IN2015DN02699A - - Google Patents

Info

Publication number
IN2015DN02699A
IN2015DN02699A IN2699DEN2015A IN2015DN02699A IN 2015DN02699 A IN2015DN02699 A IN 2015DN02699A IN 2699DEN2015 A IN2699DEN2015 A IN 2699DEN2015A IN 2015DN02699 A IN2015DN02699 A IN 2015DN02699A
Authority
IN
India
Prior art keywords
dosages
eye
compositions
methods
relates
Prior art date
Application number
Inventor
Anton Ana Isabel Jimenez
Fajardo Victoria Gonzalez
Palomar Veronica Ruz
Original Assignee
Sylentis Sau
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sylentis Sau filed Critical Sylentis Sau
Publication of IN2015DN02699A publication Critical patent/IN2015DN02699A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/30—Special therapeutic applications
    • C12N2320/32—Special delivery means, e.g. tissue-specific

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Epidemiology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to methods , compositions and dosages that decrease IOP of the eye , comprising a 19 nucleotide double- stranded RNA molecule.
IN2699DEN2015 2012-09-05 2012-09-05 IN2015DN02699A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB2012/052177 WO2014037686A1 (en) 2012-09-05 2012-09-05 Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions

Publications (1)

Publication Number Publication Date
IN2015DN02699A true IN2015DN02699A (en) 2015-09-04

Family

ID=46889366

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2699DEN2015 IN2015DN02699A (en) 2012-09-05 2012-09-05

Country Status (19)

Country Link
US (1) US10011832B2 (en)
EP (1) EP2893018B1 (en)
JP (1) JP2015533792A (en)
KR (1) KR102120060B1 (en)
CN (1) CN104781402A (en)
AU (1) AU2012389270B2 (en)
BR (1) BR112015004452A2 (en)
CA (1) CA2883007A1 (en)
CL (1) CL2015000538A1 (en)
EC (1) ECSP15011105A (en)
ES (1) ES2750125T3 (en)
HK (1) HK1211983A1 (en)
IL (1) IL237403B (en)
IN (1) IN2015DN02699A (en)
MX (1) MX368084B (en)
RU (1) RU2653766C2 (en)
SG (1) SG11201501385UA (en)
WO (1) WO2014037686A1 (en)
ZA (1) ZA201502181B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2015DN02699A (en) 2012-09-05 2015-09-04 Sylentis Sau
US10011837B2 (en) 2014-03-04 2018-07-03 Sylentis Sau SiRNAs and their use in methods and compositions for the treatment and/or prevention of eye conditions

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Also Published As

Publication number Publication date
SG11201501385UA (en) 2015-03-30
CA2883007A1 (en) 2014-03-13
AU2012389270B2 (en) 2018-11-08
WO2014037686A1 (en) 2014-03-13
CL2015000538A1 (en) 2015-07-31
BR112015004452A2 (en) 2017-08-08
MX2015002800A (en) 2015-07-17
KR20150048880A (en) 2015-05-07
IL237403B (en) 2019-11-28
ECSP15011105A (en) 2015-12-31
ZA201502181B (en) 2016-01-27
HK1211983A1 (en) 2016-06-03
AU2012389270A1 (en) 2015-02-26
EP2893018A1 (en) 2015-07-15
MX368084B (en) 2019-09-19
ES2750125T3 (en) 2020-03-25
CN104781402A (en) 2015-07-15
JP2015533792A (en) 2015-11-26
RU2015112131A (en) 2016-10-27
US10011832B2 (en) 2018-07-03
US20150259677A1 (en) 2015-09-17
KR102120060B1 (en) 2020-06-09
IL237403A0 (en) 2015-04-30
RU2653766C2 (en) 2018-05-14
EP2893018B1 (en) 2019-07-24

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