IS6715A - Imidazol-5-yl-2-anilino-pyrimidine, which mediates cell proliferation - Google Patents
Imidazol-5-yl-2-anilino-pyrimidine, which mediates cell proliferationInfo
- Publication number
- IS6715A IS6715A IS6715A IS6715A IS6715A IS 6715 A IS6715 A IS 6715A IS 6715 A IS6715 A IS 6715A IS 6715 A IS6715 A IS 6715A IS 6715 A IS6715 A IS 6715A
- Authority
- IS
- Iceland
- Prior art keywords
- anilino
- imidazol
- pyrimidine
- cell proliferation
- mediates cell
- Prior art date
Links
- HMOUISRYHLEUNP-UHFFFAOYSA-N 4-(1h-imidazol-5-yl)-n-phenylpyrimidin-2-amine Chemical compound N=1C=CC(C=2NC=NC=2)=NC=1NC1=CC=CC=C1 HMOUISRYHLEUNP-UHFFFAOYSA-N 0.000 title 1
- 230000004663 cell proliferation Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Adhesives Or Adhesive Processes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0021726.5A GB0021726D0 (en) | 2000-09-05 | 2000-09-05 | Chemical compounds |
| PCT/GB2001/003864 WO2002020512A1 (en) | 2000-09-05 | 2001-08-30 | Imidazolo-5-yl-2-anilino-pyrimidines as agents for the inhibition of the cell proliferation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IS6715A true IS6715A (en) | 2003-02-12 |
| IS2055B IS2055B (en) | 2005-10-14 |
Family
ID=9898838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS6715A IS2055B (en) | 2000-09-05 | 2003-02-12 | Imidazol-5-yl-2-anilino-pyrimidine, which mediates cell proliferation |
Country Status (32)
| Country | Link |
|---|---|
| US (2) | US6969714B2 (en) |
| EP (1) | EP1351958B1 (en) |
| JP (1) | JP3523641B2 (en) |
| KR (1) | KR100802368B1 (en) |
| CN (1) | CN1269813C (en) |
| AR (1) | AR033836A1 (en) |
| AT (1) | ATE269327T1 (en) |
| AU (2) | AU2001284192B2 (en) |
| BG (1) | BG107579A (en) |
| BR (1) | BR0113496A (en) |
| CA (1) | CA2417148C (en) |
| CZ (1) | CZ2003617A3 (en) |
| DE (1) | DE60103935T2 (en) |
| DK (1) | DK1351958T3 (en) |
| EE (1) | EE05430B1 (en) |
| ES (1) | ES2221904T3 (en) |
| GB (1) | GB0021726D0 (en) |
| HU (1) | HUP0302922A3 (en) |
| IL (1) | IL154292A0 (en) |
| IS (1) | IS2055B (en) |
| MX (1) | MXPA03001511A (en) |
| MY (1) | MY127126A (en) |
| NO (1) | NO324059B1 (en) |
| NZ (1) | NZ523787A (en) |
| PL (1) | PL360627A1 (en) |
| PT (1) | PT1351958E (en) |
| RU (1) | RU2284327C2 (en) |
| SK (1) | SK287277B6 (en) |
| TW (1) | TWI242559B (en) |
| UA (1) | UA74206C2 (en) |
| WO (1) | WO2002020512A1 (en) |
| ZA (1) | ZA200300612B (en) |
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| GB9828511D0 (en) | 1998-12-24 | 1999-02-17 | Zeneca Ltd | Chemical compounds |
| GB9919778D0 (en) | 1999-08-21 | 1999-10-27 | Zeneca Ltd | Chemical compounds |
| GB0004887D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0004888D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0004886D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0004890D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0007371D0 (en) | 2000-03-28 | 2000-05-17 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0016877D0 (en) | 2000-07-11 | 2000-08-30 | Astrazeneca Ab | Chemical compounds |
| US7122544B2 (en) * | 2000-12-06 | 2006-10-17 | Signal Pharmaceuticals, Llc | Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto |
| US7129242B2 (en) | 2000-12-06 | 2006-10-31 | Signal Pharmaceuticals, Llc | Anilinopyrimidine derivatives as JNK pathway inhibitors and compositions and methods related thereto |
| GB0103926D0 (en) | 2001-02-17 | 2001-04-04 | Astrazeneca Ab | Chemical compounds |
| GB0113041D0 (en) | 2001-05-30 | 2001-07-18 | Astrazeneca Ab | Chemical compounds |
| JP2005524672A (en) * | 2002-03-09 | 2005-08-18 | アストラゼネカ アクチボラグ | Imidazolyl-substituted pyrimidine derivatives having CDK inhibitory activity |
| GB0205693D0 (en) * | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
| GB0205690D0 (en) * | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
| GB0205688D0 (en) * | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
| AR039241A1 (en) * | 2002-04-04 | 2005-02-16 | Biogen Inc | HETEROARILOS TRISUSTITUIDOS AND METHODS FOR ITS PRODUCTION AND USE OF THE SAME |
| DE10239042A1 (en) * | 2002-08-21 | 2004-03-04 | Schering Ag | New fused macrocyclic pyrimidine derivatives, useful as e.g. cyclin-dependent kinase inhibitors for treating e.g. cancer, autoimmune, cardiovascular or neurodegenerative diseases or viral infections |
| UA80295C2 (en) * | 2002-09-06 | 2007-09-10 | Biogen Inc | Pyrazolopyridines and using the same |
| GB0226583D0 (en) * | 2002-11-14 | 2002-12-18 | Cyclacel Ltd | Compounds |
| GB0311274D0 (en) * | 2003-05-16 | 2003-06-18 | Astrazeneca Ab | Chemical compounds |
| GB0311276D0 (en) * | 2003-05-16 | 2003-06-18 | Astrazeneca Ab | Chemical compounds |
| GB0402277D0 (en) * | 2004-02-03 | 2004-03-10 | Astrazeneca Ab | Chemical compounds |
| TW200528101A (en) * | 2004-02-03 | 2005-09-01 | Astrazeneca Ab | Chemical compounds |
| KR20070084067A (en) * | 2004-10-13 | 2007-08-24 | 와이어쓰 | N-benzenesulfonyl substituted anilino-pyrimidine analogs |
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| CN1939910A (en) * | 2004-12-31 | 2007-04-04 | 孙飘扬 | Amino-metadiazine compound and its salt, its preparation and pharmaceutical use |
| GB0504753D0 (en) * | 2005-03-08 | 2005-04-13 | Astrazeneca Ab | Chemical compounds |
| CA2617170A1 (en) | 2005-07-30 | 2007-02-08 | Astrazeneca Ab | Imidazolyl-pyrimidine compounds for use in the treatment of proliferative disorders |
| KR100674813B1 (en) * | 2005-08-05 | 2007-01-29 | 일양약품주식회사 | N-phenyl-2-pyrimidine-amine derivatives and preparation method thereof |
| BRPI0616722A2 (en) | 2005-09-30 | 2012-12-25 | Astrazeneca Ab | compound or a pharmaceutically acceptable salt or an in vivo hydrolysable ester thereof, process for preparing it, pharmaceutical composition, use of a compound or a pharmaceutically acceptable salt or an in vivo hydrolysable ester thereof, and methods for producing an anti-oxidizing effect. -proliferation and an inhibitory effect cdk2, to treat cancer, and to treat diseases |
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| US20090111860A1 (en) * | 2006-04-21 | 2009-04-30 | Astrazeneca Ab | Sulfonamide compounds useful as adg receptor modulators |
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| TW200815418A (en) * | 2006-06-27 | 2008-04-01 | Astrazeneca Ab | New compounds I |
| TW200815417A (en) * | 2006-06-27 | 2008-04-01 | Astrazeneca Ab | New compounds II |
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| DE69933680T2 (en) | 1998-08-29 | 2007-08-23 | Astrazeneca Ab | PYRIMIDINE COMPOUNDS |
| DE69932828T2 (en) | 1998-08-29 | 2007-10-18 | Astrazeneca Ab | PYRIMIDINE COMPOUNDS |
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| AU6476599A (en) * | 1998-11-03 | 2000-05-22 | Novartis Ag | Anti-inflammatory 4-phenyl-5-pyrimidinyl-imidazoles |
| GB9828511D0 (en) | 1998-12-24 | 1999-02-17 | Zeneca Ltd | Chemical compounds |
| GB9903762D0 (en) | 1999-02-18 | 1999-04-14 | Novartis Ag | Organic compounds |
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| GB9919778D0 (en) | 1999-08-21 | 1999-10-27 | Zeneca Ltd | Chemical compounds |
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| GB0004890D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
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-
2000
- 2000-09-05 GB GBGB0021726.5A patent/GB0021726D0/en not_active Ceased
-
2001
- 2001-08-30 CN CNB018151744A patent/CN1269813C/en not_active Expired - Fee Related
- 2001-08-30 NZ NZ523787A patent/NZ523787A/en unknown
- 2001-08-30 EP EP01963159A patent/EP1351958B1/en not_active Expired - Lifetime
- 2001-08-30 CA CA2417148A patent/CA2417148C/en not_active Expired - Fee Related
- 2001-08-30 BR BR0113496-5A patent/BR0113496A/en not_active Application Discontinuation
- 2001-08-30 WO PCT/GB2001/003864 patent/WO2002020512A1/en not_active Ceased
- 2001-08-30 UA UA2003042977A patent/UA74206C2/en unknown
- 2001-08-30 AT AT01963159T patent/ATE269327T1/en active
- 2001-08-30 HU HU0302922A patent/HUP0302922A3/en unknown
- 2001-08-30 CZ CZ2003617A patent/CZ2003617A3/en unknown
- 2001-08-30 US US10/363,655 patent/US6969714B2/en not_active Expired - Fee Related
- 2001-08-30 ES ES01963159T patent/ES2221904T3/en not_active Expired - Lifetime
- 2001-08-30 DE DE60103935T patent/DE60103935T2/en not_active Expired - Lifetime
- 2001-08-30 PL PL36062701A patent/PL360627A1/en not_active Application Discontinuation
- 2001-08-30 DK DK01963159T patent/DK1351958T3/en active
- 2001-08-30 SK SK241-2003A patent/SK287277B6/en not_active IP Right Cessation
- 2001-08-30 RU RU2003109612/04A patent/RU2284327C2/en not_active IP Right Cessation
- 2001-08-30 KR KR1020037003215A patent/KR100802368B1/en not_active Expired - Fee Related
- 2001-08-30 AU AU2001284192A patent/AU2001284192B2/en not_active Ceased
- 2001-08-30 IL IL15429201A patent/IL154292A0/en not_active IP Right Cessation
- 2001-08-30 JP JP2002525133A patent/JP3523641B2/en not_active Expired - Fee Related
- 2001-08-30 MX MXPA03001511A patent/MXPA03001511A/en active IP Right Grant
- 2001-08-30 EE EEP200300088A patent/EE05430B1/en not_active IP Right Cessation
- 2001-08-30 AU AU8419201A patent/AU8419201A/en active Pending
- 2001-08-30 PT PT01963159T patent/PT1351958E/en unknown
- 2001-09-03 MY MYPI20014136 patent/MY127126A/en unknown
- 2001-09-05 AR ARP010104228A patent/AR033836A1/en unknown
- 2001-09-11 TW TW090122494A patent/TWI242559B/en not_active IP Right Cessation
-
2003
- 2003-01-22 ZA ZA200300612A patent/ZA200300612B/en unknown
- 2003-02-12 IS IS6715A patent/IS2055B/en unknown
- 2003-02-21 BG BG107579A patent/BG107579A/en unknown
- 2003-03-04 NO NO20031006A patent/NO324059B1/en not_active IP Right Cessation
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2005
- 2005-06-29 US US11/169,197 patent/US20060004033A1/en not_active Abandoned
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