IN2015DN03114A - - Google Patents
Info
- Publication number
- IN2015DN03114A IN2015DN03114A IN3114DEN2015A IN2015DN03114A IN 2015DN03114 A IN2015DN03114 A IN 2015DN03114A IN 3114DEN2015 A IN3114DEN2015 A IN 3114DEN2015A IN 2015DN03114 A IN2015DN03114 A IN 2015DN03114A
- Authority
- IN
- India
- Prior art keywords
- biphenylyl
- fluoro
- propionic acid
- purification
- synthesis
- Prior art date
Links
- SYTBZMRGLBWNTM-JTQLQIEISA-N (S)-flurbiprofen Chemical compound FC1=CC([C@@H](C(O)=O)C)=CC=C1C1=CC=CC=C1 SYTBZMRGLBWNTM-JTQLQIEISA-N 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/02—Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1216893.6A GB201216893D0 (en) | 2012-09-21 | 2012-09-21 | Drug substance preparations, pharmaceutical compositions and dosage forms comprising s-(+)-flurbiprofen |
| PCT/GB2013/052464 WO2014045046A2 (en) | 2012-09-21 | 2013-09-20 | Drug substance preparations, pharmaceutical compositions and dosage forms comprising s-(+)-flurbiprofen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2015DN03114A true IN2015DN03114A (OSRAM) | 2015-10-02 |
Family
ID=47190400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3114DEN2015 IN2015DN03114A (OSRAM) | 2012-09-21 | 2013-09-20 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20150232407A1 (OSRAM) |
| EP (1) | EP2897602A2 (OSRAM) |
| JP (2) | JP2014062080A (OSRAM) |
| AU (2) | AU2013320004A1 (OSRAM) |
| CA (1) | CA2884173C (OSRAM) |
| GB (1) | GB201216893D0 (OSRAM) |
| IN (1) | IN2015DN03114A (OSRAM) |
| WO (1) | WO2014045046A2 (OSRAM) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2962034A1 (en) * | 2014-10-07 | 2016-04-14 | Taisho Pharmaceutical Co., Ltd. | External preparation composition containing s-flurbiprofen |
| CN113651689B (zh) * | 2021-08-27 | 2022-06-10 | 上海博悦生物科技有限公司 | S-氟比洛芬钠新晶型及其制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4209638A (en) | 1977-03-08 | 1980-06-24 | The Boots Company Limited | Preparation of therapeutic agents |
| DE3824353A1 (de) | 1988-07-19 | 1990-01-25 | Paz Arzneimittelentwicklung | Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren |
| US5190981A (en) * | 1989-08-17 | 1993-03-02 | Sepracor Inc. | Formulation containing S(+) enantiomer of flurbiprofen or ketoprofen and method of use for oral administration for prevention and treatment of bone loss associated with periodontal disease |
| US5015764A (en) | 1990-06-18 | 1991-05-14 | Ethyl Corporation | Preparation of optically active aliphatic carboxylic acids |
| DK0508307T3 (da) | 1991-04-08 | 1995-12-27 | Sumitomo Chemical Co | Optisk aktive sekundære aminforbindelser, fremgangsmåde til fremstilling af en optisk aktiv sekundær aminforbindelse og fremgangsmåde til fremstilling af en optisk aktiv carboxylsyre ved anvendelse af denne forbindelse |
| US5235100A (en) | 1992-01-24 | 1993-08-10 | Ethyl Corporation | Preparation of optically active aliphatic carboxylic acids |
| ES2100037T3 (es) * | 1992-12-02 | 1997-06-01 | Knoll Ag | Proceso para preparar enantiomeros sustancialmente puros de acidos fenilpropionicos. |
| JP3782834B2 (ja) * | 1994-10-26 | 2006-06-07 | 株式会社トクホン | 鎮痛抗炎症貼付剤 |
| US5574183A (en) | 1995-01-24 | 1996-11-12 | Albemarle Corporation | Preparation of optically active aliphatic carboxylic acids |
| GB9523833D0 (en) | 1995-11-22 | 1996-01-24 | Boots Co Plc | Medical treatment |
| JP2006335639A (ja) * | 2003-01-23 | 2006-12-14 | Nagase & Co Ltd | 光学活性なフルルビプロフェンの製造方法 |
| WO2008095186A1 (en) * | 2007-02-01 | 2008-08-07 | Myriad Genetics, Inc. | Drug substance preparations, pharmaceutical compositions and dosage forms |
| GB0811851D0 (en) * | 2008-06-30 | 2008-07-30 | Aesica Pharmaceuticals Ltd | Process |
-
2012
- 2012-09-21 GB GBGB1216893.6A patent/GB201216893D0/en not_active Ceased
- 2012-10-05 JP JP2012222973A patent/JP2014062080A/ja active Pending
-
2013
- 2013-09-20 CA CA2884173A patent/CA2884173C/en active Active
- 2013-09-20 US US14/429,607 patent/US20150232407A1/en not_active Abandoned
- 2013-09-20 WO PCT/GB2013/052464 patent/WO2014045046A2/en not_active Ceased
- 2013-09-20 AU AU2013320004A patent/AU2013320004A1/en not_active Abandoned
- 2013-09-20 IN IN3114DEN2015 patent/IN2015DN03114A/en unknown
- 2013-09-20 EP EP13786529.1A patent/EP2897602A2/en not_active Ceased
-
2017
- 2017-09-11 JP JP2017173960A patent/JP2018035165A/ja active Pending
- 2017-12-21 AU AU2017279760A patent/AU2017279760A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017279760A1 (en) | 2018-02-01 |
| JP2018035165A (ja) | 2018-03-08 |
| WO2014045046A3 (en) | 2014-06-26 |
| US20150232407A1 (en) | 2015-08-20 |
| WO2014045046A2 (en) | 2014-03-27 |
| AU2013320004A1 (en) | 2015-04-30 |
| CA2884173C (en) | 2023-03-14 |
| JP2014062080A (ja) | 2014-04-10 |
| EP2897602A2 (en) | 2015-07-29 |
| CA2884173A1 (en) | 2014-03-27 |
| GB201216893D0 (en) | 2012-11-07 |
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