A (en) * | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
MX7065E (en) * | 1980-06-06 | 1987-04-10 | Sankyo Co | A MICROBIOLOGICAL PROCEDURE FOR PREPARING DERIVATIVES OF ML-236B |
JPS572240A (en) * | 1980-06-06 | 1982-01-07 | Sankyo Co Ltd | Ml-236b derivative |
JPS5889191A (en) * | 1981-11-20 | 1983-05-27 | Sankyo Co Ltd | Preparation of 3-hydroxy-ml-236b derivative |
JPS5890509A (en) * | 1981-11-25 | 1983-05-30 | Sankyo Co Ltd | Composition for remedy of hypercholesterolemia |
JPH01190661A (en) * | 1988-01-22 | 1989-07-31 | Konishi Kagaku Kogyo Kk | Purification of 4,4'-dihydroxydiphenylsulfone |
JP2739328B2 (en) * | 1988-09-14 | 1998-04-15 | 日本ケミファ株式会社 | Purification method of benzimidazole compound |
US5202029A (en) * | 1991-03-13 | 1993-04-13 | Caron Kabushiki Kaisha | Process for purification of hmg-coa reductase inhibitors |
NZ250609A (en) * | 1992-12-28 | 1995-07-26 | Sankyo Co | Hexahydronaphthalene esters and ring closed lactones; preparation and medicaments |
JPH06256278A (en) * | 1993-03-03 | 1994-09-13 | Nissan Chem Ind Ltd | Optically active alpha-carbamoylalkanoic acid derivative and its production |
CA2126365C (en) * | 1993-07-06 | 1999-08-24 | Steven W. Felman | Recovery of citric acid from impure process streams by addition of strong acids and salts thereof |
MX9604372A (en) * | 1994-03-31 | 1997-06-28 | Pfizer | Process for natamycin recovery. |
ES2145479T3 (en) * | 1995-08-03 | 2000-07-01 | Dsm Nv | IMPROVED PROCEDURE FOR OBTAINING LOVASTATIN, COMPACTINE OR PRAVASTATIN. |
JPH09124655A (en) * | 1995-11-01 | 1997-05-13 | Sankyo Co Ltd | New squalene synthase inhibition-active compound |
EP0877089A1 (en) * | 1997-05-07 | 1998-11-11 | Gist-Brocades B.V. | HMG-CoA reductase inhibitor preparation process |
SI20070A (en) * | 1998-09-18 | 2000-04-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | NOVEL SALTS OF INHIBITORS OF HMG-CoA REDUCTASE |
SI20072A (en) * | 1998-09-18 | 2000-04-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | PROCEDURE OF PREPARATION OF INHIBITORS OF HMG-CoA REDUCTASE |
JP2000229855A (en) * | 1998-12-07 | 2000-08-22 | Satoshi Takebe | Pravastatin sodium tablet |
ATE294771T1 (en) * | 1999-02-03 | 2005-05-15 | Inst Drug Res Ltd | MICROBIAL PROCESS FOR PRODUCING PRAVASTATIN |
HUP9902352A1 (en) * | 1999-07-12 | 2000-09-28 | Gyógyszerkutató Intézet Kft. | Process for producing pravastatin by microbiological way |
MXPA02005283A (en) * | 1999-11-30 | 2003-10-06 | Biogal Gyogyszergyar | Process for recovering statin compounds from a fermentation broth. |
CZ20031166A3 (en) * | 2000-10-05 | 2004-04-14 | Biogal Gyogyszergyar Rt | Pravastatin sodium salt that is substantially free of pravastatin lactone and epi-pravastatin as well as composition based thereon |
-
2001
- 2001-10-05 CZ CZ20031166A patent/CZ20031166A3/en unknown
- 2001-10-05 CA CA002422744A patent/CA2422744A1/en not_active Abandoned
- 2001-10-05 EP EP01979511A patent/EP1330245A4/en not_active Withdrawn
- 2001-10-05 CN CNA018168604A patent/CN1468098A/en active Pending
- 2001-10-05 SK SK523-2003A patent/SK5232003A3/en unknown
- 2001-10-05 PL PL01361230A patent/PL361230A1/en unknown
- 2001-10-05 AU AU2002211462A patent/AU2002211462A1/en not_active Abandoned
- 2001-10-05 NZ NZ525631A patent/NZ525631A/en unknown
- 2001-10-05 KR KR10-2003-7004764A patent/KR20030059173A/en not_active IP Right Cessation
- 2001-10-05 WO PCT/US2001/031230 patent/WO2002030415A1/en not_active Application Discontinuation
- 2001-10-05 MX MXPA03002963A patent/MXPA03002963A/en not_active Application Discontinuation
- 2001-10-05 IL IL15519401A patent/IL155194A0/en unknown
- 2001-10-05 JP JP2002533858A patent/JP3737801B2/en not_active Expired - Fee Related
- 2001-10-05 HU HU0400913A patent/HUP0400913A2/en not_active IP Right Cessation
-
2003
- 2003-03-25 ZA ZA200302313A patent/ZA200302313B/en unknown
- 2003-04-01 IS IS6766A patent/IS6766A/en unknown
- 2003-04-04 NO NO20031532A patent/NO20031532D0/en not_active Application Discontinuation
- 2003-05-02 HR HR20030347A patent/HRP20030347A2/en not_active Application Discontinuation
-
2004
- 2004-09-24 JP JP2004278522A patent/JP2005013238A/en not_active Withdrawn
-
2005
- 2005-08-18 JP JP2005237299A patent/JP2006036781A/en active Pending
-
2009
- 2009-08-21 JP JP2009191951A patent/JP2009268479A/en not_active Withdrawn
-
2013
- 2013-01-25 JP JP2013011711A patent/JP2013128486A/en not_active Withdrawn
-
2015
- 2015-07-31 JP JP2015152088A patent/JP2015212300A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
ZA200302313B (en) | 2004-03-25 |
CN1468098A (en) | 2004-01-14 |
NZ525631A (en) | 2005-05-27 |
JP3737801B2 (en) | 2006-01-25 |
WO2002030415A9 (en) | 2002-10-31 |
PL361230A1 (en) | 2004-10-04 |
HUP0400913A2 (en) | 2006-11-28 |
MXPA03002963A (en) | 2005-01-25 |
JP2015212300A (en) | 2015-11-26 |
AU2002211462A1 (en) | 2002-04-22 |
KR20030059173A (en) | 2003-07-07 |
JP2013128486A (en) | 2013-07-04 |
NO20031532L (en) | 2003-04-04 |
SK5232003A3 (en) | 2004-06-08 |
CZ20031166A3 (en) | 2004-04-14 |
JP2004510817A (en) | 2004-04-08 |
CA2422744A1 (en) | 2002-04-18 |
HRP20030347A2 (en) | 2005-04-30 |
EP1330245A1 (en) | 2003-07-30 |
JP2005013238A (en) | 2005-01-20 |
IL155194A0 (en) | 2003-11-23 |
JP2009268479A (en) | 2009-11-19 |
NO20031532D0 (en) | 2003-04-04 |
WO2002030415A1 (en) | 2002-04-18 |
JP2006036781A (en) | 2006-02-09 |
EP1330245A4 (en) | 2004-10-20 |
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